Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma
Public ClinicalTrials.gov record NCT01730950. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Randomized Phase II Trial of Concurrent Bevacizumab and Re-Irradiation Versus Bevacizumab Alone as Treatment for Recurrent Glioblastoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This randomized phase II trial studies how well bevacizumab with or without radiation therapy works in treating patients with recurrent glioblastoma. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry cancer-killing substances to them. Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. It is not yet know whether bevacizumab is more effective with or without radiation therapy in treating patients with recurrent glioblastoma
Study identification
- NCT ID
- NCT01730950
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 182 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 20, 2012 (Actual)
- Primary completion
- Sep 3, 2018 (Actual)
- Completion
- Dec 22, 2022 (Actual)
- Last update posted
- Dec 29, 2022
2012 – 2022
United States locations
- U.S. sites
- 31
- U.S. states
- 21
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Arizona Oncology Services Foundation | Phoenix | Arizona | 85013 | — |
| Arizona Oncology-Deer Valley Center | Phoenix | Arizona | 85027 | — |
| John Muir Medical Center | Walnut Creek | California | 94598 | — |
| Yale University | New Haven | Connecticut | 06520-8032 | — |
| University of Miami Miller School of Medicine-Sylvester Cancer Center | Miami | Florida | 33136 | — |
| Queen's Medical Center | Honolulu | Hawaii | 96813 | — |
| Radiation Oncology Associates PC | Fort Wayne | Indiana | 46804 | — |
| IU Health Methodist Hospital | Indianapolis | Indiana | 46202 | — |
| Memorial Hospital of South Bend | South Bend | Indiana | 46601 | — |
| Norton Health Care Pavilion - Downtown | Louisville | Kentucky | 40202 | — |
| Maine Medical Center- Scarborough Campus | Scarborough | Maine | 04074 | — |
| Lowell General Hospital | Lowell | Massachusetts | 01854 | — |
| University of Michigan University Hospital | Ann Arbor | Michigan | 48109 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Nebraska Methodist Hospital | Omaha | Nebraska | 68114 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| Cone Health Cancer Center | Greensboro | North Carolina | 27403 | — |
| Summa Akron City Hospital | Akron | Ohio | 44304 | — |
| Summa Barberton Hospital | Barberton | Ohio | 44203 | — |
| Lancaster General Hospital | Lancaster | Pennsylvania | 17604 | — |
| Radiation Therapy Oncology Group | Philadelphia | Pennsylvania | 19103 | — |
| Allegheny Cancer Center at Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555-0565 | — |
| North Star Lodge Cancer Center at Yakima Valley Memorial Hospital | Yakima | Washington | 98902 | — |
| Saint Vincent Hospital | Green Bay | Wisconsin | 54301 | — |
| Saint Mary's Hospital | Green Bay | Wisconsin | 54303 | — |
| Bay Area Medical Center | Marinette | Wisconsin | 54143 | — |
| Door County Cancer Center | Sturgeon Bay | Wisconsin | 54235-1495 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01730950, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 29, 2022 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01730950 live on ClinicalTrials.gov.