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Completed Phase 2 Interventional Results available

Proof-Of-Concept Investigation With a Neurosteroid Analog (Ganaxolone) as a Smoking Cessation Candidate

ClinicalTrials.gov ID: NCT01857531

Public ClinicalTrials.gov record NCT01857531. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 12:08 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this research study is to evaluate whether the investigational drug ganaxolone can help smokers quit smoking. Ganaxolone is a drug that has been investigated (in other research studies) for the treatment of seizures and migraines. This drug is considered investigational in the US.

Study identification

NCT ID
NCT01857531
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Jed E. Rose
Other
Enrollment
36 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 31, 2013
Primary completion
Jun 30, 2013
Completion
Jan 31, 2014
Last update posted
Sep 7, 2014

2013 – 2014

United States locations

U.S. sites
4
U.S. states
1
U.S. cities
4
Facility City State ZIP Site status
Duke Center for Smoking Cessation Charlotte North Carolina 28210
Duke Center for Smoking Cessation Durham North Carolina 27705
Duke Center for Smoking Cessation Raleigh North Carolina 27609
Duke Center for Smoking Cessation Winston-Salem North Carolina 27103

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01857531, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 7, 2014 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01857531 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →