ClinicalTrials.gov record
Erlotinib Hydrochloride or Crizotinib and Chemoradiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer
ClinicalTrials.gov ID: NCT01822496
Public ClinicalTrials.gov record NCT01822496. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Phase II Study of Individualized Combined Modality Therapy for Stage III Non-small Cell Lung Cancer (NSCLC)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This randomized phase II trial studies how well erlotinib hydrochloride or crizotinib with chemoradiation therapy works in treating patients with stage III non-small cell lung cancer. Radiation therapy uses high energy x rays to kill tumor cells. Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. Drugs used in chemotherapy, such as cisplatin, etoposide, paclitaxel, and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whether giving erlotinib hydrochloride is more effective than crizotinib with chemoradiation therapy in treating patients with non-small cell lung cancer.
Study identification
- NCT ID
- NCT01822496
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 59 participants
Conditions and interventions
Conditions
Interventions
- Radiation Therapy Radiation
- Carboplatin Drug
- Cisplatin Drug
- Crizotinib Drug
- Erlotinib Drug
- Etoposide Drug
- Paclitaxel Drug
Radiation · Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 4, 2013 (Actual)
- Primary completion
- Jun 4, 2018 (Actual)
- Completion
- Jun 4, 2018 (Actual)
- Last update posted
- Aug 5, 2019
2013 – 2018
United States locations
- U.S. sites
- 174
- U.S. states
- 36
- U.S. cities
- 140
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham Cancer Center | Birmingham | Alabama | 35233 | — |
| Providence Alaska Medical Center | Anchorage | Alaska | 99508 | — |
| Banner MD Anderson Cancer Center | Gilbert | Arizona | 85234 | — |
| Mayo Clinic in Arizona | Scottsdale | Arizona | 85259 | — |
| AIS Cancer Center at San Joaquin Community Hospital | Bakersfield | California | 93301 | — |
| UC San Diego Moores Cancer Center | La Jolla | California | 92093 | — |
| Fremont - Rideout Cancer Center | Marysville | California | 95901 | — |
| Mercy UC Davis Cancer Center | Merced | California | 95340 | — |
| Stanford Cancer Institute Palo Alto | Palo Alto | California | 94304 | — |
| University of California Davis Comprehensive Cancer Center | Sacramento | California | 95817 | — |
| UCSF Medical Center-Mount Zion | San Francisco | California | 94115 | — |
| Saint Helena Hospital | St. Helena | California | 94574 | — |
| Gene Upshaw Memorial Tahoe Forest Cancer Center | Truckee | California | 96161 | — |
| University of Colorado Hospital | Aurora | Colorado | 80045 | — |
| Rocky Mountain Cancer Centers-Boulder | Boulder | Colorado | 80304 | — |
| Penrose-Saint Francis Healthcare | Colorado Springs | Colorado | 80907 | — |
| UCHealth Memorial Hospital Central | Colorado Springs | Colorado | 80909 | — |
| Poudre Valley Hospital | Fort Collins | Colorado | 80524 | — |
| North Colorado Medical Center | Greeley | Colorado | 80631 | — |
| McKee Medical Center | Loveland | Colorado | 80539 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| The Hospital of Central Connecticut | New Britain | Connecticut | 06050 | — |
| Christiana Care Health System-Christiana Hospital | Newark | Delaware | 19718 | — |
| UM Sylvester Comprehensive Cancer Center at Deerfield Beach | Deerfield Beach | Florida | 33442 | — |
| Memorial Regional Hospital/Joe DiMaggio Children's Hospital | Hollywood | Florida | 33021 | — |
| Baptist MD Anderson Cancer Center | Jacksonville | Florida | 32207 | — |
| Baptist Medical Center South | Jacksonville | Florida | 32258 | — |
| University of Miami Miller School of Medicine-Sylvester Cancer Center | Miami | Florida | 33136 | — |
| UF Cancer Center at Orlando Health | Orlando | Florida | 32806 | — |
| 21st Century Oncology-Palatka | Palatka | Florida | 32177 | — |
| Memorial Hospital West | Pembroke Pines | Florida | 33028 | — |
| Integrated Community Oncology Network-Flager Cancer Center | Saint Augustine | Florida | 32086 | — |
| Robert and Carol Weissman Cancer Center at Martin Health | Stuart | Florida | 34994 | — |
| Moffitt Cancer Center | Tampa | Florida | 33612 | — |
| Emory University Hospital Midtown | Atlanta | Georgia | 30308 | — |
| Emory University Hospital/Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| Emory Saint Joseph's Hospital | Atlanta | Georgia | 30342 | — |
| Northeast Georgia Medical Center-Gainesville | Gainesville | Georgia | 30501 | — |
| Lewis Cancer and Research Pavilion at Saint Joseph's/Candler | Savannah | Georgia | 31405 | — |
| Queen's Medical Center | Honolulu | Hawaii | 96813 | — |
| The Cancer Center of Hawaii-Liliha | Honolulu | Hawaii | 96817 | — |
| Saint Alphonsus Cancer Care Center-Boise | Boise | Idaho | 83706 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Illinois | Chicago | Illinois | 60612 | — |
| University of Chicago Comprehensive Cancer Center | Chicago | Illinois | 60637 | — |
| Decatur Memorial Hospital | Decatur | Illinois | 62526 | — |
| Crossroads Cancer Center | Effingham | Illinois | 62401 | — |
| AMITA Health Alexian Brothers Medical Center | Elk Grove Village | Illinois | 60007 | — |
| Elmhurst Memorial Hospital | Elmhurst | Illinois | 60126 | — |
| AMITA Health Cancer Institute and Outpatient Center | Hinsdale | Illinois | 60521 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| Edward Hospital/Cancer Center | Naperville | Illinois | 60540 | — |
| Edward Hospital/Cancer Center?Plainfield | Plainfield | Illinois | 60585 | — |
| SwedishAmerican Regional Cancer Center/ACT | Rockford | Illinois | 61114 | — |
| Memorial Medical Center | Springfield | Illinois | 62781 | — |
| Saint Vincent Anderson Regional Hospital/Cancer Center | Anderson | Indiana | 46016 | — |
| Radiation Oncology Associates PC | Fort Wayne | Indiana | 46804 | — |
| Parkview Hospital Randallia | Fort Wayne | Indiana | 46805 | — |
| McFarland Clinic PC - Ames | Ames | Iowa | 50010 | — |
| Saint Luke's Hospital | Cedar Rapids | Iowa | 52402 | — |
| Mercy Hospital | Cedar Rapids | Iowa | 52403 | — |
| Siouxland Regional Cancer Center | Sioux City | Iowa | 51101 | — |
| Harold Alfond Center for Cancer Care | Augusta | Maine | 04330 | — |
| Maine Medical Center- Scarborough Campus | Scarborough | Maine | 04074 | — |
| University of Maryland/Greenebaum Cancer Center | Baltimore | Maryland | 21201 | — |
| Sinai Hospital of Baltimore | Baltimore | Maryland | 21215 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Lahey Hospital and Medical Center | Burlington | Massachusetts | 01805 | — |
| Lowell General Hospital | Lowell | Massachusetts | 01854 | — |
| Saint Joseph Mercy Hospital | Ann Arbor | Michigan | 48106 | — |
| Beaumont Hospital-Dearborn | Dearborn | Michigan | 48124 | — |
| Mercy Health Saint Mary's | Grand Rapids | Michigan | 49503 | — |
| Spectrum Health at Butterworth Campus | Grand Rapids | Michigan | 49503 | — |
| West Michigan Cancer Center | Kalamazoo | Michigan | 49007 | — |
| Saint Mary Mercy Hospital | Livonia | Michigan | 48154 | — |
| Saint Joseph Mercy Oakland | Pontiac | Michigan | 48341 | — |
| Saint Mary's of Michigan | Saginaw | Michigan | 48601 | — |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Miller-Dwan Hospital | Duluth | Minnesota | 55805 | — |
| Unity Hospital | Fridley | Minnesota | 55432 | — |
| Abbott-Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Park Nicollet Clinic - Saint Louis Park | Saint Louis Park | Minnesota | 55416 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| United Hospital | Saint Paul | Minnesota | 55102 | — |
| Rice Memorial Hospital | Willmar | Minnesota | 56201 | — |
| Southeast Cancer Center | Cape Girardeau | Missouri | 63703 | — |
| Siteman Cancer Center at West County Hospital | Creve Coeur | Missouri | 63141 | — |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | — |
| Delbert Day Cancer Institute at PCRMC | Rolla | Missouri | 65401 | — |
| CoxHealth South Hospital | Springfield | Missouri | 65807 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Missouri Baptist Medical Center | St Louis | Missouri | 63131 | — |
| Mercy Hospital Saint Louis | St Louis | Missouri | 63141 | — |
| Nebraska Methodist Hospital | Omaha | Nebraska | 68114 | — |
| Concord Hospital | Concord | New Hampshire | 03301 | — |
| Elliot Hospital | Manchester | New Hampshire | 03103 | — |
| Virtua Memorial | Mount Holly | New Jersey | 08060 | — |
| Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital | New Brunswick | New Jersey | 08903 | — |
| Rutgers Cancer Institute of New Jersey | New Brunswick | New Jersey | 08903 | — |
| Community Medical Center | Toms River | New Jersey | 08755 | — |
| Virtua Voorhees | Voorhees Township | New Jersey | 08043 | — |
| University of New Mexico Cancer Center | Albuquerque | New Mexico | 87102 | — |
| Mary Imogene Bassett Hospital | Cooperstown | New York | 13326 | — |
| Mount Sinai Union Square | New York | New York | 10003 | — |
| Mount Sinai Hospital | New York | New York | 10029 | — |
| Weill Medical College of Cornell University | New York | New York | 10065 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| Staten Island University Hospital | Staten Island | New York | 10305 | — |
| State University of New York Upstate Medical University | Syracuse | New York | 13210 | — |
| Cancer Care of Western North Carolina | Asheville | North Carolina | 28801 | — |
| Mission Hospital-Memorial Campus | Asheville | North Carolina | 28801 | — |
| FirstHealth of the Carolinas-Moore Regional Hospital | Pinehurst | North Carolina | 28374 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Summa Akron City Hospital/Cooper Cancer Center | Akron | Ohio | 44304 | — |
| Cleveland Clinic Akron General | Akron | Ohio | 44307 | — |
| Summa Barberton Hospital | Barberton | Ohio | 44203 | — |
| Adena Regional Medical Center | Chillicothe | Ohio | 45601 | — |
| Case Western Reserve University | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Cancer Center/Fairview Hospital | Cleveland | Ohio | 44111 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio State University Comprehensive Cancer Center | Columbus | Ohio | 43210 | — |
| Grant Medical Center | Columbus | Ohio | 43215 | — |
| The Mark H Zangmeister Center | Columbus | Ohio | 43219 | — |
| Mercy Cancer Center-Elyria | Elyria | Ohio | 44035 | — |
| Cleveland Clinic Cancer Center Independence | Independence | Ohio | 44131 | — |
| North Coast Cancer Care | Sandusky | Ohio | 44870 | — |
| Cleveland Clinic Cancer Center Strongsville | Strongsville | Ohio | 44136 | — |
| Cleveland Clinic Wooster Family Health and Surgery Center | Wooster | Ohio | 44691 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Natalie Warren Bryant Cancer Center at Saint Francis | Tulsa | Oklahoma | 74136 | — |
| Clackamas Radiation Oncology Center | Clackamas | Oregon | 97015 | — |
| Legacy Mount Hood Medical Center | Gresham | Oregon | 97030 | — |
| Legacy Good Samaritan Hospital and Medical Center | Portland | Oregon | 97210 | — |
| Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Providence Saint Vincent Medical Center | Portland | Oregon | 97225 | — |
| Kaiser Permanente Northwest | Portland | Oregon | 97227 | — |
| Salem Hospital | Salem | Oregon | 97301 | — |
| Bryn Mawr Hospital | Bryn Mawr | Pennsylvania | 19010 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822 | — |
| Paoli Memorial Hospital | Paoli | Pennsylvania | 19301 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Guthrie Medical Group PC-Robert Packer Hospital | Sayre | Pennsylvania | 18840 | — |
| Lankenau Medical Center | Wynnewood | Pennsylvania | 19096 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Greenville Health System Cancer Institute-Faris | Greenville | South Carolina | 29605 | — |
| Greenville Health System Cancer Institute-Eastside | Greenville | South Carolina | 29615 | — |
| Self Regional Healthcare | Greenwood | South Carolina | 29646 | — |
| Greenville Health System Cancer Institute-Greer | Greer | South Carolina | 29650 | — |
| Gibbs Cancer Center-Pelham | Greer | South Carolina | 29651 | — |
| Greenville Health System Cancer Institute-Seneca | Seneca | South Carolina | 29672 | — |
| Spartanburg Medical Center | Spartanburg | South Carolina | 29303 | — |
| Greenville Health System Cancer Institute-Spartanburg | Spartanburg | South Carolina | 29307 | — |
| The Don and Sybil Harrington Cancer Center | Amarillo | Texas | 79106 | — |
| UT Southwestern/Simmons Cancer Center-Dallas | Dallas | Texas | 75390 | — |
| M D Anderson Cancer Center | Houston | Texas | 77030 | — |
| Covenant Medical Center-Lakeside | Lubbock | Texas | 79410 | — |
| Intermountain Medical Center | Murray | Utah | 84107 | — |
| Dixie Medical Center Regional Cancer Center | St. George | Utah | 84770 | — |
| PeaceHealth Saint John Medical Center | Longview | Washington | 98632 | — |
| PeaceHealth Southwest Medical Center | Vancouver | Washington | 98664 | — |
| Edwards Comprehensive Cancer Center | Huntington | West Virginia | 25701 | — |
| Saint Vincent Hospital Cancer Center Green Bay | Green Bay | Wisconsin | 54301 | — |
| Saint Vincent Hospital Cancer Center at Saint Mary's | Green Bay | Wisconsin | 54303 | — |
| Community Memorial Hospital | Menomonee Falls | Wisconsin | 53051 | — |
| Columbia Saint Mary's Hospital - Ozaukee | Mequon | Wisconsin | 53097 | — |
| Columbia Saint Mary's Water Tower Medical Commons | Milwaukee | Wisconsin | 53211 | — |
| Froedtert and the Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
| Cancer Center of Western Wisconsin | New Richmond | Wisconsin | 54017 | — |
| ProHealth Waukesha Memorial Hospital | Waukesha | Wisconsin | 53188 | — |
| The Alyce and Elmore Kraemer Cancer Care Center | West Bend | Wisconsin | 53095 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01822496, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 5, 2019 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01822496 live on ClinicalTrials.gov.