ECHELON-2: A Comparison of Brentuximab Vedotin and CHP With Standard-of-care CHOP in the Treatment of Patients With CD30-positive Mature T-cell Lymphomas
Public ClinicalTrials.gov record NCT01777152. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Phase 3 Study of Brentuximab Vedotin and CHP (A+CHP) Versus CHOP in the Frontline Treatment of Patients With CD30-positive Mature T-cell Lymphomas
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a double-blind, randomized, multicenter, phase 3 clinical trial to compare the efficacy and safety of brentuximab vedotin in combination with CHP with the standard-of-care CHOP in patients with CD30-positive mature T-cell lymphomas.
Study identification
- NCT ID
- NCT01777152
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 452 participants
Conditions and interventions
Interventions
- brentuximab vedotin Drug
- doxorubicin Drug
- prednisone Drug
- vincristine Drug
- cyclophosphamide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 31, 2013 (Actual)
- Primary completion
- Aug 15, 2018 (Actual)
- Completion
- Oct 2, 2020 (Actual)
- Last update posted
- Nov 30, 2021
2013 – 2020
United States locations
- U.S. sites
- 32
- U.S. states
- 17
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner MD Anderson Cancer Center | Gilbert | Arizona | 85234 | — |
| City of Hope National Medical Center | Duarte | California | 91010-3000 | — |
| Stanford Cancer Center | Stanford | California | 94305 | — |
| Shands Cancer Center / University of Florida | Gainesville | Florida | 32610 | — |
| Orlando Health, Inc. | Orlando | Florida | 32806 | — |
| University of Illinois at Chicago | Chicago | Illinois | 60612 | — |
| Cardinal Bernardin Cancer Center / Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| Holden Comprehensive Cancer Center / University of Iowa | Iowa City | Iowa | 52242 | — |
| University of Kansas Cancer Center | Westwood | Kansas | United States | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Memorial Sloan Kettering Cancer Center - Basking Ridge | Basking Ridge | New Jersey | 07920 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Memorial Sloan Kettering Cancer Center - Commack | Commack | New York | 11725 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10021 | — |
| Columbia University Medical Center | New York | New York | 10022 | — |
| Weill Cornell Medical College | New York | New York | 10065 | — |
| James P. Wilmot Cancer Center / University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Albert Einstein Cancer Center | The Bronx | New York | 10461 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Jewish Hospital, The | Cincinnati | Ohio | 45236 | — |
| Cleveland Clinic, The | Cleveland | Ohio | 44195 | — |
| Mercy Clinic Oncology | Oklahoma City | Oklahoma | 73120 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | United States | — |
| Sarah Cannon Research Institute | Nashville | Tennessee | 30384 | — |
| Charles A. Sammons Cancer Center / Baylor University Medical Center | Dallas | Texas | 75246 | — |
| MD Anderson Cancer Center / University of Texas | Houston | Texas | 77030-4095 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| Virginia Commonwealth University Medical Center | Richmond | Virginia | 23298 | — |
| Benaroya Research Institute/Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| Seattle Cancer Care Alliance / University of Washington | Seattle | Washington | 98109-1023 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 112 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01777152, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 30, 2021 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01777152 live on ClinicalTrials.gov.