A Phase 3 Study to Evaluate the Efficacy of Lifitegrast in Subjects With Dry Eye
Public ClinicalTrials.gov record NCT01743729. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-Masked and Placebo-Controlled Study Evaluating the Efficacy of a 5.0% Concentration of Lifitegrast Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye Currently Using Artificial Tears (OPUS-2)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to evaluate the safety and efficacy of lifitegrast ophthalmic solution compared to placebo in the treatment of dry eye.
Study identification
- NCT ID
- NCT01743729
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 720 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 7, 2012 (Actual)
- Primary completion
- Oct 1, 2013 (Actual)
- Completion
- Oct 1, 2013 (Actual)
- Last update posted
- Jun 23, 2021
2012 – 2013
United States locations
- U.S. sites
- 31
- U.S. states
- 13
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| OPUS-2 Investigational Site | Artesia | California | 90701 | — |
| OPUS-2 Investigational Site | Hemet | California | 92545 | — |
| OPUS-2 Investigational Site | Lancaster | California | 93534 | — |
| OPUS-2 Investigational Site | Mission Hills | California | 91345 | — |
| OPUS-2 Investigational Site | Montebello | California | 90640 | — |
| OPUS-2 Investigational Site | Newport Beach | California | 92663 | — |
| OPUS-2 Investigational Site | Petaluma | California | 94954 | — |
| OPUS-2 Investigational SIte | Rancho Cordova | California | 95670 | — |
| OPUS-2 Investigational Site | Danbury | Connecticut | 06810 | — |
| OPUS-2 Investigational Site | Fort Myers | Florida | 33901 | — |
| OPUS-2 Investigational Site | Hoffman Estates | Illinois | 60169 | — |
| OPUS-2 Investigational Site | Indianapolis | Indiana | 46260 | — |
| OPUS-2 Investigational Site | New Albany | Indiana | 47150 | — |
| OPUS-2 Investigational Site | Lexington | Kentucky | 40509 | — |
| OPUS-2 Investigational Site | Saint Paul | Minnesota | 55082 | — |
| OPUS-2 Investigational Site | Chesterfield | Missouri | 63017 | — |
| OPUS-2 Investigational Site | Des Peres | Missouri | 63131 | — |
| OPUS-2 Investigational Site | Independence | Missouri | 64055 | — |
| OPUS-2 Investigational Site | Kansas City | Missouri | 64111 | — |
| OPUS-2 Investigational Site | Washington | Missouri | 63090 | — |
| OPUS-2 Investigational Site | New York | New York | 10016 | — |
| OPUS-2 Investigational Site | New York | New York | 10036 | — |
| OPUS-2 Investigational Site | Wantagh | New York | 11793 | — |
| OPUS-2 Investigational Site | Cleveland | Ohio | 44115 | — |
| OPUS-2 Investigational Site | Philadelphia | Pennsylvania | 19148 | — |
| OPUS-2 Investigational Site | Houston | Texas | 77034 | — |
| OPUS-2 Investigational Site | Houston | Texas | 77055 | — |
| OPUS-2 Investigational Site | League City | Texas | 77573 | — |
| OPUS-2 Investigational Site | San Antonio | Texas | 78209 | — |
| OPUS-2 Investigational Site | San Antonio | Texas | 78229 | — |
| OPUS-2 Investigational Site | Norfolk | Virginia | 23502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01743729, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 23, 2021 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01743729 live on ClinicalTrials.gov.