A Study to Evaluate the Clinical Efficacy and Safety of Subcutaneously Administered C1-esterase Inhibitor in the Prevention of Hereditary Angioedema
Public ClinicalTrials.gov record NCT01912456. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-blind, Randomized, Placebo-controlled, Cross-over Study to Evaluate the Clinical Efficacy and Safety of Subcutaneous Administration of Human Plasma-derived C1-esterase Inhibitor in the Prophylactic Treatment of Hereditary Angioedema
Study identification
- NCT ID
- NCT01912456
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- CSL Behring
- Industry
- Enrollment
- 90 participants
Conditions and interventions
Conditions
Interventions
- Low-volume C1-esterase inhibitor Biological
- Higher-volume C1-esterase inhibitor Biological
- Low-volume placebo Biological
- Higher-volume placebo Biological
Biological
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 31, 2013
- Primary completion
- Sep 30, 2015
- Completion
- Sep 30, 2015
- Last update posted
- Jan 28, 2021
2014 – 2015
United States locations
- U.S. sites
- 19
- U.S. states
- 13
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Study Site | Birmingham | Alabama | 35209 | — |
| Study Site | Scottsdale | Arizona | 85251 | — |
| Study Site | Bell Gardens | California | 90201 | — |
| Study Site | La Jolla | California | 92093 | — |
| Study Site | Orange | California | 92868 | — |
| Study Site | Walnut Creek | California | 94598 | — |
| Study Site | Colorado Springs | Colorado | 80907 | — |
| Study Site | Chevy Chase | Maryland | 20815 | — |
| Study Site | Boston | Massachusetts | 02114 | — |
| Study Site | Cincinnati | Ohio | 45267-0563 | — |
| Study Site | Columbus | Ohio | 43235 | — |
| Study Site | Toledo | Ohio | 43617 | — |
| Study Site | Tulsa | Oklahoma | 74136 | — |
| Study Site | Lake Oswego | Oregon | 97035 | — |
| Study Site | Hershey | Pennsylvania | 17033 | — |
| Study Site | Dallas | Texas | 75231 | — |
| Study Site | Richmond | Virginia | 23298 | — |
| Study Site | Virginia Beach | Virginia | 23452 | — |
| Study Site | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01912456, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 28, 2021 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01912456 live on ClinicalTrials.gov.