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Completed No phase listed Observational

Prospective, Multiconfiguration Study to Assess Functional Performance of Primary Total Knee Arthroplasty System

ClinicalTrials.gov ID: NCT01746524

Public ClinicalTrials.gov record NCT01746524. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 24, 2026, 12:15 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Prospective, Single Arm Multiconfiguration Investigation to Assess Functional Performance of Attune™ Primary Total Knee Arthroplasty System

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This post-marketing investigation will evaluate the functional knee performance of Subjects who have undergone primary total knee arthroplasty (TKA). Data from Subjects who receive one of four contemporary knee configurations will be pooled to establish a contemporary dataset. The primary objective of this study is to evaluate the pre-operative (approximately -90 to -1 day before surgery) to minimum one year (approximately 304 to 668 days) postoperative functional performance improvement for the Attune™ primary, cemented TKA system as measured by the activities of daily living (ADL)subscore of the Knee Osteoarthritis Outcomes Score (KOOS)questionnaire (KOOS-ADL sub-score). This will be carried out for all four implant configurations: cruciate retaining fixed bearing (Attune™ CR FB), cruciate retaining rotating platform (Attune™ CR RP), posterior stabilized fixed bearing (Attune™ PS FB), and posterior stabilized rotating platform (Attune™ PS RP).

Study identification

NCT ID
NCT01746524
Recruitment status
Completed
Study type
Observational
Phase
Not listed
Lead sponsor
DePuy Orthopaedics
Industry
Enrollment
1,138 participants

Conditions and interventions

Conditions

Interventions

Device

Eligibility (public fields only)

Age range
22 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 31, 2012
Primary completion
Mar 4, 2018
Completion
Mar 4, 2018
Last update posted
Apr 10, 2019

2012 – 2018

United States locations

U.S. sites
9
U.S. states
8
U.S. cities
9
Facility City State ZIP Site status
Orthopaedic Specialty Institute Orange California 92868
UCSD Medical Center San Diego California 92103
Orhopaedic Center of the Rockies Fort Collins Colorado 80525
The Arthroplasty Foundation Louisville Kentucky 40215
Hip and Knee Research of Nevada Las Vegas Nevada 89128
Dartmouth Medical School/Dartmouth-Hitchcock Medical Center Lebanon New Hampshire 03765
Cardinal Orthopaedic Institute Columbus Ohio 43213
Anderson Orthopaedic Research Institute Alexandria Virginia 22307
Swedish Orthopedic Institute Seattle Washington 98122

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01746524, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 10, 2019 · Synced Sep 24, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01746524 live on ClinicalTrials.gov.

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