ClinicalTrials.gov record
A Study of MEK162 vs. Physician's Choice Chemotherapy in Patients With Low-grade Serous Ovarian, Fallopian Tube or Peritoneal Cancer
ClinicalTrials.gov ID: NCT01849874
Public ClinicalTrials.gov record NCT01849874. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
The MILO Study (MEK Inhibitor in Low-grade Serous Ovarian Cancer): A Multinational, Randomized, Open-label Phase 3 Study of MEK162 vs. Physician's Choice Chemotherapy in Patients With Recurrent or Persistent Low-grade Serous Carcinomas of the Ovary, Fallopian Tube or Primary Peritoneum
Study identification
- NCT ID
- NCT01849874
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Pfizer
- Industry
- Enrollment
- 341 participants
Conditions and interventions
Conditions
Interventions
- MEK162, MEK inhibitor; oral Drug
- Physician's choice chemotherapy Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 26, 2013
- Primary completion
- Jan 19, 2016
- Completion
- Aug 22, 2022
- Last update posted
- Oct 29, 2023
2013 – 2022
United States locations
- U.S. sites
- 77
- U.S. states
- 21
- U.S. cities
- 40
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arizona Cancer Center | Phoenix | Arizona | 85004 | — |
| Associated Retina Consultants, Ltd. | Phoenix | Arizona | 85020 | — |
| Oncology Research Associates, PLLC d/b/a Pinnacle Oncology Hematology | Scottsdale | Arizona | 85258 | — |
| Keck Hospital of USC | Los Angeles | California | 90033 | — |
| LAC & USC Medical Center | Los Angeles | California | 90033 | — |
| USC Healthcare Consultation Center 1 | Los Angeles | California | 90033 | — |
| USC Healthcare Consultation Center 2 | Los Angeles | California | 90033 | — |
| USC Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| USC/Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| Admin.Office/Study Supplies Mailing Address: UCLA Medicine Hematology-Oncology | Los Angeles | California | 90095 | — |
| Doris Stein Research Center Building | Los Angeles | California | 90095 | — |
| University of California Los Angeles, Hematology-Oncology Clinic | Los Angeles | California | 90095 | — |
| Gynecologic Oncology Associates | Newport Beach | California | 92663 | — |
| University of California, Irvine/UC Irvine Health | Orange | California | 92868 | — |
| UCLA Hematology/Oncology Clinic - Santa Monica | Santa Monica | California | 90404 | — |
| UCLA Hematology Oncology Clinic Santa Clarita | Valencia | California | 91355 | — |
| UCLA Hematology - Oncology Clinic - Westlake Village | Westlake Village | California | 91361 | — |
| Rocky Mountain Lions Eye Institute | Aurora | Colorado | 80045 | — |
| University of Colorado Cancer Center | Aurora | Colorado | 80045 | — |
| University of Colorado Denver, University of Colorado Cancer Center | Aurora | Colorado | 80045 | — |
| Smilow Cancer Hospital at Yale-New Haven | New Haven | Connecticut | 06510 | — |
| Eye Physicians of Central Florida | Maitland | Florida | 32751 | — |
| Florida Hospital | Orlando | Florida | 32803 | — |
| Florida Hospital Cancer Institute | Orlando | Florida | 32804 | — |
| Eye Physicians of Central | Orlando | Florida | 32835 | — |
| H. Lee Moffitt Cancer Center and Research Institute | Tampa | Florida | 33612-9497 | — |
| Florida Cancer Specialists | Wellington | Florida | 33414 | — |
| Florida Cancer Specialists | West Palm Beach | Florida | 33401 | — |
| Georgia Regents University Cancer Center | Augusta | Georgia | 30912 | — |
| University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| St. Vincent Cancer Care | Indianapolis | Indiana | 46260 | — |
| St. Vincent Gynecologic Oncology | Indianapolis | Indiana | 46260 | — |
| St. Vincent Gynecology Oncology | Indianapolis | Indiana | 46260 | — |
| St. Vincent Hospital and Health Care Center, Inc. | Indianapolis | Indiana | 46260 | — |
| Associated Vitreoretinal and Uveitis Consultants | Indianapolis | Indiana | 46290 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| University of Maryland Greenebaum Cancer Center | Baltimore | Maryland | 21201 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Ophthalmic Consultants of Boston (OCB) | Boston | Massachusetts | 02114 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Kresge Eye Institute | Detroit | Michigan | 48201 | — |
| Karmanos Cancer Institute | Farmington Hills | Michigan | 48334 | — |
| Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| Center for Advanced Medicine | St Louis | Missouri | 63110 | — |
| Center For Clinical Studies | St Louis | Missouri | 63110 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| Billings Clinic | Billings | Montana | 59101 | — |
| University of New Mexico Cancer Center | Albuquerque | New Mexico | 87106 | — |
| Eye Associates of New Mexico | Albuquerque | New Mexico | 87109 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10022 | — |
| Montefiore Medical Center - Einstein Center for Cancer Care | The Bronx | New York | 10461 | — |
| Montefiore Medical Center | The Bronx | New York | 10461 | — |
| Montefiore Medical Center - Centennial Women's Health | The Bronx | New York | 10467 | — |
| Montefiore Medical Center, Green Medical Arts Pavilion | The Bronx | New York | 10467 | — |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | — |
| Fairview Hospital Moll Pavilion Cancer Center | Cleveland | Ohio | 44111 | — |
| Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | 44195 | — |
| Cleveland Clinic-Main Campus | Cleveland | Ohio | 44195 | — |
| James Cancer Hospital & Solove Research Institute | Columbus | Ohio | 43210 | — |
| OSU Wexner Medical Center | Columbus | Ohio | 43210 | — |
| Stefanie Spielman Comprehensive Breast Cancer | Columbus | Ohio | 43212 | — |
| OSU Gynecologic Oncology at Mill Run | Hilliard | Ohio | 43026 | — |
| Hillcrest Hospital | Mayfield Heights | Ohio | 44124 | — |
| University of Cincinnati Physicians Company | West Chester | Ohio | 45219 | — |
| Dean McGee Eye Institute | Oklahoma City | Oklahoma | 73104 | — |
| Stephenson Cancer Center(clinic location) | Oklahoma City | Oklahoma | 73104 | — |
| Stephenson Cancer Center | Oklahoma City | Oklahoma | 73104 | — |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | — |
| Jeanes Hospital | Philadelphia | Pennsylvania | 19111 | — |
| Magee-Womens Hospital of UPMC | Pittsburgh | Pennsylvania | 15213 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Parkland Health and Hospital System | Dallas | Texas | 75235 | — |
| UT Southwestern Medical Center-Zale Lipshy University Hospital | Dallas | Texas | 75235 | — |
| UT Southwestern Medical Center-Clements University Hospital | Dallas | Texas | 75390 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| University of Virginia | Charlottesville | Virginia | 22903 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 149 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01849874, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 29, 2023 · Synced May 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01849874 live on ClinicalTrials.gov.