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Completed No phase listed Observational Results available

Pediatric Hydroxyurea Phase III Clinical Trial (BABY HUG) Follow-up Observational Study II Protocol

ClinicalTrials.gov ID: NCT01783990

Public ClinicalTrials.gov record NCT01783990. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 6:29 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The BABY HUG Treatment Study was designed to see if treatment with the drug hydroxyurea (also called HU) in children with sickle cell disease could prevent organ damage, especially in the spleen and kidneys. There was also a chance that treatment could prevent painful crises, lung disease, stroke, and blood infection.

Study identification

NCT ID
NCT01783990
Recruitment status
Completed
Study type
Observational
Phase
Not listed
Enrollment
150 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
24 Months to 18 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 30, 2012
Primary completion
Dec 30, 2016
Completion
Dec 30, 2016
Last update posted
Aug 19, 2020

2012 – 2016

United States locations

U.S. sites
14
U.S. states
12
U.S. cities
12
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35233
Children's National Medical Center Center for Cancer and Blood Disorders Washington D.C. District of Columbia 20010
Howard University College of Medicine Washington D.C. District of Columbia 20060
University of Miami School of Medicine Miami Florida 33136
Emory University School of Medicine Atlanta Georgia 30342
Johns Hopkins University School of Medicine Baltimore Maryland 21205
Sinai Hospital of Baltimore Alfred I Coplan Pediatric Hematology Oncology Outpatient Center Baltimore Maryland 21215
Children's Hospital of Michigan/Wayne State University Detroit Michigan 48201
University of Mississippi Medical Center Jackson Mississippi 39216
Downstate Medical Center Brooklyn New York 11203
Duke University Medical Center Durham North Carolina 27710
Medical University of South Carolina Charleston South Carolina 29425
St. Jude Children's Research Hospital Memphis Tennessee 38105
University of Texas Southwestern Medical Center at Dallas Dallas Texas 75390

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01783990, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 19, 2020 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01783990 live on ClinicalTrials.gov.

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