MIRACLE EF Clinical Study
Public ClinicalTrials.gov record NCT01735916. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is looking at whether the electrical treatment provided by a special type of pacemaker called a Cardiac Resynchronization Therapy (CRT) pacemaker may keep a patient's heart failure from getting worse. When the lower heart chambers (i.e. ventricles) are electrically paced to beat together by the CRT pacemaker, blood may be pumped to the body more efficiently. The CRT pacemaker being studied in this clinical trial is approved by the US Food and Drug Administration (FDA) for patients with moderate to severe heart failure, whose hearts pump blood inefficiently. In the MIRACLE EF study, patients who have heart failure with slightly less inefficient hearts will be observed to see if the electrical pacing treatment is better than not getting the treatment. This study is being conducted to support FDA approval of this type of pacemaker for people whose heart failure is less inefficient.
Study identification
- NCT ID
- NCT01735916
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 44 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2012 (Type not available)
- Primary completion
- Mar 2014 (Actual)
- Completion
- Mar 2014 (Actual)
- Last update posted
- Nov 6, 2017
2012 – 2014
United States locations
- U.S. sites
- 69
- U.S. states
- 29
- U.S. cities
- 65
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| John Muir Medical Center, Cor Cardiovascular Specialists, John Muir Medical Center (Concord), John Muir Cardiovascular Institute, Contra Costa Cardiology | Concord | California | 94520 | — |
| Scripps Clinic Torrey Pines, Scripps Green Hospital | La Jolla | California | 92037 | — |
| VA Greater Los Angeles Healthcare System | Los Angeles | California | 90073 | — |
| Eisenhower Desert Cardiology Center, Eisenhower Medical Center Hospital | Rancho Mirage | California | 92270 | — |
| Los Robles Medical Center | Thousand Oaks | California | 91360 | — |
| Colorado Health Medical Group, Memorial Hospital Colorado Springs | Colorado Springs | Colorado | 80909 | — |
| Hartford Hospital | Hartford | Connecticut | 06106 | — |
| Bradenton Cardiology, Manatee Memorial Hospital | Bradenton | Florida | 34205 | — |
| Melbourne Internal Medicine Associates / Century Research Associates, Holmes Regional Medical Center Hospital | Melbourne | Florida | 32901 | — |
| Aventura Hospital and Medical Center, Hospital Corporation of America (Aventura), Hospital Corporation of America (Miami) | Miami | Florida | 33137 | — |
| Emory University Hospital Midtown | Atlanta | Georgia | 30308 | — |
| WellStar Cobb Hospital, WellStar Kennestone Hospital | Marietta | Georgia | 30060 | — |
| Advocate Medical Group, Midwest Heart Specialists (Elmhurst), Elmhurst Memorial Hospital | Elmhurst | Illinois | 60126 | — |
| Advocate Christ Medical Center | Oak Lawn | Illinois | 60453 | — |
| Prairie Education and Research Cooperative (Springfield IL), Prairie Education Research Consultants, St. John's Hospital (Springfield IL) | Springfield | Illinois | 62701 | — |
| McFarland Clinic PC | Ames | Iowa | 50010 | — |
| Cardiovascular Medicine PC (Davenport IA), Trinity (Rock Island), Midwest Cardiovascular Research Foundation, Trinity Bettendorf Hospital | Davenport | Iowa | 52803 | — |
| Midwest Cardiology Associates PA, Menorah Medical Center, Centerpoint Medical Center, Overland Park Regional Medical Center Hospital | Overland Park | Kansas | 66209 | — |
| Lahey Hospital & Medical Center | Burlington | Massachusetts | 01805 | — |
| Sparrow Clinical Research Institute, McLaren Hospital | Lansing | Michigan | 48910 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| HealthEast HeartCare Clinic at Saint John's | Maplewood | Minnesota | 55109 | — |
| Minneapolis Heart Institute Foundation | Minneapolis | Minnesota | 55407 | — |
| The Cardiovascular Center, University of Minnesota Medical Center Fairview | Minneapolis | Minnesota | 55455 | — |
| North Memorial Heart and Vascular Institute, North Memorial Medical Center | Robbinsdale | Minnesota | 55422 | — |
| CentraCare Heart & Vascular Center | Saint Cloud | Minnesota | 56303 | — |
| Minneapolis Heart Institute Foundation, Mercy Hospital (Coon Rapids MN), Unity Hospital, United Hospital, Abbott Northwestern Hospital | Saint Paul | Minnesota | 55102 | — |
| Missouri Cardiovascular Specialists, Boone Hospital Center | Columbia | Missouri | 65201 | — |
| Cardiovascular Consultants, P.C., Saint Luke's Hospital, Mid America Heart Institute (MAHI) | Kansas City | Missouri | 64111 | — |
| Mercy Heart and Vascular Clinic, Mercy Hospital St. Louis | St Louis | Missouri | 63141 | — |
| Glacier View Research Institute Cardiology, Duplicate Glacier View Research Institute Hospital | Kalispell | Montana | 59901 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| New Mexico Heart Institute PA | Albuquerque | New Mexico | 87102 | — |
| Buffalo Heart Group LLP, Buffalo Heart Group LLC-Cheektowaga, Mercy Hospital of Buffalo | Buffalo | New York | 14215 | — |
| Stony Brook Islandia Clinic, Stony Brook Hauppauge, Stony Brook University Medical Center | Stony Brook | New York | 11794 | — |
| Duke University Medical Center (DUMC) | Durham | North Carolina | 27705 | — |
| Durham VA Medical Center, Duke University Medical Center | Durham | North Carolina | 27710 | — |
| FirstHealth Cardiology Services, FirstHealth Moore Regional Hospital | Pinehurst | North Carolina | 28374 | — |
| Forsyth Medical Center, Novant Clinical Research Institute | Winston-Salem | North Carolina | 27103 | — |
| Sanford Medical Center | Fargo | North Dakota | 58102 | — |
| Lindner Research Center, The Christ Hospital | Cincinnati | Ohio | 45219 | — |
| Ohio State University, Ohio State University Medical Center The Richard M Ross Heart Hospital | Columbus | Ohio | 43210 | — |
| Mercy Hospital Fairfield, Mercy Hospital Anderson, The Jewish Hospital | Fairfield | Ohio | 45014 | — |
| Integris Baptist Medical Center | Oklahoma City | Oklahoma | 73112 | — |
| Samaritan Health Services | Corvallis | Oregon | 97330 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Lehigh Valley Hospital | Allentown | Pennsylvania | 18103 | — |
| Mercer Bucks Cardiology, Saint Mary Medical Center, Arrhythmia Institute Hospital | Newtown | Pennsylvania | 18940 | — |
| University of Pittsburgh Medical Center UPMC Presbyterian | Pittsburgh | Pennsylvania | 15213 | — |
| Cardiac Diagnostic Associates, York Hospital | York | Pennsylvania | 17405 | — |
| Pee Dee Cardiology, McLeod Regional Medical Center | Florence | South Carolina | 29506 | — |
| Arrhythmia Consultants (Greenville SC), Greenville Memorial Hospital | Greenville | South Carolina | 29605 | — |
| Cardiology Consultants PA, Spartanburg Regional Hospital | Spartanburg | South Carolina | 29303 | — |
| Wellmont CVA Heart Institute, Wellmont Holston Valley Medical Center | Kingsport | Tennessee | 37660 | — |
| Centennial Heart Cardiovascular Consultants LLC | Nashville | Tennessee | 37203 | — |
| Saint Thomas Research Institute LLC, Baptist Hospital | Nashville | Tennessee | 37205 | — |
| Amarillo Heart Group, Northwest Texas Hospital | Amarillo | Texas | 79106 | — |
| Cardiology Center of Amarillo, Northwest Texas Hospital | Amarillo | Texas | 79106 | — |
| HeartPlace Cardiology Research, Baylor Heart & Vascular Hospital | Dallas | Texas | 75226 | — |
| Methodist DeBakey Cardiology Associates, The Methodist Hospital | Houston | Texas | 77030 | — |
| Baylor Research Institute (Plano TX), Legacy Heart Center | Plano | Texas | 75204 | — |
| Scott & White Hospital | Temple | Texas | 76508 | — |
| Fletcher Allen Medical Center | Burlington | Vermont | 05405 | — |
| University of Virginia (UVA) Medical Center | Charlottesville | Virginia | 22908 | — |
| Centra Medical Group Stroobants Cardiovascular Center, Centra Lynchburg General Hospital | Lynchburg | Virginia | 24501 | — |
| Richmond Cardiology Associates, Bon Secours Memorial Regional Medical Center | Mechanicsville | Virginia | 23116 | — |
| Sentara Cardiovascular Specialist, Sentara Williamsburg Regional Medical Center, Sentara Norfolk General Hospital, Sentara Virginia Beach General Hospital | Norfolk | Virginia | 23507 | — |
| Harborview Medical Center, University of Washington (UW) Medical Center | Seattle | Washington | 98195 | — |
| Aurora Cardiovascular Services, Aurora Sinai Medical Center, Aurora Saint Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01735916, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 6, 2017 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01735916 live on ClinicalTrials.gov.