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Terminated Phase 2Phase 3 Interventional Results available

Nintedanib (BIBF 1120) in Mesothelioma

ClinicalTrials.gov ID: NCT01907100

Public ClinicalTrials.gov record NCT01907100. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 7:06 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

LUME-Meso: Double Blind, Randomised, Multicentre, Phase II/III Study of Nintedanib in Combination With Pemetrexed / Cisplatin Followed by Continuing Nintedanib Monotherapy Versus Placebo in Combination With Pemetrexed / Cisplatin Followed by Continuing Placebo Monotherapy for the Treatment of Patients With Unresectable Malignant Pleural Mesothelioma

Study identification

NCT ID
NCT01907100
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Boehringer Ingelheim
Industry
Enrollment
545 participants

Conditions and interventions

Conditions

Interventions

  • Nintedanib Drug
  • Pemetrexed Drug
  • Cisplatin Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 18, 2013
Primary completion
Mar 15, 2018
Completion
Aug 30, 2018
Last update posted
Mar 17, 2019

2013 – 2018

United States locations

U.S. sites
10
U.S. states
8
U.S. cities
10
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35249
University of California San Francisco San Francisco California 94115
Rocky Mountain Cancer Centers Littleton Colorado 80120-4413
Comprehensive Cancer Centers of Nevada Henderson Nevada 89052
University of Pittsburgh Medical Center Pittsburgh Pennsylvania 15232
Greenville Health System Greenville South Carolina 29615
The University of Texas MD Anderson Cancer Center Houston Texas 77030
Texas Oncology - McAllen McAllen Texas 78503
Texas Oncology-San Antonio Northeast San Antonio Texas 78217
Cancer Care Northwest Centers, PS Spokane Valley Washington 99216

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 113 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01907100, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 17, 2019 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01907100 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →