ClinicalTrials.gov record
Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients With Preserved Ejection Fraction
ClinicalTrials.gov ID: NCT01920711
Public ClinicalTrials.gov record NCT01920711. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Double-blind, Parallel Group, Active-controlled Study to Evaluate the Efficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients (NYHA Class II-IV) With Preserved Ejection Fraction (PARAGON-HF)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study was to evaluate the effect of LCZ696 compared to valsartan in the reduction of cardiovascular death and heart failure(HF) hospitalizations in patients with HF with preserved ejection fraction.
Study identification
- NCT ID
- NCT01920711
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 4,822 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 18, 2014 (Actual)
- Primary completion
- Jun 7, 2019 (Actual)
- Completion
- Jun 7, 2019 (Actual)
- Last update posted
- Sep 29, 2020
2014 – 2019
United States locations
- U.S. sites
- 110
- U.S. states
- 38
- U.S. cities
- 95
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Novartis Investigative Site | Huntsville | Alabama | 35801 | — |
| Novartis Investigative Site | Mobile | Alabama | 36608 | — |
| Novartis Investigative Site | Muscle Shoals | Alabama | 35662 | — |
| Novartis Investigative Site | Little Rock | Arkansas | 72204 | — |
| Novartis Investigative Site | Beverly Hills | California | 90211 | — |
| Novartis Investigative Site | Los Angeles | California | 90073 | — |
| Novartis Investigative Site | Northridge | California | 91325 | — |
| Novartis Investigative Site | Orange | California | 92868 | — |
| Novartis Investigative Site | San Diego | California | 92161 | — |
| Novartis Investigative Site | Santa Ana | California | 92704 | — |
| Novartis Investigative Site | Denver | Colorado | 80220 | — |
| Novartis Investigative Site | Hartford | Connecticut | 06105 | — |
| Novartis Investigative Site | New Haven | Connecticut | 06520-8062 | — |
| Novartis Investigative Site | Stamford | Connecticut | 06905 | — |
| Novartis Investigative Site | West Haven | Connecticut | 06516 | — |
| Novartis Investigative Site | Bradenton | Florida | 34209 | — |
| Novartis Investigative Site | Gainesville | Florida | 32608 | — |
| Novartis Investigative Site | Lake Worth | Florida | 33461 | — |
| Novartis Investigative Site | Miami | Florida | 33143 | — |
| Novartis Investigative Site | Tallahassee | Florida | 32308 | — |
| Novartis Investigative Site | Atlanta | Georgia | 30309 | — |
| Novartis Investigative Site | Atlanta | Georgia | 30310-1495 | — |
| Novartis Investigative Site | Covington | Georgia | 30014 | — |
| Novartis Investigative Site | Cumming | Georgia | 30041 | — |
| Novartis Investigative Site | Chicago | Illinois | 60611 | — |
| Novartis Investigative Site | Chicago | Illinois | 60637 | — |
| Novartis Investigative Site | Evanston | Illinois | 60201 | — |
| Novartis Investigative Site | Hazel Crest | Illinois | 60429 | — |
| Novartis Investigative Site | Lombard | Illinois | 60148 | — |
| Novartis Investigative Site | Maywood | Illinois | 60153 | — |
| Novartis Investigative Site | Oakbrook Terrace | Illinois | 60181 | — |
| Novartis Investigative Site | Peoria | Illinois | 61602 | — |
| Novartis Investigative Site | Quincy | Illinois | 62301 | — |
| Novartis Investigative Site | Louisville | Kentucky | 40206 | — |
| Novartis Investigative Site | Baton Rouge | Louisiana | 70808 | — |
| Novartis Investigative Site | Hammond | Louisiana | 70403 | — |
| Novartis Investigative Site | Lafayette | Louisiana | 70508 | — |
| Novartis Investigative Site | Slidell | Louisiana | 70458 | — |
| Novartis Investigative Site | Biddeford | Maine | 04005 | — |
| Novartis Investigative Site | Portland | Maine | 04102 | — |
| Novartis Investigative Site | Baltimore | Maryland | 21229 | — |
| Novartis Investigative Site | Baltimore | Maryland | 21287 | — |
| Novartis Investigative Site | Columbia | Maryland | 21044 | — |
| Novartis Investigative Site | Boston | Massachusetts | 02118 | — |
| Novartis Investigative Site | Boston | Massachusetts | — | — |
| Novartis Investigative Site | Ann Arbor | Michigan | 48105 | — |
| Novartis Investigative Site | Detroit | Michigan | 48202 | — |
| Novartis Investigative Site | Grand Blanc | Michigan | 48439 | — |
| Novartis Investigative Site | Saginaw | Michigan | 48601 | — |
| Novartis Investigative Site | Minneapolis | Minnesota | 55417 | — |
| Novartis Investigative Site | Minneapolis | Minnesota | 55433 | — |
| Novartis Investigative Site | Minneapolis | Minnesota | 55455 | — |
| Novartis Investigative Site | Saint Cloud | Minnesota | 56303 | — |
| Novartis Investigative Site | Saint Paul | Minnesota | 55102 | — |
| Novartis Investigative Site | Belzoni | Mississippi | 39038 | — |
| Novartis Investigative Site | Jackson | Mississippi | 39216 | — |
| Novartis Investigative Site | St Louis | Missouri | 63110 | — |
| Novartis Investigative Site | St Louis | Missouri | 63136 | — |
| Novartis Investigative Site | Kalispell | Montana | 59901 3158 | — |
| Novartis Investigative Site | Lincoln | Nebraska | 68506 | — |
| Novartis Investigative Site | Lebanon | New Hampshire | 03756 | — |
| Novartis Investigative Site | Morristown | New Jersey | 07960 | — |
| Novartis Investigative Site | New Brunswick | New Jersey | 08901 | — |
| Novartis Investigative Site | Ridgewood | New Jersey | 07450 | — |
| Novartis Investigative Site | Albuquerque | New Mexico | 87102 | — |
| Novartis Investigative Site | Brooklyn | New York | 11215 | — |
| Novartis Investigative Site | Buffalo | New York | 14203 | — |
| Novartis Investigative Site | Buffalo | New York | 14215 | — |
| Novartis Investigative Site | Flushing | New York | 11355 | — |
| Novartis Investigative Site | Kingston | New York | 12401 | — |
| Novartis Investigative Site | Northport | New York | 11768 | — |
| Novartis Investigative Site | Rochester | New York | 14642 | — |
| Novartis Investigative Site | Saratoga Springs | New York | 12866 | — |
| Novartis Investigative Site | The Bronx | New York | 10467 | — |
| Novartis Investigative Site | Chapel Hill | North Carolina | 27599-7075 | — |
| Novartis Investigative Site | Winston-Salem | North Carolina | 27157 | — |
| Novartis Investigative Site | Grand Forks | North Dakota | 58201 | — |
| Novartis Investigative Site | Canton | Ohio | 44710 | — |
| Novartis Investigative Site | Marion | Ohio | 43302 | — |
| Novartis Investigative Site | Tulsa | Oklahoma | 74133 | — |
| Novartis Investigative Site | Portland | Oregon | 97225 | — |
| Novartis Investigative Site | Philadelphia | Pennsylvania | 19107 | — |
| Novartis Investigative Site | Yardley | Pennsylvania | 19067 | — |
| Novartis Investigative Site | Providence | Rhode Island | 02908 | — |
| Novartis Investigative Site | Warwick | Rhode Island | 02886 | — |
| Novartis Investigative Site | Charleston | South Carolina | 29403 | — |
| Novartis Investigative Site | Rapid City | South Dakota | 57701 | — |
| Novartis Investigative Site | Sioux Falls | South Dakota | 57104 | — |
| Novartis Investigative Site | Knoxville | Tennessee | 37917 | — |
| Novartis Investigative Site | Memphis | Tennessee | 38104 | — |
| Novartis Investigative Site | Nashville | Tennessee | 37203 | — |
| Novartis Investigative Site | Nashville | Tennessee | 37212 | — |
| Novartis Investigative Site | Beaumont | Texas | 77702 | — |
| Novartis Investigative Site | Dallas | Texas | 75216 | — |
| Novartis Investigative Site | Dallas | Texas | 75231 | — |
| Novartis Investigative Site | Dallas | Texas | 75235 | — |
| Novartis Investigative Site | Houston | Texas | 77030 | — |
| Novartis Investigative Site | Houston | Texas | 77094 | — |
| Novartis Investigative Site | Livingston | Texas | 77351 | — |
| Novartis Investigative Site | McKinney | Texas | 75069 | — |
| Novartis Investigative Site | San Antonio | Texas | 78234 | — |
| Novartis Investigative Site | Tomball | Texas | 77375 | — |
| Novartis Investigative Site | Salt Lake City | Utah | 84124 | — |
| Novartis Investigative Site | Salt Lake City | Utah | 84132 | — |
| Novartis Investigative Site | White River Junction | Vermont | 05009 | — |
| Novartis Investigative Site | Seattle | Washington | 98122 | — |
| Novartis Investigative Site | Seattle | Washington | 98195 | — |
| Novartis Investigative Site | Madison | Wisconsin | 53705 | — |
| Novartis Investigative Site | Madison | Wisconsin | 53792-1615 | — |
| Novartis Investigative Site | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 605 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01920711, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 29, 2020 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01920711 live on ClinicalTrials.gov.