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Completed Phase 1Phase 2 Interventional Results available

Phase 1b/2 Study of Carfilzomib, Carboplatin, and Etoposide in Patients With Previously Untreated Extensive Stage Small-cell Lung Cancer

ClinicalTrials.gov ID: NCT01987232

Public ClinicalTrials.gov record NCT01987232. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 11, 2026, 12:57 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 1b/2, Multicenter, Open-label Study of Carfilzomib, Carboplatin, and Etoposide in Subjects With Previously Untreated Extensive-stage Small-cell Lung Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine the maximum tolerated dose and assess the safety, tolerability and activity of carfilzomib given in combination with carboplatin and etoposide as initial therapy for patients with extensive-stage small-cell lung cancer (ES SCLC).

Study identification

NCT ID
NCT01987232
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Amgen
Industry
Enrollment
32 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 4, 2013
Primary completion
Jul 31, 2016
Completion
May 3, 2017
Last update posted
Aug 27, 2017

2013 – 2017

United States locations

U.S. sites
11
U.S. states
8
U.S. cities
11
Facility City State ZIP Site status
Yale University, Yale Cancer Center New Haven Connecticut
UF Health Davis Cancer Pavilion and Shands Med Plaza Gainesville Florida
Goshen Center for Cancer Care Goshen Indiana
Horizon Oncology Research, Inc. Lafayette Indiana
Indiana University Health Ball Memorial Hospital Muncie Indiana
Baptist Health Lexington Clinical Research Center Lexington Kentucky
Frederick Memorial Hospital Frederick Maryland
John Theurer Cancer Center at Hackensack UMC Hackensack New Jersey
Levine Cancer Institute Charlotte North Carolina
Wake Forest Baptist Health Winston-Salem North Carolina
The University of Texas MD Anderson Cancer Center Houston Texas

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01987232, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 27, 2017 · Synced Sep 11, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01987232 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →