A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Either Avastin® or Eylea® Compared to Avastin® or Eylea® Monotherapy
Public ClinicalTrials.gov record NCT01940887. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Double-masked, Controlled Trial to Establish the Safety and Efficacy of Intravitreous Administration of Fovista® (Anti PDGF-B Pegylated Aptamer) Administered in Combination With Either Avastin® or Eylea® Compared to Avastin® or Eylea® Monotherapy in Subjects With Subfoveal Neovascular Age-related Macular Degeneration.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objectives of this study are to evaluate the safety and efficacy of intravitreal administration of Fovista® administered in combination with either Avastin® or Eylea® compared to Avastin® or Eylea® monotherapy in subjects with subfoveal choroidal neovascularization secondary to age-related macular degeneration (AMD).
Study identification
- NCT ID
- NCT01940887
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 645 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 2014 (Actual)
- Primary completion
- Jun 2017 (Actual)
- Completion
- Sep 2017 (Actual)
- Last update posted
- Oct 31, 2024
2014 – 2017
United States locations
- U.S. sites
- 100
- U.S. states
- 32
- U.S. cities
- 91
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Gilbert | Arizona | 85295 | — |
| Not listed | Phoenix | Arizona | 85014 | — |
| Not listed | Tucson | Arizona | 85704 | — |
| Not listed | Tucson | Arizona | 85710 | — |
| Not listed | Campbell | California | 95008 | — |
| Not listed | Fresno | California | 93720 | — |
| Not listed | Fullerton | California | 92835 | — |
| Not listed | Irvine | California | 92697 | — |
| Not listed | La Jolla | California | 92037 | — |
| Not listed | Mountain View | California | 94040 | — |
| Not listed | Palm Desert | California | 92211 | — |
| Not listed | Redlands | California | 92374 | — |
| Not listed | Sacramento | California | 95819 | — |
| Not listed | Sacramento | California | 95841 | — |
| Not listed | San Francisco | California | 94109 | — |
| Not listed | Santa Ana | California | 92705 | — |
| Not listed | Ventura | California | 93003 | — |
| Not listed | Aurora | Colorado | 80045 | — |
| Not listed | Colorado Springs | Colorado | 80909 | — |
| Not listed | Denver | Colorado | 80210 | — |
| Not listed | Golden | Colorado | 80401 | — |
| Not listed | Hamden | Connecticut | 06518 | — |
| Not listed | New London | Connecticut | 06320 | — |
| Not listed | Altamonte Springs | Florida | 32701 | — |
| Not listed | Boynton Beach | Florida | 33426 | — |
| Not listed | Fort Lauderdale | Florida | 33308 | — |
| Not listed | Fort Myers | Florida | 33912 | — |
| Not listed | Largo | Florida | 33770 | — |
| Not listed | Melbourne | Florida | 32901 | — |
| Not listed | Palm Beach Gardens | Florida | 33410 | — |
| Not listed | Pensacola | Florida | 32503 | — |
| Not listed | St. Petersburg | Florida | 33711 | — |
| Not listed | Tallahassee | Florida | 32308 | — |
| Not listed | Tampa | Florida | 33609 | — |
| Not listed | Winter Haven | Florida | 33880 | — |
| Not listed | Atlanta | Georgia | 30322 | — |
| Not listed | Augusta | Georgia | 30909 | — |
| Not listed | Marietta | Georgia | 30060 | — |
| Not listed | Oak Forest | Illinois | 60452 | — |
| Not listed | Peoria | Illinois | 61615 | — |
| Not listed | West Des Moines | Iowa | 50266 | — |
| Not listed | Leawood | Kansas | 66211 | — |
| Not listed | Shawnee Mission | Kansas | 66204 | — |
| Not listed | Topeka | Kansas | 66615 | — |
| Not listed | Wichita | Kansas | 67214 | — |
| Not listed | Paducah | Kentucky | 42001 | — |
| Not listed | Baltimore | Maryland | 21209 | — |
| Not listed | Chevy Chase | Maryland | 20815 | — |
| Not listed | Hagerstown | Maryland | 21740 | — |
| Not listed | Towson | Maryland | 21204 | — |
| Not listed | Boston | Massachusetts | 02111 | — |
| Not listed | Boston | Massachusetts | 02114 | — |
| Not listed | Peabody | Massachusetts | 01960 | — |
| Not listed | Worcester | Massachusetts | 01605 | — |
| Not listed | Jackson | Michigan | 49202 | — |
| Not listed | Lansing | Michigan | 48912 | — |
| Not listed | Southfield | Michigan | 48034 | — |
| Not listed | Minneapolis | Minnesota | 55435 | — |
| Not listed | Chesterfield | Missouri | 63017 | — |
| Not listed | St Louis | Missouri | 63110 | — |
| Not listed | St Louis | Missouri | 63128 | — |
| Not listed | Omaha | Nebraska | 68105 | — |
| Not listed | Las Vegas | Nevada | 89144 | — |
| Not listed | Reno | Nevada | 89502 | — |
| Not listed | Lawrenceville | New Jersey | 08648 | — |
| Not listed | Albuquerque | New Mexico | 87109 | — |
| Not listed | New York | New York | 10021 | — |
| Not listed | Rochester | New York | 14620 | — |
| Not listed | Syracuse | New York | 13224 | — |
| Not listed | Asheville | North Carolina | 28803 | — |
| Not listed | Winston-Salem | North Carolina | 27157 | — |
| Not listed | Cleveland | Ohio | 44122 | — |
| Not listed | Cleveland | Ohio | 44130 | — |
| Not listed | Columbus | Ohio | 43212 | — |
| Not listed | Oklahoma City | Oklahoma | 73104 | — |
| Not listed | Portland | Oregon | 97210 | — |
| Not listed | Portland | Oregon | 97239 | — |
| Not listed | Camp Hill | Pennsylvania | 17011 | — |
| Not listed | Philadelphia | Pennsylvania | 19104 | — |
| Not listed | Philadelphia | Pennsylvania | 19107 | — |
| Not listed | West Mifflin | Pennsylvania | 15122 | — |
| Not listed | Ladson | South Carolina | 29456 | — |
| Not listed | West Columbia | South Carolina | 29169 | — |
| Not listed | Rapid City | South Dakota | 57701 | — |
| Not listed | Abilene | Texas | 79606 | — |
| Not listed | Amarillo | Texas | 79106 | — |
| Not listed | Dallas | Texas | 75231 | — |
| Not listed | Fort Worth | Texas | 43212 | — |
| Not listed | McAllen | Texas | 78503 | — |
| Not listed | Plano | Texas | 75093 | — |
| Not listed | San Antonio | Texas | 78233 | — |
| Not listed | San Antonio | Texas | 78240 | — |
| Not listed | Willow Park | Texas | 76087 | — |
| Not listed | Salt Lake City | Utah | 84107 | — |
| Not listed | Salt Lake City | Utah | 84132 | — |
| Not listed | Richmond | Virginia | 23235 | — |
| Not listed | Virginia Beach | Virginia | 23462 | — |
| Not listed | Bellevue | Washington | 98004 | — |
| Not listed | Silverdale | Washington | 98383 | — |
| Not listed | Morgantown | West Virginia | 25606 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 107 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01940887, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 31, 2024 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01940887 live on ClinicalTrials.gov.