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Completed Phase 3 Interventional Results available

Study of Cabozantinib (XL184) vs Placebo in Subjects With Hepatocellular Carcinoma Who Have Received Prior Sorafenib

ClinicalTrials.gov ID: NCT01908426

Public ClinicalTrials.gov record NCT01908426. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 27, 2026, 2:46 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Randomized, Double-blind, Controlled Study of Cabozantinib (XL184) vs Placebo in Subjects With Hepatocellular Carcinoma Who Have Received Prior Sorafenib

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the effect of Cabozantinib (XL184) compared with placebo on overall survival in subjects with advanced hepatocellular carcinoma who have received prior sorafenib.

Study identification

NCT ID
NCT01908426
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Exelixis
Industry
Enrollment
707 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 25, 2013
Primary completion
Oct 15, 2017
Completion
Jan 11, 2021
Last update posted
May 5, 2021

2013 – 2021

United States locations

U.S. sites
22
U.S. states
13
U.S. cities
20
Facility City State ZIP Site status
Not listed Corona California 92879 —
Not listed Los Angeles California 90033 —
Not listed San Diego California 92123 —
Not listed San Francisco California 94115 —
Not listed Gainesville Florida 32610 —
Not listed Atlanta Georgia 30318 —
Not listed Honolulu Hawaii 96815 —
Not listed Chicago Illinois 60637 —
Not listed Burlington Massachusetts 01805 —
Not listed Rochester Minnesota 55905 —
Not listed Kansas City Missouri 64128 —
Not listed St Louis Missouri 63110 —
Not listed Las Vegas Nevada 89109 —
Not listed East Orange New Jersey 07018 —
Not listed New York New York 10032 —
Not listed New York New York 10065 —
Not listed Valhalla New York 10595 —
Not listed Dallas Texas 75246 —
Not listed San Antonio Texas 78215 —
Not listed Seattle Washington 98104 —
Not listed Seattle Washington 98109 —
Not listed Spokane Washington 99208 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 82 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01908426, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 5, 2021 · Synced Sep 27, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01908426 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →