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Completed Phase 2 Interventional Results available

Study of the Combination Therapy of Rt-PA and Eptifibatide to Treat Acute Ischemic Stroke (CLEAR-FDR)

ClinicalTrials.gov ID: NCT01977456

Public ClinicalTrials.gov record NCT01977456. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 2:18 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 2 The Combined Approach to Lysis Utilizing Eptifibatide and Rt-PA in Acute Ischemic Stroke-Full Dose Regimen(CLEAR-FDR)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary goal of this trial is to determine if individuals with acute ischemic stroke treated with a full dose of IV recombinant tissue plasminogen activator (rt-PA) plus IV eptifibatide started within 3 hours of symptom onset are more likely to have a better outcome than individuals treated with standard IV rt-PA alone.

Study identification

NCT ID
NCT01977456
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Arthur Pancioli
Other
Enrollment
27 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 31, 2013
Primary completion
Dec 31, 2014
Completion
Mar 31, 2015
Last update posted
Jan 20, 2016

2013 – 2015

United States locations

U.S. sites
8
U.S. states
2
U.S. cities
4
Facility City State ZIP Site status
St. Elizabeth Healthcare System Edgewood Edgewood Kentucky 41017
St. Elizabeth Healthcare Florence Florence Kentucky 41042
St. Elizabeth Healthcare Ft. Thomas Fort Thomas Kentucky 41075
The Christ Hospital Cincinnati Ohio 45219
University of Cincinnati Medical Center Cincinnati Ohio 45219
Good Samaritan Hospital Cincinnati Ohio 45220
Jewish Hospital Cincinnati Ohio 45236
Bethesda North Hospital Cincinnati Ohio 45242

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01977456, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 20, 2016 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01977456 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →