A Clinical Trial to Evaluate the HeartWare™ Ventricular Assist System (ENDURANCE SUPPLEMENTAL TRIAL)
Public ClinicalTrials.gov record NCT01966458. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Prospective, Randomized, Controlled, Unblinded, Multi-Center Clinical Trial to Evaluate the HeartWare™ Ventricular Assist Device System for Destination Therapy of Advanced Heart Failure
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a prospective, randomized, controlled, unblinded, multi-center evaluation of safety and efficacy in patients implanted with a HeartWare® HVAD who receive improved blood pressure management. Subjects have chronic Stage D or NYHA Class IIIB/IV left ventricular failure who have received and failed optimal medical therapy, and who are ineligible for cardiac transplantation.
Study identification
- NCT ID
- NCT01966458
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 494 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2013 (Actual)
- Primary completion
- Aug 2016 (Actual)
- Completion
- Aug 2020 (Actual)
- Last update posted
- Oct 23, 2020
2013 – 2020
United States locations
- U.S. sites
- 47
- U.S. states
- 26
- U.S. cities
- 40
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Mayo Clinic (Arizona) | Phoenix | Arizona | 85054 | — |
| The University of Southern California | Los Angeles | California | 90033 | — |
| Cedars Sinai Medical Center | Los Angeles | California | 90048 | — |
| Stanford University School of Medicine | Stanford | California | 94305 | — |
| Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| University of Florida Gainesville | Gainesville | Florida | 32610 | — |
| University of Miami / Jackson Memorial Hospital | Miami | Florida | 33136 | — |
| Tampa Transplant Institute/Tampa General Hospital | Tampa | Florida | 33606 | — |
| The Emory Clinic Inc. | Atlanta | Georgia | 30322 | — |
| Saint Joseph Hospital of Atlanta | Atlanta | Georgia | 30342 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Advocate Christ Medical Center | Oak Lawn | Illinois | 60453 | — |
| IU Health Methodist | Indianapolis | Indiana | 46202 | — |
| St. Vincent Health | Indianapolis | Indiana | 46260 | — |
| Jewish Hospital | Louisville | Kentucky | 40202 | — |
| John Ochsner Heart & Vascular Institute | New Orleans | Louisiana | 70115 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Johns Hopkins Hospital | Baltimore | Maryland | 21287 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| University of Michigan Hospital | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Abbott Northwestern | Minneapolis | Minnesota | 55407 | — |
| Mayo Clinic / St. Marys Hospital | Rochester | Minnesota | 55902 | — |
| Washington University / Barnes Jewish Hospital | St Louis | Missouri | 63110 | — |
| New York Presbyterian Hospital/Columbia | New York | New York | 10032 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Cleveland Clinic Foundatiojn | Cleveland | Ohio | 44195 | — |
| Ohio State University Medical Center | Columbus | Ohio | 43210 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| University of Pennsylvania Hospital | Philadelphia | Pennsylvania | 19104 | — |
| UPMC Presbyterian | Pittsburgh | Pennsylvania | 15213 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232-8802 | — |
| Baylor University Medical Center | Dallas | Texas | 75246 | — |
| UT Southwestern Medical Center at Dallas | Dallas | Texas | 75390 | — |
| Texas Heart Institute | Houston | Texas | 77030 | — |
| The Methodist Hospital | Houston | Texas | 77030 | — |
| Intermountain Medical Center | Murray | Utah | 84107 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| Inova Fairfax Hospital | Falls Church | Virginia | 22042 | — |
| Sentara Norfolk | Norfolk | Virginia | 23507 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
| Northwest Cardiothoracic &Transplant Surgeons | Spokane | Washington | 99204 | — |
| Aurora St. Luke's Medical Center | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01966458, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 23, 2020 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01966458 live on ClinicalTrials.gov.