Add-On Study of MSI-195 (S-Adenosyl-L-Methionine, SAMe) for Patients With Major Depressive Disorder (MDD)
Public ClinicalTrials.gov record NCT01912196. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-Blind, Placebo-Controlled, Randomized Add-On Study of MSI-195 (Methylation Sciences Inc. S-Adenosyl-L-Methionine, SAMe) For Patients With Major Depressive Disorder(MDD) Who Have Had An Inadequate Response to Current Antidepressant Therapy
Study identification
- NCT ID
- NCT01912196
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- MSI Methylation Sciences, Inc.
- Industry
- Enrollment
- 376 participants
Conditions and interventions
Conditions
Interventions
- MSI-195 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 21 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 30, 2013
- Primary completion
- Aug 31, 2015
- Completion
- Aug 31, 2015
- Last update posted
- Mar 17, 2016
2013 – 2015
United States locations
- U.S. sites
- 35
- U.S. states
- 17
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| MSI Investigational Site | Birmingham | Alabama | 35216 | — |
| MSI Investigational Site | Encino | California | 91316 | — |
| MSI Investigational Site | Escondido | California | 92025 | — |
| MSI Investigational Site | Garden Grove | California | 92845 | — |
| MSI Investigational Site | Los Alamitos | California | 90720 | — |
| MSI Investigational Site | Los Angeles | California | 90024 | — |
| MSI Investigational Site | National City | California | 91950 | — |
| MSI Investigational Site | Newport Beach | California | 92660 | — |
| MSI Investigational Site | Oakland | California | 94612 | — |
| MSI Investigational Site | Oceanside | California | 92056 | — |
| MSI Investigational Site | Torrance | California | 90502 | — |
| MSI Investigational Site | Jacksonville | Florida | 32256 | — |
| MSI INvestigational Site | Kissimmee | Florida | 34741 | — |
| MSI Investigational Site | Lauderhill | Florida | 33319 | — |
| MSI Investigational Site | Orlando | Florida | 32806 | — |
| MSI Investigational Site | Atlanta | Georgia | 30328 | — |
| MSI Investigational Site | Hoffman Estates | Illinois | 60169 | — |
| MSI Investigational Site | Towson | Maryland | 21285 | — |
| MSI Investigational Site | Flowood | Mississippi | 39232 | — |
| MSI Investigational Site | Las Vegas | Nevada | 89102 | — |
| MSI Investigational Site | Marlton | New Jersey | 08053 | — |
| MSI Investigational Site | Albuquerque | New Mexico | 87109 | — |
| MSI Investigational Site | New York | New York | 10128 | — |
| MSI Investigational Site | Rochester | New York | 14618 | — |
| MSI Investigational Site | Canton | Ohio | 44718 | — |
| MSI Investigational Site | Dayton | Ohio | 45417 | — |
| MSI Investigational Site | Portland | Oregon | 97210 | — |
| MSI Investigational Site | Memphis | Tennessee | 38119 | — |
| MSI Investigational Site | Austin | Texas | 78731 | — |
| MSI Investigational Site | Austin | Texas | 78754 | — |
| MSI Investigational Site | Dallas | Texas | 75231 | — |
| MSI Investigational Site | Houston | Texas | 77008 | — |
| MSI Investigational Site | Houston | Texas | 77098 | — |
| MSI Investigational Site | Murray | Utah | 84123 | — |
| MSI Investigational Site | Bellevue | Washington | 98007 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01912196, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 17, 2016 · Synced Jun 26, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01912196 live on ClinicalTrials.gov.