Beraprost-314d Added-on to Tyvaso® (BEAT)
Public ClinicalTrials.gov record NCT01908699. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Double-blind, Randomized, Placebo-controlled, Phase 3 Study to Assess the Efficacy and Safety of Oral BPS-314d-MR added-on to Treprostinil, Inhaled (Tyvaso®) in Subjects With Pulmonary Arterial Hypertension
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multicenter, double-blind, randomized, placebo-controlled Phase 3 study, to assess the efficacy and safety of BPS-314d-MR when added-on to inhaled treprostinil (Tyvaso®)in patients with pulmonary arterial hypertension. Patients new to Tyvaso, will enter a run-in period on inhaled treprostinil until 90 days of experience is achieved to ensure drug tolerability before enrolling in the study. Treatment groups consist of one active and one placebo group. Subjects will be randomly allocated in a 1:1 ratio to one of the two treatment groups.
Study identification
- NCT ID
- NCT01908699
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 273 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2013 (Actual)
- Primary completion
- Feb 19, 2019 (Actual)
- Completion
- Feb 19, 2019 (Actual)
- Last update posted
- Aug 3, 2020
2013 – 2019
United States locations
- U.S. sites
- 69
- U.S. states
- 27
- U.S. cities
- 58
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35249 | — |
| Cedars-Sinai Medical Center Heart Institute | Beverly Hills | California | 90211 | — |
| Allianz Research Institute Inc. | Fountain Valley | California | 92708 | — |
| University of California San Francisco - Fresno | Fresno | California | 93720 | — |
| University of California - San Diego | La Jolla | California | 92093 | — |
| University of California Los Angeles | Los Angeles | California | 90024 | — |
| Keck Medical Center of USC | Los Angeles | California | 90033 | — |
| Veterans Affairs Greater Los Angeles Healthcare System | Los Angeles | California | 90073 | — |
| Center for Advanced Pulmonary Medicine | Rancho Mirage | California | 92270 | — |
| University of California - San Francisco | San Francisco | California | 94143 | — |
| Cottage Pulmonary Hypertension Center | Santa Barbara | California | 93105 | — |
| Stanford University | Stanford | California | 94305 | — |
| Harbor-UCLA Medical Center | Torrance | California | 90502 | — |
| University of Colorado Denver | Aurora | Colorado | 80045 | — |
| Aurora Denver Cardiology Associates | Denver | Colorado | 80218 | — |
| South Denver Cardiology Associates P.C. | Littleton | Colorado | 80120 | — |
| Yale School of Medicine | New Haven | Connecticut | 06510 | — |
| Bay Area Cardiology Associates, P.A. | Brandon | Florida | 33511 | — |
| Florida Lung, Asthma, and Sleep Institute | Celebration | Florida | 34747 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| University of Florida College of Medicine | Jacksonville | Florida | 32209 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| Florida Hospital | Orlando | Florida | 32804 | — |
| Orlando Health Heart Institute | Orlando | Florida | 32806 | — |
| South Miami Heart Specialists | South Miami | Florida | 33143 | — |
| Cleveland Clinic Florida | Weston | Florida | 33331 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Pulmonary & Critical Care of Atlanta | Atlanta | Georgia | 30342 | — |
| Georgia Clinical Research | Austell | Georgia | 30106 | — |
| Gwinnett Biomedical Research | Lawrenceville | Georgia | 30046 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Chicago Medicine | Chicago | Illinois | 60637 | — |
| Advocate Health and Hospitals Corporation | Oakbrook Terrace | Illinois | 60181 | — |
| Indiana University - Health Physicians | Carmel | Indiana | 46032 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| Kentuckiana Pulmonary Associates | Louisville | Kentucky | 40202 | — |
| University of Louisville Department of Medicine | Louisville | Kentucky | 40202 | — |
| John Ochsner Heart & Vascular Institute | New Orleans | Louisiana | 70121 | — |
| Maine Medical Center | Portland | Maine | 04102 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Johns Hopkins University School of Medicine | Baltimore | Maryland | 21205 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Beaumont Health Systems | Troy | Michigan | 48085 | — |
| Rutgers University Hospital | Newark | New Jersey | 07103 | — |
| Albany Medical College | Albany | New York | 12206 | — |
| Winthrop University Hospital | Mineola | New York | 11501 | — |
| Beth Israel Medical Center | New York | New York | 10003 | — |
| Mount Sinai Medical Center | New York | New York | 10029 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Pulmonary Health Physicians, PC | Syracuse | New York | 13210 | — |
| University of North Carolina, Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| University of Cincinnati | Cincinnati | Ohio | 45627 | — |
| University Hospitals Case Medical Center | Cleveland | Ohio | 44106 | — |
| Ohio State University | Columbus | Ohio | 43221 | — |
| University of Toledo Medical Center | Toledo | Ohio | 43614 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| UPMC Presbyterian Hospital | Pittsburgh | Pennsylvania | 15213 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| Anderson Pharmaceutical Research | Anderson | South Carolina | 29621 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Methodist Healthcare Clinical Trials Office | San Antonio | Texas | 78229 | — |
| Scott & White Memorial Hospital | Temple | Texas | 76508 | — |
| Sentara Norfolk General Hospital | Norfolk | Virginia | 23507 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01908699, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 3, 2020 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01908699 live on ClinicalTrials.gov.