POSITIVE Stroke Clinical Trial
Public ClinicalTrials.gov record NCT01852201. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
POSITIVE: PerfusiOn Imaging Selection of Ischemic STroke PatIents for EndoVascular ThErapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Primary Endpoint: The primary objective is to show that AIS patients, ineligible for or refractory to treatment with IV-tPA, with appropriate image selection, treated with mechanical thrombectomy within 6-12 hours of symptom onset have less stroke related disability and improved good functional outcomes as compared to those treated with best MT with respect to endpoint defined as: • 90-day global disability assessed via the modified Rankin score (mRS), analyzed using raw mRS scores. Statistical details can be found in section 7.2. Secondary Endpoints: * 90-day global disability in the 6-12 hr cohort assessed via the overall distribution of mRS * Proportion of patients with good functional recovery for the 6-12 hr cohort as defined by mRS 0-2 at 90 days * Mortality at 30 and 90 days * Intracranial hemorrhage with neurological deterioration (NIHSS worsening \>4) within 24 hours of randomization * Procedure related serious adverse events (SAE's) * Arterial revascularization measured by TICI 2b or 3 following device use
Study identification
- NCT ID
- NCT01852201
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 33 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2013 (Type not available)
- Primary completion
- May 31, 2017 (Actual)
- Completion
- May 31, 2017 (Actual)
- Last update posted
- Nov 13, 2019
2013 – 2017
United States locations
- U.S. sites
- 20
- U.S. states
- 14
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| St. Joseph's Hospital and Medical Center | Phoenix | Arizona | 85013 | — |
| Cedars Sinai Medical Center | Los Angeles | California | 90048 | — |
| Swedish/Colorado Neurological Institute | Englewood | Colorado | 80113 | — |
| Baptist Health | Jacksonville | Florida | 32207 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Univesity of Massachusetts-Worcester | Worcester | Massachusetts | 01655 | — |
| Saint Luke's Hospital | Kansas City | Missouri | 64111 | — |
| Captial Health | Trenton | New Jersey | 08638 | — |
| University of Buffalo Neurosurgery | Buffalo | New York | 14203 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| Stony Brook Medical Center | Stony Brook | New York | 11764 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Ohio Health | Columbus | Ohio | 43214 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29461 | — |
| Tennessee Interventional Associates | Chattanooga | Tennessee | 37403 | — |
| Fort Sanders Regional Medical Center | Knoxville | Tennessee | 37916 | — |
| Methodist Healthcare - Memphis | Memphis | Tennessee | 38104 | — |
| Vanderbilt University | Nashville | Tennessee | 37232 | — |
| West Virginia University | Morgantown | West Virginia | 26506 | — |
| Wisconsin University | Madison | Wisconsin | 98374 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01852201, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 13, 2019 · Synced Oct 16, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01852201 live on ClinicalTrials.gov.