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Terminated Phase 1 Interventional Accepts healthy volunteers

Effects of Exercise on Memory in Healthy and Brain-Injured Individuals

ClinicalTrials.gov ID: NCT01939769

Public ClinicalTrials.gov record NCT01939769. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 13, 2026, 2:38 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Acute Effects of Exercise on Memory in Healthy and Brain-Injured Individuals

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Background: \- Research has shown that one exercise session may improve a person s ability to recall information they learned before the exercise. Knowing how exercise changes brain activity to improve memory can help researchers understand how memory works and how to improve it in people with memory problems. This study compares two kinds of exercise on a stationary bike for their ability to temporarily improve memory on certain tests. Researchers will look at the effect of exercise on body chemistry by drawing blood and collecting saliva. Objectives: \- To understand how a single session of exercise affects memory testing in healthy people and people who have had traumatic brain injury (TBI). Eligibility: * Adults ages 18 through 45 with TBI. * Healthy adult volunteers, ages 18 through 45. Design: * Participants will be screened with medical history and physical exam. This will take about 1 hour. * Participants with TBI will also be screened with a test of their memory. This will take another hour. * Visit 1 will take about 3 hours. Participants will: \<TAB\>- Have a tube inserted in their arm for drawing blood during the tests. \<TAB\>- Take memory tests. They will look at pictures, symbols, and words, then answer questions. \<TAB\>- Give a saliva sample by chewing on a small sponge for 2 minutes. \<TAB\>- Exercise on a stationary bike. \<TAB\>- Take the memory tests again. \- Visit 2 will take place 1 week later. Participants will take the memory tests only.

Study identification

NCT ID
NCT01939769
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Enrollment
42 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 45 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 30, 2013
Primary completion
May 20, 2015
Completion
Aug 27, 2017
Last update posted
Aug 29, 2017

2013 – 2017

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda Maryland 20892

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01939769, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 29, 2017 · Synced Sep 13, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01939769 live on ClinicalTrials.gov.

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