A Phase 3, International, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy and Safety Trial of Linaclotide Administered Orally for 12 Weeks to Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
Public ClinicalTrials.gov record NCT01880424. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Study identification
- NCT ID
- NCT01880424
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- AstraZeneca
- Industry
- Enrollment
- 1,722 participants
Conditions and interventions
Interventions
- Placebo Drug
- Linaclotide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 30, 2013
- Primary completion
- Apr 30, 2015
- Completion
- Apr 30, 2015
- Last update posted
- Sep 26, 2016
2013 – 2015
United States locations
- U.S. sites
- 52
- U.S. states
- 21
- U.S. cities
- 52
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Huntsville | Alabama | — | — |
| Research Site | North Little Rock | Arkansas | — | — |
| Research Site | Phoenix | Arkansas | — | — |
| Research Site | Artesia | California | — | — |
| Research Site | Chula Vista | California | — | — |
| Research Site | Encino | California | — | — |
| Research Site | North Hollywood | California | — | — |
| Research Site | Orange | California | — | — |
| Research Site | Riverside | California | — | — |
| Research Site | San Diego | California | — | — |
| Research Site | Boynton Beach | Florida | — | — |
| Research Site | Brandon | Florida | — | — |
| Research Site | Brooksville | Florida | — | — |
| Research Site | Doral | Florida | — | — |
| Research Site | Gainesville | Florida | — | — |
| Research Site | Hialeah | Florida | — | — |
| Research Site | Kissimmee | Florida | — | — |
| Research Site | Lauderdale Lakes | Florida | — | — |
| Research Site | Miami | Florida | — | — |
| Research Site | Miami Lakes | Florida | — | — |
| Research Site | Addison | Illinois | — | — |
| Research Site | Evansville | Indiana | — | — |
| Research Site | Crowley | Louisiana | — | — |
| Research Site | Monroe | Louisiana | — | — |
| Research Site | Shreveport | Louisiana | — | — |
| Research Site | Boston | Massachusetts | — | — |
| Research Site | Chesterfield | Michigan | — | — |
| Research Site | Wyoming | Michigan | — | — |
| Research Site | St Louis | Missouri | — | — |
| Research Site | Billings | Montana | — | — |
| Research Site | Las Vegas | Nevada | — | — |
| Research Site | Brooklyn | New York | — | — |
| Research Site | Great Neck | New York | — | — |
| Research Site | New York | New York | — | — |
| Research Site | Raleigh | North Carolina | — | — |
| Research Site | Salisbury | North Carolina | — | — |
| Research Site | Winston-Salem | North Carolina | — | — |
| Research Site | Cincinnati | Ohio | — | — |
| Research Site | Dayton | Ohio | — | — |
| Research Site | Franklin | Ohio | — | — |
| Research Site | Mentor | Ohio | — | — |
| Research Site | Greer | South Carolina | — | — |
| Research Site | Chattanooga | Tennessee | — | — |
| Research Site | Kingsport | Tennessee | — | — |
| Research Site | Knoxville | Tennessee | — | — |
| Research Site | Smyrna | Tennessee | — | — |
| Research Site | Houston | Texas | — | — |
| Research Site | San Antonio | Texas | — | — |
| Research Site | Webster | Texas | — | — |
| Research Site | Ogden | Utah | — | — |
| Research Site | Lynchburg | Virginia | — | — |
| Research Site | Morgantown | West Virginia | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 30 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01880424, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 26, 2016 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01880424 live on ClinicalTrials.gov.