The Safety/Efficacy of Rifaximin With/Without Lactulose in Participants With A History of Recurrent Hepatic Encephalopathy
Public ClinicalTrials.gov record NCT01842581. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Open-Label, Active-Controlled, Trial to Evaluate the Safety and Efficacy of Rifaximin 550 mg With and Without Lactulose in Subjects With a History of Recurrent Overt Hepatic Encephalopathy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to evaluate if rifaximin alone or rifaximin plus lactulose delays the onset of hepatic encephalopathy (HE) in participants with cirrhosis who have had a previous episode of HE.
Study identification
- NCT ID
- NCT01842581
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 222 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 8, 2013 (Actual)
- Primary completion
- Dec 17, 2014 (Actual)
- Completion
- Dec 17, 2014 (Actual)
- Last update posted
- Sep 9, 2019
2013 – 2014
United States locations
- U.S. sites
- 43
- U.S. states
- 22
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner Research | Phoenix | Arizona | 85016 | — |
| Southern California Liver Centers | Coronado | California | 92118 | — |
| UCSF/Fresno - CRMC | Fresno | California | 93721 | — |
| UCSD Clinical & Translational Research Institute | La Jolla | California | 92037 | — |
| Salix Site | Long Beach | California | 90822 | — |
| Inland Empire Liver Foundation | Rialto | California | 92377 | — |
| Salix Site | Riverside | California | 92501 | — |
| Salix Site | San Diego | California | 92103 | — |
| Salix Site | San Francisco | California | 94115 | — |
| University of Colorado Denver | Aurora | Colorado | 80045 | — |
| South Denver GI | Englewood | Colorado | 80113 | — |
| University of Florida Hepatology | Gainesville | Florida | 32610-0277 | — |
| Tampa General Medical Group | Tampa | Florida | 33605 | — |
| Gastroenterology Associates | Macon | Georgia | 31201 | — |
| Salix Site | Chicago | Illinois | 60611 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| Central Iowa Hospital Corp | Des Moines | Iowa | 50309-1453 | — |
| Salix Site | Jefferson | Louisiana | 70124 | — |
| Delta Research Partners, LLC | Monroe | Louisiana | 71201 | — |
| The Center for Liver and Biliary Disease | Baltimore | Maryland | 21202-2165 | — |
| Brigham and Women's Hospital Division of Gastroenterology & Hepatology | Boston | Massachusetts | 02115 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Kansas City Research Institute | Kansas City | Missouri | 64131 | — |
| St. Louis University | St Louis | Missouri | 63104 | — |
| Univ. of Nebraska Medical Center | Omaha | Nebraska | 68198-3285 | — |
| Concorde Medical Group PLLC | New York | New York | 10016 | — |
| New York University Medical Center | New York | New York | 10016 | — |
| Salix Site | New York | New York | 10016 | — |
| Columbia University Medical Ctr. Center for Liver Disease & Transplantation | New York | New York | 10032 | — |
| University of Rochester Strong Memorial Hospital | Rochester | New York | 14642 | — |
| Asheville Gastroenterology Associates, PA | Asheville | North Carolina | 28801 | — |
| UNC School of Medicine/Division of Gastroenterology and Hepatology | Chapel Hill | North Carolina | 27599-7584 | — |
| Carolina Medical Center | Charlotte | North Carolina | 28204 | — |
| Integris Nazh Zuhdi Transplant Institute | Oklahoma City | Oklahoma | 73112 | — |
| Albert Einstien Medical Center | Philadelphia | Pennsylvania | 19141 | — |
| Research Specialists of Texas | Houston | Texas | 77030 | — |
| Amcare Research Inc | Houston | Texas | 77090 | — |
| Salix Site | Odessa | Texas | 79761 | — |
| Alamo Medical Research | San Antonio | Texas | 78215 | — |
| Methodist Hospital | San Antonio | Texas | 78229 | — |
| University of Utah Hospital | Salt Lake City | Utah | 84132 | — |
| VCU/MCV Health Systems | Richmond | Virginia | 23298 | — |
| University of Wisconsin Hospital & Clinics | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01842581, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 9, 2019 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01842581 live on ClinicalTrials.gov.