Efficacy and Safety Study of Benralizumab in Adults and Adolescents Inadequately Controlled on Inhaled Corticosteroid Plus Long-acting β2 Agonist
Public ClinicalTrials.gov record NCT01914757. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicentre, Randomized, Double-blind, Parallel Group, Placebocontrolled, Phase 3 Study to Evaluate the Efficacy and Safety of Benralizumab in Asthmatic Adults and Adolescents Inadequately Controlled on Inhaled Corticosteroid Plus Long-acting β2 Agonist (CALIMA)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether Benralizumab reduces the exacerbation rate in patients with a history of asthma exacerbations and uncontrolled asthma receiving ICS-LABA with or without oral corticosteroids and additional asthma controllers.
Study identification
- NCT ID
- NCT01914757
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 2,508 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 2013 (Type not available)
- Primary completion
- Mar 2016 (Actual)
- Completion
- Mar 2016 (Actual)
- Last update posted
- Jan 25, 2017
2013 – 2016
United States locations
- U.S. sites
- 81
- U.S. states
- 30
- U.S. cities
- 81
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Andalusia | Alabama | — | — |
| Research Site | Birmingham | Alabama | — | — |
| Research Site | Flagstaff | Arizona | — | — |
| Research Site | Glendale | Arizona | — | — |
| Research Site | Phoenix | Arizona | — | — |
| Research Site | Tucson | Arizona | — | — |
| Research Site | Alhambra | California | — | — |
| Research Site | Anaheim | California | — | — |
| Research Site | Beverly Hills | California | — | — |
| Research Site | Garden Grove | California | — | — |
| Research Site | Lakewood | California | — | — |
| Research Site | North Hollywood | California | — | — |
| Research Site | Northridge | California | — | — |
| Research Site | Palmdale | California | — | — |
| Research Site | Rancho Mirage | California | — | — |
| Research Site | Redondo Beach | California | — | — |
| Research Site | Rolling Hills Estate | California | — | — |
| Research Site | Sacramento | California | — | — |
| Research Site | Stockton | California | — | — |
| Research Site | Thousand Oaks | California | — | — |
| Research Site | Upland | California | — | — |
| Research Site | Ventura | California | — | — |
| Research Site | Walnut Creek | California | — | — |
| Research Site | Westminster | California | — | — |
| Research Site | Woodland | California | — | — |
| Research Site | Centennial | Colorado | — | — |
| Research Site | Colorado Springs | Colorado | — | — |
| Research Site | Wheat Ridge | Colorado | — | — |
| Research Site | Celebration | Florida | — | — |
| Research Site | Fort Lauderdale | Florida | — | — |
| Research Site | Hialeah | Florida | — | — |
| Research Site | Homestead | Florida | — | — |
| Research Site | Jacksonville | Florida | — | — |
| Research Site | Lehigh Acres | Florida | — | — |
| Research Site | Miami | Florida | — | — |
| Research Site | Ocala | Florida | — | — |
| Research Site | Orlando | Florida | — | — |
| Research Site | Ormond Beach | Florida | — | — |
| Research Site | Virginia Gardens | Florida | — | — |
| Research Site | Gainesville | Georgia | — | — |
| Research Site | Smyrna | Georgia | — | — |
| Research Site | Eagle | Idaho | — | — |
| Research Site | Shiloh | Illinois | — | — |
| Research Site | Lenexa | Kansas | — | — |
| Research Site | Fort Mitchell | Kentucky | — | — |
| Research Site | Covington | Louisiana | — | — |
| Research Site | Bangor | Maine | — | — |
| Research Site | Farmington Hills | Michigan | — | — |
| Research Site | Flint | Michigan | — | — |
| Research Site | Traverse City | Michigan | — | — |
| Research Site | Minneapolis | Minnesota | — | — |
| Research Site | St Louis | Missouri | — | — |
| Research Site | Las Vagas | Nevada | — | — |
| Research Site | Union | New Jersey | — | — |
| Research Site | The Bronx | New York | — | — |
| Research Site | Durham | North Carolina | — | — |
| Research Site | Wilmington | North Carolina | — | — |
| Research Site | Cincinnati | Ohio | — | — |
| Research Site | Columbus | Ohio | — | — |
| Research Site | Dayton | Ohio | — | — |
| Research Site | Middleburg Heights | Ohio | — | — |
| Research Site | Oklahoma City | Oklahoma | — | — |
| Research Site | Corvallis | Oregon | — | — |
| Research Site | Portland | Oregon | — | — |
| Research Site | Jefferson Hills | Pennsylvania | — | — |
| Research Site | Pittsburgh | Pennsylvania | — | — |
| Research Site | Old Point Station | South Carolina | — | — |
| Research Site | Rapid City | South Dakota | — | — |
| Research Site | Knoxville | Tennessee | — | — |
| Research Site | Arlington | Texas | — | — |
| Research Site | Austin | Texas | — | — |
| Research Site | Boerne | Texas | — | — |
| Research Site | Dallas | Texas | — | — |
| Research Site | Houston | Texas | — | — |
| Research Site | San Antonio | Texas | — | — |
| Research Site | Midvale | Utah | — | — |
| Research Site | Murray | Utah | — | — |
| Research Site | Fairfax | Virginia | — | — |
| Research Site | Falls Church | Virginia | — | — |
| Research Site | Madison | Wisconsin | — | — |
| Research Site | Milwaukee | Wisconsin | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 133 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01914757, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 25, 2017 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01914757 live on ClinicalTrials.gov.