A Study of Lebrikizumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)
Public ClinicalTrials.gov record NCT01872689. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Randomized, Double-Blind, Placebo-Controlled, Study to Assess the Efficacy and Safety of Lebrikizumab in Patients With Idiopathic Pulmonary Fibrosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This randomized, multicenter, double-blind, placebo-controlled, parallel-group study will evaluate the efficacy and safety of lebrikizumab as monotherapy in the absence of background IPF therapy and as combination therapy with pirfenidone background therapy in participants with IPF. Participants will be randomized to receive either lebrikizumab or placebo subcutaneously every 4 weeks.
Study identification
- NCT ID
- NCT01872689
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 505 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 13, 2013 (Actual)
- Primary completion
- Jul 28, 2017 (Actual)
- Completion
- Nov 6, 2017 (Actual)
- Last update posted
- Aug 24, 2018
2013 – 2017
United States locations
- U.S. sites
- 54
- U.S. states
- 31
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University Alabama At Birmingham | Birmingham | Alabama | 35294 | — |
| Mayo Clinic- Scottsdale | Scottsdale | Arizona | 85259 | — |
| Southern Arizona Veterans Administration Healthcare Systems | Tucson | Arizona | 85723 | — |
| University of Arizona | Tucson | Arizona | 85724-5030 | — |
| UCSD Medical Center | La Jolla | California | 92093 | — |
| University of California, San Francisco | San Francisco | California | 94116 | — |
| National Jewish Health | Denver | Colorado | 80206 | — |
| Rocky Mountain Center For Clinical Research | Wheat Ridge | Colorado | 80033 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 06520 | — |
| Research Alliance Inc | Clearwater | Florida | 33756 | — |
| Mayo Clinic-Jacksonville | Jacksonville | Florida | 32224 | — |
| University Miami | Miami | Florida | 33136 | — |
| Central Florida Pulmonary Group, PA | Orlando | Florida | 32803 | — |
| USF Tampa General Hospital | Tampa | Florida | 33606 | — |
| Cleveland Clinic Florida | Weston | Florida | 33331 | — |
| Piedmont Healthcare Pulmonary and Critical Care Research | Austell | Georgia | 30106 | — |
| Southeastern Lung Care | Decatur | Georgia | 30033 | — |
| University of Chicago; Pulmonary and Critical Care | Chicago | Illinois | 60637 | — |
| Loyola University Med Center | Maywood | Illinois | 60153 | — |
| Univ of Iowa Hosp & Clinics; Pulmonary | Iowa City | Iowa | 52242 | — |
| Uni of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Via Christi Hospital Inc. DBA Via Christi Research; Research Dept. | Wichita | Kansas | 67208 | — |
| Maine Medical Center -Division of Pulmomary and Critical Care Medicine | Portland | Maine | 04106 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Johns Hopkins Bayview Medical Center - Johns Hopkins Asthma & Allergy Center | Baltimore | Maryland | 21224 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| University of Minnesota Hospital & Clinic | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic Rochester | Rochester | Minnesota | 55902 | — |
| Cardiopulmonary Associates LLC Cardiopulmonary Research | Chesterfield | Missouri | 63017 | — |
| University of Nebraska | Omaha | Nebraska | 68198-5300 | — |
| Lovelace Scientific Resources, Inc. | Albuquerque | New Mexico | 87108 | — |
| Weill Medical College of Cornell University | New York | New York | 10021-5663 | — |
| Mt Sinai School Medical Pulmo And Critical Care Med | New York | New York | 10029 | — |
| Highland Hospital-University of Rochester Medical Center | Rochester | New York | 14620 | — |
| University of Cincinnati | Cincinnati | Ohio | 45203-0542 | — |
| Case Western Research University; University Hospitals Case Medical Center | Cleveland | Ohio | 44106-5067 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Oklahoma University Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| The Oregon Clinic. | Portland | Oregon | 97220 | — |
| Penn State University College Medical Allergy And Care Med | Hershey | Pennsylvania | 17033 | — |
| Temple Lung Center, Temple Universtiy-Of the Commomwealth System of Higher Education | Philadelphia | Pennsylvania | 19140 | — |
| University of Pittsburgh Med Cen; Dorothy P And Richard P Simmons Cen For Interstitial Lung Disease | Pittsburgh | Pennsylvania | 15213 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Baylor College Med | Houston | Texas | 77030 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Audie Murphy Va Hospital | San Antonio | Texas | 78229 | — |
| University of Utah Health Sciences Center, Lung Health Research Center | Salt Lake City | Utah | 84108 | — |
| University Vermont College Medicine Fletcher Allen Health Care | Colchester | Vermont | 05446 | — |
| Inova Transplant Center Fairfax Hospital | Falls Church | Virginia | 22042 | — |
| Pulmonary Consultants | Tacoma | Washington | 98405 | — |
| University Wisconsin Hospitals and Clinics | Madison | Wisconsin | 53792 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 58 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01872689, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 24, 2018 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01872689 live on ClinicalTrials.gov.