Study of the Efficacy and Safety of Alirocumab (REGN727/SAR236553) in Combination With Other Lipid-modifying Treatment (LMT) (ODYSSEY OPTIONS I)
Public ClinicalTrials.gov record NCT01730040. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind Study of the Efficacy and Safety of Alirocumab Added on to Atorvastatin Versus Ezetimibe Added on to Atorvastatin Versus Atorvastatin Dose Increase Versus Switch to Rosuvastatin in Patients Who Are Not Controlled on Atorvastatin
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a randomized, double-blind, active-comparator, parallel-group study in patients at high cardiovascular risk with nonfamilial hypercholesterolemia or heterozygous familial hypercholesterolemia (heFH).
Study identification
- NCT ID
- NCT01730040
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 355 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2012 (Type not available)
- Primary completion
- Apr 2014 (Actual)
- Completion
- May 2014 (Actual)
- Last update posted
- Aug 31, 2015
2012 – 2014
United States locations
- U.S. sites
- 56
- U.S. states
- 27
- U.S. cities
- 56
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Mobile | Alabama | — | — |
| Not listed | Chandler | Arizona | — | — |
| Not listed | Tucson | Arizona | — | — |
| Not listed | Anaheim | California | — | — |
| Not listed | Beverly Hills | California | — | — |
| Not listed | Lakeland Village | California | — | — |
| Not listed | Newport Beach | California | — | — |
| Not listed | Northridge | California | — | — |
| Not listed | Sacramento | California | — | — |
| Not listed | Walnut Creek | California | — | — |
| Not listed | Milford | Connecticut | — | — |
| Not listed | Atlantis | Florida | — | — |
| Not listed | Boca Raton | Florida | — | — |
| Not listed | Clearwater | Florida | — | — |
| Not listed | Jacksonville | Florida | — | — |
| Not listed | Miami (2 Locations) | Florida | — | — |
| Not listed | Oviedo | Florida | — | — |
| Not listed | Pinellas Park | Florida | — | — |
| Not listed | Port Orange | Florida | — | — |
| Not listed | Sarasota | Florida | — | — |
| Not listed | Tampa | Florida | — | — |
| Not listed | West Palm Beach | Florida | — | — |
| Not listed | Boise | Idaho | — | — |
| Not listed | Meridian | Idaho | — | — |
| Not listed | Chicago | Illinois | — | — |
| Not listed | Morton | Illinois | — | — |
| Not listed | Indianapolis | Indiana | — | — |
| Not listed | Newton | Kansas | — | — |
| Not listed | Overland Park | Kansas | — | — |
| Not listed | Wichita | Kansas | — | — |
| Not listed | Lexington | Kentucky | — | — |
| Not listed | Louisville | Kentucky | — | — |
| Not listed | Auburn | Maine | — | — |
| Not listed | Bethesda | Maryland | — | — |
| Not listed | Edina | Minnesota | — | — |
| Not listed | Rochester | Minnesota | — | — |
| Not listed | Olive Branch | Mississippi | — | — |
| Not listed | Port Gibson | Mississippi | — | — |
| Not listed | St Louis | Missouri | — | — |
| Not listed | Butte | Montana | — | — |
| Not listed | Las Vegas | Nevada | — | — |
| Not listed | Williamsville | New York | — | — |
| Not listed | Winston-Salem | North Carolina | — | — |
| Not listed | Cleveland | Ohio | — | — |
| Not listed | Oklahoma City | Oklahoma | — | — |
| Not listed | Warwick | Rhode Island | — | — |
| Not listed | Greer | South Carolina | — | — |
| Not listed | Summerville | South Carolina | — | — |
| Not listed | Kingsport | Tennessee | — | — |
| Not listed | Dallas (2 Locations) | Texas | — | — |
| Not listed | Fort Worth | Texas | — | — |
| Not listed | Houston | Texas | — | — |
| Not listed | Bountiful | Utah | — | — |
| Not listed | Marion | Utah | — | — |
| Not listed | Salt Lake City | Utah | — | — |
| Not listed | Renton | Washington | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 41 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01730040, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 31, 2015 · Synced Oct 16, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01730040 live on ClinicalTrials.gov.