An Evaluation of Dupilumab in Patients With Moderate to Severe Uncontrolled Asthma
Public ClinicalTrials.gov record NCT01854047. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate Dupilumab in Patients With Moderate to Severe Uncontrolled Asthma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Primary Objective: To evaluate the efficacy of different doses and regimens of dupilumab in participants with moderate to severe uncontrolled asthma. Secondary Objective: To evaluate different doses and regimens of dupilumab in participants with moderate to severe uncontrolled asthma, with regard to: * Safety and tolerability * Dupilumab systemic exposure and anti-drug antibodies
Study identification
- NCT ID
- NCT01854047
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 776 participants
Conditions and interventions
Conditions
Interventions
- Dupilumab Drug
- placebo Drug
- ICS/LABA therapy Drug
- Salbutamol/albuterol Drug
- Levosalbutamol/levalbuterol Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2013 (Type not available)
- Primary completion
- Nov 2014 (Actual)
- Completion
- Apr 2015 (Actual)
- Last update posted
- Jun 26, 2017
2013 – 2015
United States locations
- U.S. sites
- 50
- U.S. states
- 24
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Investigational Site Number 840050 | Fullerton | California | 92835 | — |
| Investigational Site Number 840041 | Huntington Beach | California | 92647 | — |
| Investigational Site Number 840019 | Los Angeles | California | 90025 | — |
| Investigational Site Number 840029 | Los Angeles | California | 90025 | — |
| Investigational Site Number 840022 | Los Angeles | California | 90048 | — |
| Investigational Site Number 840013 | Mission Viejo | California | 92691 | — |
| Investigational Site Number 840044 | Newport Beach | California | 92663 | — |
| Investigational Site Number 840007 | Riverside | California | 92506 | — |
| Investigational Site Number 840014 | Rolling Hills Estates | California | 90274 | — |
| Investigational Site Number 840036 | San Jose | California | 95117 | — |
| Investigational Site Number 840032 | Colorado Springs | Colorado | 80907 | — |
| Investigational Site Number 840040 | Colorado Springs | Colorado | 80907 | — |
| Investigational Site Number 840043 | Denver | Colorado | 80206 | — |
| Investigational Site Number 840006 | Denver | Colorado | 80230 | — |
| Investigational Site Number 840024 | Denver | Colorado | 80230 | — |
| Investigational Site Number 840027 | Daytona Beach | Florida | 32117 | — |
| Investigational Site Number 840039 | Miami | Florida | 33135 | — |
| Investigational Site Number 840048 | Albany | Georgia | 31707 | — |
| Investigational Site Number 840026 | River Forest | Illinois | 60305 | — |
| Investigational Site Number 840053 | Evansville | Indiana | 47713 | — |
| Investigational Site Number 840017 | Louisville | Kentucky | 40223-5440 | — |
| Investigational Site Number 840030 | Owensboro | Kentucky | 42303 | — |
| Investigational Site Number 840028 | Baltimore | Maryland | 21287 | — |
| Investigational Site Number 840052 | Wheaton | Maryland | 20902 | — |
| Investigational Site Number 840045 | North Dartmouth | Massachusetts | 02747 | — |
| Investigational Site Number 840046 | Novi | Michigan | 48375 | — |
| Investigational Site Number 840051 | Novi | Michigan | 48375 | — |
| Investigational Site Number 840018 | Minneapolis | Minnesota | 55402 | — |
| Investigational Site Number 840002 | St Louis | Missouri | 63110 | — |
| Investigational Site Number 840003 | St Louis | Missouri | 63141 | — |
| Investigational Site Number 840037 | Missoula | Montana | 59804 | — |
| Investigational Site Number 840004 | Papillion | Nebraska | 27103 | — |
| Investigational Site Number 840011 | Princeton | New Jersey | 08540 | — |
| Investigational Site Number 840016 | Rochester | New York | 14618 | — |
| Investigational Site Number 840025 | Cincinnati | Ohio | 45231 | — |
| Investigational Site Number 840015 | Cincinnati | Ohio | 45236 | — |
| Investigational Site Number 840020 | Cincinnati | Ohio | 45241 | — |
| Investigational Site Number 840001 | Oklahoma City | Oklahoma | 73120 | — |
| Investigational Site Number 840031 | Lake Oswego | Oregon | 97035 | — |
| Investigational Site Number 840034 | Medford | Oregon | 97504 | — |
| Investigational Site Number 840042 | Philadelphia | Pennsylvania | 19107 | — |
| Investigational Site Number 840010 | Pittsburgh | Pennsylvania | 15213 | — |
| Investigational Site Number 840009 | Upland | Pennsylvania | 19013 | — |
| Investigational Site Number 840021 | Spartanburg | South Carolina | 29303 | — |
| Investigational Site Number 840023 | Dallas | Texas | 75231 | — |
| Investigational Site Number 840005 | El Paso | Texas | 79902 | — |
| Investigational Site Number 840008 | San Antonio | Texas | 78229 | — |
| Investigational Site Number 840035 | Richmond | Virginia | 23225 | — |
| Investigational Site Number 840054 | Everett | Washington | 98203 | — |
| Investigational Site Number 840033 | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 151 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01854047, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 26, 2017 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01854047 live on ClinicalTrials.gov.