Chemotherapy Plus Cetuximab in Combination With VTX-2337 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Public ClinicalTrials.gov record NCT01836029. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled Study of Chemotherapy Plus Cetuximab in Combination With VTX 2337 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare the progression-free survival of patients with recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN) treated with VTX-2337 + cisplatin or carboplatin + 5-FU + cetuximab versus patients treated with cisplatin or carboplatin + 5-FU + cetuximab alone (standard-of-care; SOC). Safety and overall survival will also be evaluated.
Study identification
- NCT ID
- NCT01836029
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 195 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 14, 2013 (Actual)
- Primary completion
- Apr 13, 2016 (Actual)
- Completion
- Sep 19, 2016 (Actual)
- Last update posted
- Oct 29, 2019
2013 – 2016
United States locations
- U.S. sites
- 53
- U.S. states
- 29
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Tower Hematology Oncology Medical Group | Beverly Hills | California | 90211 | — |
| California Cancer Associates for Research and Excellence (CCARE) | Escondido | California | 92025 | — |
| University of California San Diego Moores Cancer Center | La Jolla | California | 92093 | — |
| University of California Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| University of Colorado Cancer Center | Aurora | Colorado | 80045 | — |
| VA Eastern Colorado Healthcare System | Denver | Colorado | 80220 | — |
| Helen F. Graham Cancer Center | Newark | Delaware | 19713 | — |
| MD Anderson Cancer Center | Orlando | Florida | 32806 | — |
| Northeast Georgia Cancer Care, LLC | Athens | Georgia | 30607 | — |
| Winship Cancer Institute | Atlanta | Georgia | 30322 | — |
| Tripler Army Medical Center | Honolulu | Hawaii | 96859 | — |
| Northwestern University Feinberg School of Medicine | Chicago | Illinois | 60611 | — |
| Carle Cancer Center | Urbana | Illinois | 61801 | — |
| University of Kansas Cancer Center | Westwood | Kansas | 66205 | — |
| Crescent City Research Consortium, LLC | Marrero | Louisiana | 70072 | — |
| Robert W. Veith, MD, LLC | Metairie | Louisiana | 70006-2936 | — |
| Maine Center for Cancer Medicine | Scarborough | Maine | 04074 | — |
| The Sidney Kimmel Comprehensive Cancer Center at John Hopkins | Baltimore | Maryland | 21231 | — |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20889 | — |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Providence Cancer Institute | Southfield | Michigan | 48075 | — |
| Saint Louis Cancer Care, LLP | Bridgeton | Missouri | 63044 | — |
| Barnes Jewish Hospital | St Louis | Missouri | 63110 | — |
| Nevada Cancer Research Foundation | Las Vegas | Nevada | 89106 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Oncology and Hematology Specialists, P.A. | Denville | New Jersey | 07834 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Monter Cancer Center | Lake Success | New York | 11042 | — |
| The Bellevue Hospital | New York | New York | 10016 | — |
| Mount Sinai Medical Center | New York | New York | 10029 | — |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | 27103 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267-0502 | — |
| University Hospitals of Cleveland | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Saint Charles Medical Center | Bend | Oregon | 97701 | — |
| Providence Cancer Center | Portland | Oregon | 97213 | — |
| Saint Lukes Cancer Centre | Easton | Pennsylvania | 18045 | — |
| Pennsylvania State Hershey Cancer Institute | Hershey | Pennsylvania | 17033 | — |
| University of Pittsburgh Cancer Institute | Pittsburgh | Pennsylvania | 15232 | — |
| Hollings Cancer Center | Charleston | South Carolina | 29425 | — |
| The West Clinic | Memphis | Tennessee | 38120 | — |
| University of Texas Southwestern Medical Center at Dallas | Dallas | Texas | 75390-8852 | — |
| San Antonio Military Medical Center | Fort Sam Houston | Texas | 78234 | — |
| Virginia Cancer Specialists, PD | Fairfax | Virginia | 22031 | — |
| Medical Oncology Associates, PS | Spokane | Washington | 99208 | — |
| Madigan Army Medical Center | Tacoma | Washington | 98431 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
| Aurora Advanced Healthcare, Inc. | Wauwatosa | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01836029, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 29, 2019 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01836029 live on ClinicalTrials.gov.