ClinicalTrials.gov record
Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk
ClinicalTrials.gov ID: NCT01764633
Public ClinicalTrials.gov record NCT01764633. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing the Impact of Additional LDL-Cholesterol Reduction on Major Cardiovascular Events When Evolocumab (AMG 145) is Used in Combination With Statin Therapy In Patients With Clinically Evident Cardiovascular Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective was to evaluate the effect of treatment with evolocumab, compared with placebo, on the risk for cardiovascular death, myocardial infarction, stroke, hospitalization for unstable angina, or coronary revascularization, whichever occurs first, in patients with clinically evident cardiovascular disease.
Study identification
- NCT ID
- NCT01764633
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 27,564 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 8, 2013 (Actual)
- Primary completion
- Nov 11, 2016 (Actual)
- Completion
- Nov 11, 2016 (Actual)
- Last update posted
- May 28, 2024
2013 – 2016
United States locations
- U.S. sites
- 326
- U.S. states
- 45
- U.S. cities
- 278
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Birmingham | Alabama | 35235 | — |
| Research Site | Birmingham | Alabama | 35294 | — |
| Research Site | Huntsville | Alabama | 35801 | — |
| Research Site | Mobile | Alabama | 36608 | — |
| Research Site | Anchorage | Alaska | 99508 | — |
| Research Site | Glendale | Arizona | 85306 | — |
| Research Site | Phoenix | Arizona | 85015 | — |
| Research Site | Phoenix | Arizona | 85018 | — |
| Research Site | Phoenix | Arizona | 85054 | — |
| Research Site | Tucson | Arizona | 85712 | — |
| Research Site | Tucson | Arizona | 85723 | — |
| Research Site | Alhambra | California | 91801 | — |
| Research Site | Banning | California | 92220 | — |
| Research Site | Beverly Hills | California | 90211 | — |
| Research Site | Encino | California | 91436 | — |
| Research Site | Escondido | California | 92029 | — |
| Research Site | Glendale | California | 91204 | — |
| Research Site | Harbor City | California | 90710 | — |
| Research Site | Huntington Beach | California | 92646 | — |
| Research Site | Laguna Hills | California | 92653 | — |
| Research Site | Long Beach | California | 90807 | — |
| Research Site | Long Beach | California | 90822 | — |
| Research Site | Los Alamitos | California | 90720 | — |
| Research Site | Los Angeles | California | 90033 | — |
| Research Site | Los Angeles | California | 90048 | — |
| Research Site | Newport Beach | California | 92663 | — |
| Research Site | Oceanside | California | 92056 | — |
| Research Site | Oxnard | California | 93030 | — |
| Research Site | Palm Springs | California | 92262 | — |
| Research Site | Roseville | California | 95661 | — |
| Research Site | Sacramento | California | 95816 | — |
| Research Site | San Diego | California | 92103 | — |
| Research Site | San Diego | California | 92161 | — |
| Research Site | San Pedro | California | 90732 | — |
| Research Site | Santa Ana | California | 92704 | — |
| Research Site | Tarzana | California | 91356 | — |
| Research Site | Thousand Oaks | California | 91360 | — |
| Research Site | Torrance | California | 90502 | — |
| Research Site | Torrance | California | 90503 | — |
| Research Site | Valley Village | California | 91607 | — |
| Research Site | Aurora | Colorado | 80012 | — |
| Research Site | Colorado Springs | Colorado | 80907 | — |
| Research Site | Colorado Springs | Colorado | 80909 | — |
| Research Site | Denver | Colorado | 80218 | — |
| Research Site | Greeley | Colorado | 80631 | — |
| Research Site | Littleton | Colorado | 80120 | — |
| Research Site | Longmont | Colorado | 80501 | — |
| Research Site | Bridgeport | Connecticut | 06610 | — |
| Research Site | Newark | Delaware | 19718 | — |
| Research Site | Seaford | Delaware | 19973 | — |
| Research Site | Wilmington | Delaware | 19803 | — |
| Research Site | Washington D.C. | District of Columbia | 20037 | — |
| Research Site | Atlantis | Florida | 33462 | — |
| Research Site | Aventura | Florida | 33180 | — |
| Research Site | Bay Pines | Florida | 33744 | — |
| Research Site | Boynton Beach | Florida | 33472 | — |
| Research Site | Bradenton | Florida | 34205 | — |
| Research Site | Clearwater | Florida | 33756 | — |
| Research Site | Crystal River | Florida | 34429 | — |
| Research Site | Daytona Beach | Florida | 32117 | — |
| Research Site | Deerfield Beach | Florida | 33442 | — |
| Research Site | Delray Beach | Florida | 33484 | — |
| Research Site | Edgewater | Florida | 32141 | — |
| Research Site | Fleming Island | Florida | 32003 | — |
| Research Site | Fort Lauderdale | Florida | 33308 | — |
| Research Site | Hollywood | Florida | 33021 | — |
| Research Site | Jacksonville | Florida | 32216 | — |
| Research Site | Jacksonville Beach | Florida | 32250 | — |
| Research Site | Lakeland | Florida | 33805 | — |
| Research Site | Largo | Florida | 33777 | — |
| Research Site | Melbourne | Florida | 32901 | — |
| Research Site | Miami | Florida | 33144 | — |
| Research Site | Miami | Florida | 33155 | — |
| Research Site | Miami | Florida | 33173 | — |
| Research Site | New Port Richey | Florida | 34653 | — |
| Research Site | Orlando | Florida | 32806 | — |
| Research Site | Palm Harbor | Florida | 34684 | — |
| Research Site | Pembroke Pines | Florida | 33024 | — |
| Research Site | Pembroke Pines | Florida | 33028 | — |
| Research Site | Pensacola | Florida | 32501 | — |
| Research Site | Ponte Vedra | Florida | 32081 | — |
| Research Site | Port Charlotte | Florida | 33952 | — |
| Research Site | Safety Harbor | Florida | 34695 | — |
| Research Site | Sanford | Florida | 32771 | — |
| Research Site | Sarasota | Florida | 34232 | — |
| Research Site | Sarasota | Florida | 34239 | — |
| Research Site | St. Petersburg | Florida | 33709 | — |
| Research Site | St. Petersburg | Florida | 33713 | — |
| Research Site | Tampa | Florida | 33614 | — |
| Research Site | Wellington | Florida | 33449 | — |
| Research Site | West Palm Beach | Florida | 33401 | — |
| Research Site | Athens | Georgia | 30606 | — |
| Research Site | Atlanta | Georgia | 30342 | — |
| Research Site | Augusta | Georgia | 30909 | — |
| Research Site | Dunwoody | Georgia | 30338 | — |
| Research Site | East Point | Georgia | 30344 | — |
| Research Site | Eatonton | Georgia | 31024 | — |
| Research Site | Gainesville | Georgia | 30501 | — |
| Research Site | Macon | Georgia | 31201 | — |
| Research Site | Savannah | Georgia | 31406 | — |
| Research Site | Suwanee | Georgia | 30024 | — |
| Research Site | Boise | Idaho | 83704 | — |
| Research Site | Boise | Idaho | 83706 | — |
| Research Site | Coeur d'Alene | Idaho | 83814 | — |
| Research Site | Meridian | Idaho | 83642 | — |
| Research Site | Nampa | Idaho | 83686 | — |
| Research Site | Addison | Illinois | 60101 | — |
| Research Site | Belleville | Illinois | 62220 | — |
| Research Site | Chicago | Illinois | 60616 | — |
| Research Site | Hazel Crest | Illinois | 60429 | — |
| Research Site | Jerseyville | Illinois | 62052 | — |
| Research Site | Quincy | Illinois | 62301 | — |
| Research Site | Evansville | Indiana | 47714 | — |
| Research Site | Indianapolis | Indiana | 46227 | — |
| Research Site | Indianapolis | Indiana | 46237 | — |
| Research Site | Indianapolis | Indiana | 46260 | — |
| Research Site | Munster | Indiana | 46321 | — |
| Research Site | Valparaiso | Indiana | 46383 | — |
| Research Site | Ames | Iowa | 50010 | — |
| Research Site | Des Moines | Iowa | 50266 | — |
| Research Site | Iowa City | Iowa | 52242 | — |
| Research Site | Waterloo | Iowa | 50702 | — |
| Research Site | Hutchinson | Kansas | 67502 | — |
| Research Site | Kansas City | Kansas | 66160 | — |
| Research Site | Overland Park | Kansas | 66210 | — |
| Research Site | Wichita | Kansas | 67203 | — |
| Research Site | Wichita | Kansas | 67214 | — |
| Research Site | Lexington | Kentucky | 40504 | — |
| Research Site | Owensboro | Kentucky | 42303 | — |
| Research Site | Baton Rouge | Louisiana | 70808 | — |
| Research Site | Covington | Louisiana | 70433 | — |
| Research Site | Hammond | Louisiana | 70403 | — |
| Research Site | Lafayette | Louisiana | 70508 | — |
| Research Site | Metairie | Louisiana | 70006 | — |
| Research Site | Monroe | Louisiana | 71203 | — |
| Research Site | Natchitoches | Louisiana | 71457 | — |
| Research Site | Slidell | Louisiana | 70458 | — |
| Research Site | Auburn | Maine | 04210 | — |
| Research Site | Bangor | Maine | 04401 | — |
| Research Site | Biddeford | Maine | 04005 | — |
| Research Site | Portland | Maine | 04101 | — |
| Research Site | Annapolis | Maryland | 21401 | — |
| Research Site | Baltimore | Maryland | 21201 | — |
| Research Site | Baltimore | Maryland | 21204 | — |
| Research Site | Baltimore | Maryland | 21236 | — |
| Research Site | Baltimore | Maryland | 21237 | — |
| Research Site | Charlotte Hall | Maryland | 20622 | — |
| Research Site | Columbia | Maryland | 21044 | — |
| Research Site | Columbia | Maryland | 21045 | — |
| Research Site | Hollywood | Maryland | 20636 | — |
| Research Site | Salisbury | Maryland | 21804 | — |
| Research Site | Towson | Maryland | 21204 | — |
| Research Site | Ayer | Massachusetts | 01432 | — |
| Research Site | Billerica | Massachusetts | 01821 | — |
| Research Site | Fall River | Massachusetts | 02720 | — |
| Research Site | Haverhill | Massachusetts | 01830 | — |
| Research Site | Hyannis | Massachusetts | 02601 | — |
| Research Site | Newton | Massachusetts | 02459 | — |
| Research Site | Quincy | Massachusetts | 02169 | — |
| Research Site | Springfield | Massachusetts | 01199 | — |
| Research Site | Watertown | Massachusetts | 02472 | — |
| Research Site | Ann Arbor | Michigan | 48106 | — |
| Research Site | Dearborn | Michigan | 48124 | — |
| Research Site | Flint | Michigan | 48532 | — |
| Research Site | Grandville | Michigan | 49418 | — |
| Research Site | Lansing | Michigan | 48912 | — |
| Research Site | Muskegon | Michigan | 49444 | — |
| Research Site | Novi | Michigan | 48374 | — |
| Research Site | Saginaw | Michigan | 48601 | — |
| Research Site | Saginaw | Michigan | 48604 | — |
| Research Site | Traverse City | Michigan | 49684 | — |
| Research Site | Minneapolis | Minnesota | 55417 | — |
| Research Site | Saint Cloud | Minnesota | 56303 | — |
| Research Site | Saint Paul | Minnesota | 55102 | — |
| Research Site | Olive Branch | Mississippi | 38654 | — |
| Research Site | Tupelo | Mississippi | 38801 | — |
| Research Site | Columbia | Missouri | 65212 | — |
| Research Site | Jefferson City | Missouri | 65109 | — |
| Research Site | Kansas City | Missouri | 64128 | — |
| Research Site | St Louis | Missouri | 63117 | — |
| Research Site | St Louis | Missouri | 63128 | — |
| Research Site | Billings | Montana | 59101 | — |
| Research Site | Billings | Montana | 59102 | — |
| Research Site | Great Falls | Montana | 59405 | — |
| Research Site | Kalispell | Montana | 59901 | — |
| Research Site | Missoula | Montana | 59802 | — |
| Research Site | Lincoln | Nebraska | 68506 | — |
| Research Site | Omaha | Nebraska | 68131 | — |
| Research Site | Las Vegas | Nevada | 89128 | — |
| Research Site | Elizabeth | New Jersey | 07202 | — |
| Research Site | Voorhees Township | New Jersey | 08043 | — |
| Research Site | Westwood | New Jersey | 07675 | — |
| Research Site | Albany | New York | 12208 | — |
| Research Site | Buffalo | New York | 14203 | — |
| Research Site | Buffalo | New York | 14215 | — |
| Research Site | Cortlandt Manor | New York | 10567 | — |
| Research Site | Kingston | New York | 12401 | — |
| Research Site | New Hyde Park | New York | 11042 | — |
| Research Site | New Windsor | New York | 12553 | — |
| Research Site | New York | New York | 10021 | — |
| Research Site | New York | New York | 10029 | — |
| Research Site | New York | New York | 10033 | — |
| Research Site | New York | New York | 10036 | — |
| Research Site | Rochester | New York | 14609 | — |
| Research Site | Stony Brook | New York | 11794 | — |
| Research Site | Syracuse | New York | 13202 | — |
| Research Site | Troy | New York | 12180 | — |
| Research Site | West Seneca | New York | 14224 | — |
| Research Site | Williamsville | New York | 14221 | — |
| Research Site | Asheville | North Carolina | 28801 | — |
| Research Site | Asheville | North Carolina | 28805 | — |
| Research Site | Calabash | North Carolina | 28467 | — |
| Research Site | Cary | North Carolina | 27518 | — |
| Research Site | Charlotte | North Carolina | 28204 | — |
| Research Site | Charlotte | North Carolina | 28277 | — |
| Research Site | Durham | North Carolina | 27710 | — |
| Research Site | Greensboro | North Carolina | 27408 | — |
| Research Site | Hickory | North Carolina | 28601 | — |
| Research Site | High Point | North Carolina | 27262 | — |
| Research Site | Lenoir | North Carolina | 28645 | — |
| Research Site | Mooresville | North Carolina | 28117 | — |
| Research Site | Raleigh | North Carolina | 27609 | — |
| Research Site | Statesville | North Carolina | 28625 | — |
| Research Site | Tabor City | North Carolina | 28463 | — |
| Research Site | Wilmington | North Carolina | 28401 | — |
| Research Site | Winston-Salem | North Carolina | 27103 | — |
| Research Site | Winston-Salem | North Carolina | 27127 | — |
| Research Site | Fargo | North Dakota | 58122 | — |
| Research Site | Grand Forks | North Dakota | 58201 | — |
| Research Site | Canton | Ohio | 44710 | — |
| Research Site | Cincinnati | Ohio | 45219 | — |
| Research Site | Cincinnati | Ohio | 45224 | — |
| Research Site | Cleveland | Ohio | 44195 | — |
| Research Site | Columbus | Ohio | 43201 | — |
| Research Site | Columbus | Ohio | 43215 | — |
| Research Site | Dayton | Ohio | 45414 | — |
| Research Site | Elyria | Ohio | 44035 | — |
| Research Site | Garfield Heights | Ohio | 44125 | — |
| Research Site | Marion | Ohio | 43302 | — |
| Research Site | Sandusky | Ohio | 44870 | — |
| Research Site | Springfield | Ohio | 45505 | — |
| Research Site | Toledo | Ohio | 43608 | — |
| Research Site | Toledo | Ohio | 43615 | — |
| Research Site | Toledo | Ohio | 43623 | — |
| Research Site | Westlake | Ohio | 44145 | — |
| Research Site | Willoughby | Ohio | 44094 | — |
| Research Site | Oklahoma City | Oklahoma | 73135 | — |
| Research Site | Pryor | Oklahoma | 74362 | — |
| Research Site | Tulsa | Oklahoma | 74133 | — |
| Research Site | Bend | Oregon | 97701 | — |
| Research Site | Portland | Oregon | 97225 | — |
| Research Site | Portland | Oregon | 97239 | — |
| Research Site | Abington | Pennsylvania | 19001 | — |
| Research Site | Altoona | Pennsylvania | 16602 | — |
| Research Site | Camp Hill | Pennsylvania | 17011 | — |
| Research Site | Chambersburg | Pennsylvania | 17201 | — |
| Research Site | Feasterville | Pennsylvania | 19053 | — |
| Research Site | Indiana | Pennsylvania | 15701 | — |
| Research Site | Jersey Shore | Pennsylvania | 17740 | — |
| Research Site | Norristown | Pennsylvania | 19401 | — |
| Research Site | Philadelphia | Pennsylvania | 19104 | — |
| Research Site | Philadelphia | Pennsylvania | 19107 | — |
| Research Site | Philadelphia | Pennsylvania | 19152 | — |
| Research Site | Pittsburgh | Pennsylvania | 15206 | — |
| Research Site | Sellersville | Pennsylvania | 18960 | — |
| Research Site | Uniontown | Pennsylvania | 15401 | — |
| Research Site | York | Pennsylvania | 17405 | — |
| Research Site | Cranston | Rhode Island | 02920 | — |
| Research Site | Cumberland | Rhode Island | 02864 | — |
| Research Site | Johnston | Rhode Island | 02919 | — |
| Research Site | Pawtucket | Rhode Island | 02860 | — |
| Research Site | Anderson | South Carolina | 29621 | — |
| Research Site | Charleston | South Carolina | 29407 | — |
| Research Site | Charleston | South Carolina | 29425 | — |
| Research Site | Columbia | South Carolina | 29204 | — |
| Research Site | Fountain Inn | South Carolina | 29644 | — |
| Research Site | Moncks Corner | South Carolina | 29461 | — |
| Research Site | Mt. Pleasant | South Carolina | 29464 | — |
| Research Site | North Myrtle Beach | South Carolina | 29582 | — |
| Research Site | Old Point Station | South Carolina | 29707 | — |
| Research Site | Orangeburg | South Carolina | 29118 | — |
| Research Site | Rapid City | South Dakota | 57701 | — |
| Research Site | Germantown | Tennessee | 38138 | — |
| Research Site | Jackson | Tennessee | 38305 | — |
| Research Site | Memphis | Tennessee | 38112 | — |
| Research Site | Nashville | Tennessee | 37203 | — |
| Research Site | Nashville | Tennessee | 37205 | — |
| Research Site | Nashville | Tennessee | 37208 | — |
| Research Site | Tullahoma | Tennessee | 37388 | — |
| Research Site | Arlington | Texas | 76012 | — |
| Research Site | Austin | Texas | 78758 | — |
| Research Site | Dallas | Texas | 75216 | — |
| Research Site | Grapevine | Texas | 76051 | — |
| Research Site | Houston | Texas | 77025 | — |
| Research Site | Houston | Texas | 77030 | — |
| Research Site | Houston | Texas | 77070 | — |
| Research Site | Houston | Texas | 77074 | — |
| Research Site | Kerrville | Texas | 78028 | — |
| Research Site | Longview | Texas | 75605 | — |
| Research Site | Odessa | Texas | 79761 | — |
| Research Site | Plano | Texas | 75023 | — |
| Research Site | Plano | Texas | 75024 | — |
| Research Site | San Antonio | Texas | 78229 | — |
| Research Site | Sugar Land | Texas | 77478 | — |
| Research Site | Tomball | Texas | 77375 | — |
| Research Site | Wichita Falls | Texas | 76301 | — |
| Research Site | Layton | Utah | 84041 | — |
| Research Site | Murray | Utah | 84107 | — |
| Research Site | West Jordan | Utah | 84088 | — |
| Research Site | White River Junction | Vermont | 05009 | — |
| Research Site | Burke | Virginia | 22015 | — |
| Research Site | Danville | Virginia | 24541 | — |
| Research Site | Falls Church | Virginia | 22042 | — |
| Research Site | Hopewell | Virginia | 23860 | — |
| Research Site | Richmond | Virginia | 23219 | — |
| Research Site | Richmond | Virginia | 23294 | — |
| Research Site | Roanoke | Virginia | 24014 | — |
| Research Site | Suffolk | Virginia | 23435 | — |
| Research Site | Virginia Beach | Virginia | 23455 | — |
| Research Site | Federal Way | Washington | 98003 | — |
| Research Site | Seattle | Washington | 98104 | — |
| Research Site | Seattle | Washington | 98195 | — |
| Research Site | Selah | Washington | 98942 | — |
| Research Site | Green Bay | Wisconsin | 54301 | — |
| Research Site | Madison | Wisconsin | 53713 | — |
| Research Site | Marshfield | Wisconsin | 54449 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 958 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01764633, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 28, 2024 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01764633 live on ClinicalTrials.gov.