Add-On Study of MSI-195 (S-Adenosyl-L-Methionine, SAMe) for Patients With Major Depressive Disorder (MDD)
Public ClinicalTrials.gov record NCT01912196. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-Blind, Placebo-Controlled, Randomized Add-On Study of MSI-195 (Methylation Sciences Inc. S-Adenosyl-L-Methionine, SAMe) For Patients With Major Depressive Disorder(MDD) Who Have Had An Inadequate Response to Current Antidepressant Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the efficacy and safety of 800 mg MSI-195 in reducing symptoms of depression in Major Depressive Disorder (MDD)patients with inadequate response to current antidepressant therapy.
Study identification
- NCT ID
- NCT01912196
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 376 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 21 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2013 (Type not available)
- Primary completion
- Sep 2015 (Actual)
- Completion
- Sep 2015 (Actual)
- Last update posted
- Mar 18, 2016
2013 – 2015
United States locations
- U.S. sites
- 35
- U.S. states
- 17
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| MSI Investigational Site | Birmingham | Alabama | 35216 | — |
| MSI Investigational Site | Encino | California | 91316 | — |
| MSI Investigational Site | Escondido | California | 92025 | — |
| MSI Investigational Site | Garden Grove | California | 92845 | — |
| MSI Investigational Site | Los Alamitos | California | 90720 | — |
| MSI Investigational Site | Los Angeles | California | 90024 | — |
| MSI Investigational Site | National City | California | 91950 | — |
| MSI Investigational Site | Newport Beach | California | 92660 | — |
| MSI Investigational Site | Oakland | California | 94612 | — |
| MSI Investigational Site | Oceanside | California | 92056 | — |
| MSI Investigational Site | Torrance | California | 90502 | — |
| MSI Investigational Site | Jacksonville | Florida | 32256 | — |
| MSI INvestigational Site | Kissimmee | Florida | 34741 | — |
| MSI Investigational Site | Lauderhill | Florida | 33319 | — |
| MSI Investigational Site | Orlando | Florida | 32806 | — |
| MSI Investigational Site | Atlanta | Georgia | 30328 | — |
| MSI Investigational Site | Hoffman Estates | Illinois | 60169 | — |
| MSI Investigational Site | Towson | Maryland | 21285 | — |
| MSI Investigational Site | Flowood | Mississippi | 39232 | — |
| MSI Investigational Site | Las Vegas | Nevada | 89102 | — |
| MSI Investigational Site | Marlton | New Jersey | 08053 | — |
| MSI Investigational Site | Albuquerque | New Mexico | 87109 | — |
| MSI Investigational Site | New York | New York | 10128 | — |
| MSI Investigational Site | Rochester | New York | 14618 | — |
| MSI Investigational Site | Canton | Ohio | 44718 | — |
| MSI Investigational Site | Dayton | Ohio | 45417 | — |
| MSI Investigational Site | Portland | Oregon | 97210 | — |
| MSI Investigational Site | Memphis | Tennessee | 38119 | — |
| MSI Investigational Site | Austin | Texas | 78731 | — |
| MSI Investigational Site | Austin | Texas | 78754 | — |
| MSI Investigational Site | Dallas | Texas | 75231 | — |
| MSI Investigational Site | Houston | Texas | 77008 | — |
| MSI Investigational Site | Houston | Texas | 77098 | — |
| MSI Investigational Site | Murray | Utah | 84123 | — |
| MSI Investigational Site | Bellevue | Washington | 98007 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01912196, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 18, 2016 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01912196 live on ClinicalTrials.gov.