Effect of Isotretinoin on Immune Activation Among HIV-1 Infected Subjects With Incomplete CD4+ T Cell Recovery
Public ClinicalTrials.gov record NCT01969058. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Prospective Randomized Controlled Study to Evaluate the Effect of Isotretinoin on Immune Activation Among HIV-1 Infected Subjects With Incomplete CD4+ T Cell Recovery on Suppressive Antiretroviral Therapy (ART)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This phase II study was done in HIV-infected participants on antiretroviral therapy to evaluate the effects of isotretinoin (a drug that is approved for use in the treatment of severe acne) on the immune system. The immune system helps the body fight infections. When the immune system is not working well, one may be at greater risk for diseases that are common in aging, like heart disease, weaker bones, and kidney disease.
Study identification
- NCT ID
- NCT01969058
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 76 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 2, 2014 (Actual)
- Primary completion
- Aug 31, 2016 (Actual)
- Completion
- Nov 2016 (Actual)
- Last update posted
- Oct 15, 2024
2014 – 2016
United States locations
- U.S. sites
- 14
- U.S. states
- 11
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| 31788 Alabama CRS | Birmingham | Alabama | 35294 | — |
| 601 University of California, Los Angeles CARE Center CRS | Los Angeles | California | 90035 | — |
| 801 University of California, San Francisco HIV/AIDS CRS | San Francisco | California | 94110 | — |
| 101 Massachusetts General Hospital (MGH) CRS | Boston | Massachusetts | 02114 | — |
| 107 Brigham and Women's Hosp. ACTG CRS | Boston | Massachusetts | 02115 | — |
| 2101 Washington University Therapeutics (WT) CRS | St Louis | Missouri | 63110 | — |
| 31786 New Jersey Medical School Clinical Research Center CRS | Newark | New Jersey | 07103 | — |
| 31787 University of Rochester Adult HIV Therapeutic Strategies Network CRS | Rochester | New York | 14642 | — |
| 3201 Chapel Hill CRS | Chapel Hill | North Carolina | 27516 | — |
| 3203 Greensboro CRS | Greensboro | North Carolina | 27401 | — |
| 2401 Cincinnati CRS | Cincinnati | Ohio | 45267-0405 | — |
| 2951 The Miriam Hospital (TMH) ACTG CRS | Providence | Rhode Island | 02906 | — |
| 3652 Vanderbilt Therapeutics (VT) CRS | Nashville | Tennessee | 37204 | — |
| 31473 Houston AIDS Research Team (HART) CRS | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01969058, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 15, 2024 · Synced Nov 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01969058 live on ClinicalTrials.gov.