Efficacy and Safety of Inotersen in Familial Amyloid Polyneuropathy
Public ClinicalTrials.gov record NCT01737398. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2/3 Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of ISIS 420915 in Patients With Familial Amyloid Polyneuropathy (NEURO-TTR Study)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of inotersen given for 65 weeks in participants with Familial Amyloid Polyneuropathy (FAP).
Study identification
- NCT ID
- NCT01737398
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 173 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 82 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 15, 2013 (Actual)
- Primary completion
- Mar 3, 2017 (Actual)
- Completion
- Nov 7, 2017 (Actual)
- Last update posted
- Jul 17, 2019
2013 – 2017
United States locations
- U.S. sites
- 9
- U.S. states
- 8
- U.S. cities
- 8
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of California, Irvine | Orange | California | 92868 | — |
| Indiana University School of Medicine | Indianapolis | Indiana | 46202 | — |
| Johns Hopkins University Bayview Medical Center | Baltimore | Maryland | 21205 | — |
| Boston University School of Medicine - Amyloid Treatment & Research Program | Boston | Massachusetts | 02118 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Mount Sinai Medical Center | New York | New York | 10029 | — |
| Columbia University Medical Center - The Neurological Institute | New York | New York | 10032 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Penn Presbyterian Medical Center | Philadelphia | Pennsylvania | 19104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01737398, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 17, 2019 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01737398 live on ClinicalTrials.gov.