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Completed Phase 2 Interventional Results available

Phase 2 Study to Evaluate LUM001 in Combination With Ursodeoxycholic Acid in Patients With Primary Biliary Cirrhosis

ClinicalTrials.gov ID: NCT01904058

Public ClinicalTrials.gov record NCT01904058. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 4, 2026, 6:18 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Randomized, Double-blind, Placebo-controlled Study to Evaluate LUM001, an Apical Sodium-dependent Bile Acid Transporter Inhibitor (ASBTi) in Combination With Ursodeoxycholic Acid (UDCA) in Patients With Primary Biliary Cirrhosis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The study is a randomized, double-blind, placebo-controlled, multicenter study. It is a 13-week Phase 2 study in adults with primary biliary cirrhosis designed to compare the effect of daily dosing with UDCA in combination with LUM001 or placebo.

Study identification

NCT ID
NCT01904058
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Mirum Pharmaceuticals, Inc.
Industry
Enrollment
66 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 80 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2013
Primary completion
Mar 31, 2015
Completion
Mar 31, 2015
Last update posted
Mar 26, 2019

2013 – 2015

United States locations

U.S. sites
17
U.S. states
13
U.S. cities
17
Facility City State ZIP Site status
Scripps Clinic La Jolla California 92037
University of California at Davis Sacramento California 95817
University of Miami Miami Florida 33136
University of Chicago Medical Center Chicago Illinois 60637
Indiana University Indianapolis Indiana 46202
University of Louisville Louisville Kentucky 40202
Henry Ford Health System Detroit Michigan 48202
Mayo Clinic Rochester Minnesota 55905
Minnesota Gastroenterology Saint Paul Minnesota 55114
St. Louis University St Louis Missouri 63104
Weill Cornell Medical College New York New York 10021
University of Texas Southwestern Medical Center Dallas Texas 75390
Advanced Liver Therapies at St. Lukes Episcopal Hospital Houston Texas 77030
University of Utah Health Science Center Salt Lake City Utah 84132
Liver Institute of Virginia Newport News Virginia 23602
Hunter Holmes McGuire VA Medical Center Richmond Virginia 23249
University of Washington Harborview Medical Center Seattle Washington 98104

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01904058, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 26, 2019 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01904058 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →