ClinicalTrials.gov record
A Study Comparing Cardiovascular Effects of Ticagrelor Versus Placebo in Patients With Type 2 Diabetes Mellitus
ClinicalTrials.gov ID: NCT01991795
Public ClinicalTrials.gov record NCT01991795. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multinational, Randomised, Double-Blind, Placebo-Controlled Trial to Evaluate the Effect of Ticagrelor Twice Daily on the Incidence of Cardiovascular Death, Myocardial Infarction or Stroke in Patients With Type 2 Diabetes Mellitus (THEMIS - Effect of Ticagrelor on Health Outcomes in Diabetes Mellitus Patients Intervention Study).
Study identification
- NCT ID
- NCT01991795
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- AstraZeneca
- Industry
- Enrollment
- 19,271 participants
Conditions and interventions
Conditions
Interventions
- Ticagrelor 60 mg Drug
- Ticagrelor placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years to 130 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 9, 2014
- Primary completion
- Jan 24, 2019
- Completion
- Jan 24, 2019
- Last update posted
- Mar 17, 2020
2014 – 2019
United States locations
- U.S. sites
- 295
- U.S. states
- 44
- U.S. cities
- 241
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site | Alexander City | Alabama | 35010 | — |
| Research Site | Birmingham | Alabama | 35211 | — |
| Research Site | Fairhope | Alabama | 36532 | — |
| Research Site | Huntsville | Alabama | 35801 | — |
| Research Site | Huntsville | Alabama | 35803 | — |
| Research Site | Mobile | Alabama | 36608 | — |
| Research Site | Montgomery | Alabama | 36111 | — |
| Research Site | Sheffield | Alabama | 35660 | — |
| Research Site | Tuscumbia | Alabama | 35674 | — |
| Research Site | Cottonwood | Arizona | 86326 | — |
| Research Site | Glendale | Arizona | 85306 | — |
| Research Site | Tucson | Arizona | 85741 | — |
| Research Site | Little Rock | Arkansas | 72204 | — |
| Research Site | Little Rock | Arkansas | 72205 | — |
| Research Site | Little Rock | Arkansas | 72211 | — |
| Research Site | Anaheim | California | 92801 | — |
| Research Site | Bakersfield | California | 93309 | — |
| Research Site | Beverly Hills | California | 90211 | — |
| Research Site | Fremont | California | 94538 | — |
| Research Site | Fresno | California | 93721 | — |
| Research Site | Irvine | California | 92614 | — |
| Research Site | La Mesa | California | 91942 | — |
| Research Site | Long Beach | California | 90806 | — |
| Research Site | Long Beach | California | 90807 | — |
| Research Site | Los Alamitos | California | 90720 | — |
| Research Site | Los Angeles | California | 90033 | — |
| Research Site | Los Angeles | California | 90036 | — |
| Research Site | Los Angeles | California | 90067 | — |
| Research Site | Mission Hills | California | 91345 | — |
| Research Site | Newport Beach | California | 92663 | — |
| Research Site | Sacramento | California | 95821 | — |
| Research Site | San Diego | California | 92103 | — |
| Research Site | San Diego | California | 92122 | — |
| Research Site | Stanford | California | 94305-5235 | — |
| Research Site | Stockton | California | 95204 | — |
| Research Site | Tarzana | California | 91356 | — |
| Research Site | Torrance | California | 90509 | — |
| Research Site | Denver | Colorado | 80239-3133 | — |
| Research Site | Bridgeport | Connecticut | 06610 | — |
| Research Site | Greenwich | Connecticut | 06830 | — |
| Research Site | Bradenton | Florida | 34209 | — |
| Research Site | Clearwater | Florida | 33756 | — |
| Research Site | Cooper City | Florida | 33024 | — |
| Research Site | Coral Springs | Florida | 33065 | — |
| Research Site | Crystal River | Florida | 34429 | — |
| Research Site | Cutler Bay | Florida | 33189 | — |
| Research Site | Daytona Beach | Florida | 32114 | — |
| Research Site | DeLand | Florida | 32720 | — |
| Research Site | Fort Lauderdale | Florida | 33312 | — |
| Research Site | Hialeah | Florida | 33012 | — |
| Research Site | Hialeah | Florida | 33013 | — |
| Research Site | Hollywood | Florida | 33021 | — |
| Research Site | Jacksonville | Florida | 32204 | — |
| Research Site | Jacksonville | Florida | 32209 | — |
| Research Site | Jacksonville | Florida | 32216 | — |
| Research Site | Lake Worth | Florida | 33467 | — |
| Research Site | Largo | Florida | 33707 | — |
| Research Site | Merritt Island | Florida | 32953 | — |
| Research Site | Miami | Florida | 33126 | — |
| Research Site | Miami | Florida | 33134 | — |
| Research Site | Miami | Florida | 33135 | — |
| Research Site | Miami | Florida | 33136 | — |
| Research Site | Miami | Florida | 33144 | — |
| Research Site | Miami | Florida | 33155 | — |
| Research Site | Miami | Florida | 33165 | — |
| Research Site | Miami | Florida | 33166 | — |
| Research Site | Miami | Florida | 33173 | — |
| Research Site | Miami | Florida | 33174 | — |
| Research Site | Miami | Florida | 33176 | — |
| Research Site | Miami | Florida | 33186 | — |
| Research Site | Miami Gardens | Florida | 33169 | — |
| Research Site | Miami Shores | Florida | 33012 | — |
| Research Site | Miami Springs | Florida | 33166 | — |
| Research Site | Naples | Florida | 34102 | — |
| Research Site | New Smyrna Beach | Florida | 32169 | — |
| Research Site | North Miami Beach | Florida | 33162 | — |
| Research Site | Ocala | Florida | 34471 | — |
| Research Site | Ormond Beach | Florida | 32174 | — |
| Research Site | Panama City | Florida | 32401 | — |
| Research Site | Port Charlotte | Florida | 33952 | — |
| Research Site | Saint Cloud | Florida | 34769 | — |
| Research Site | Atlanta | Georgia | 30322 | — |
| Research Site | Columbus | Georgia | 31904 | — |
| Research Site | Cumming | Georgia | 30041 | — |
| Research Site | Decatur | Georgia | 30012 | — |
| Research Site | Decatur | Georgia | 30032 | — |
| Research Site | Gainesville | Georgia | 30501 | — |
| Research Site | Tucker | Georgia | 30084 | — |
| Research Site | Nampa | Idaho | 83687 | — |
| Research Site | Arlington Heights | Illinois | 60005 | — |
| Research Site | Chicago | Illinois | 60631 | — |
| Research Site | Chicago | Illinois | 60654 | — |
| Research Site | Crystal Lake | Illinois | 60012 | — |
| Research Site | Elmhurst | Illinois | 60126 | — |
| Research Site | Evanston | Illinois | 60201 | — |
| Research Site | Gurnee | Illinois | 60031 | — |
| Research Site | Hinsdale | Illinois | 60521 | — |
| Research Site | Moline | Illinois | 61265 | — |
| Research Site | North Chicago | Illinois | 60064 | — |
| Research Site | Peoria | Illinois | 61614 | — |
| Research Site | Anderson | Indiana | 46011 | — |
| Research Site | Elkhart | Indiana | 46514 | — |
| Research Site | Fort Wayne | Indiana | 46845 | — |
| Research Site | Greenfield | Indiana | 46140 | — |
| Research Site | Indianapolis | Indiana | 460202 | — |
| Research Site | Indianapolis | Indiana | 46227 | — |
| Research Site | Muncie | Indiana | 47303 | — |
| Research Site | Muncie | Indiana | 47304 | — |
| Research Site | Munster | Indiana | 46321 | — |
| Research Site | Davenport | Iowa | 52803 | — |
| Research Site | West Des Moines | Iowa | 50265 | — |
| Research Site | Wichita | Kansas | 67214 | — |
| Research Site | Crestview Hills | Kentucky | 41017 | — |
| Research Site | Owensboro | Kentucky | 42303 | — |
| Research Site | Alexandria | Louisiana | 71301 | — |
| Research Site | Bossier City | Louisiana | 71111 | — |
| Research Site | Covington | Louisiana | 70433 | — |
| Research Site | Crowley | Louisiana | 70526 | — |
| Research Site | Minden | Louisiana | 71055 | — |
| Research Site | Monroe | Louisiana | 71201 | — |
| Research Site | Shreveport | Louisiana | 71103 | — |
| Research Site | Shreveport | Louisiana | 71105 | — |
| Research Site | Slidell | Louisiana | 70458 | — |
| Research Site | Auburn | Maine | 04210 | — |
| Research Site | Bangor | Maine | 04401 | — |
| Research Site | Baltimore | Maryland | 21215-5271 | — |
| Research Site | Baltimore | Maryland | 21218 | — |
| Research Site | Bowie | Maryland | 20715 | — |
| Research Site | Glen Burnie | Maryland | 21061 | — |
| Research Site | Greenbelt | Maryland | 20770 | — |
| Research Site | Oxon Hill | Maryland | 20745 | — |
| Research Site | Prince Frederick | Maryland | 20678 | — |
| Research Site | Salisbury | Maryland | 21804 | — |
| Research Site | Haverhill | Massachusetts | 01830 | — |
| Research Site | North Attleboro | Massachusetts | 02760 | — |
| Research Site | Detroit | Michigan | 48202 | — |
| Research Site | Jackson | Michigan | 49201 | — |
| Research Site | Kalamazoo | Michigan | 49009 | — |
| Research Site | Mount Clemens | Michigan | 48043 | — |
| Research Site | Petoskey | Michigan | 49770 | — |
| Research Site | Pontiac | Michigan | 48341 | — |
| Research Site | Rochester Hills | Michigan | 48307 | — |
| Research Site | Troy | Michigan | 48098 | — |
| Research Site | Duluth | Minnesota | 55805 | — |
| Research Site | Saint Paul | Minnesota | 55102 | — |
| Research Site | Biloxi | Mississippi | 39531 | — |
| Research Site | Jackson | Mississippi | 39216 | — |
| Research Site | Olive Branch | Mississippi | 38654 | — |
| Research Site | Tupelo | Mississippi | 38801 | — |
| Research Site | Joplin | Missouri | 64804 | — |
| Research Site | Kansas City | Missouri | 64108 | — |
| Research Site | Kansas City | Missouri | 64111 | — |
| Research Site | Lee's Summit | Missouri | 64064 | — |
| Research Site | North Kansas City | Missouri | 64116 | — |
| Research Site | St Louis | Missouri | 63110 | — |
| Research Site | St Louis | Missouri | 63128 | — |
| Research Site | St Louis | Missouri | 63136 | — |
| Research Site | Helena | Montana | 59601 | — |
| Research Site | Hastings | Nebraska | 68901 | — |
| Research Site | Lincoln | Nebraska | 68506 | — |
| Research Site | Lincoln | Nebraska | 68526 | — |
| Research Site | Las Vegas | Nevada | 89128 | — |
| Research Site | Bridgewater | New Jersey | 08807 | — |
| Research Site | East Brunswick | New Jersey | 08816 | — |
| Research Site | Flemington | New Jersey | 08822 | — |
| Research Site | Morristown | New Jersey | 08057 | — |
| Research Site | Somerset | New Jersey | 08873 | — |
| Research Site | Toms River | New Jersey | 08755 | — |
| Research Site | Voorhees Township | New Jersey | 08043 | — |
| Research Site | Albuquerque | New Mexico | 87102 | — |
| Research Site | Albany | New York | 12203 | — |
| Research Site | Binghamton | New York | 13901 | — |
| Research Site | Buffalo | New York | 14215 | — |
| Research Site | Hawthorne | New York | 10532 | — |
| Research Site | Manhasset | New York | 11030 | — |
| Research Site | New Windsor | New York | 12553 | — |
| Research Site | New York | New York | 10001 | — |
| Research Site | New York | New York | 10029 | — |
| Research Site | Orchard Park | New York | 14127 | — |
| Research Site | Poughkeepsie | New York | 12601 | — |
| Research Site | Saratoga Springs | New York | 12866 | — |
| Research Site | Stony Brook | New York | 11794-8167 | — |
| Research Site | The Bronx | New York | 10467 | — |
| Research Site | Utica | New York | 13501 | — |
| Research Site | Asheville | North Carolina | 28803 | — |
| Research Site | Calabash | North Carolina | 28467 | — |
| Research Site | Cary | North Carolina | 27518 | — |
| Research Site | Clayton | North Carolina | 27520 | — |
| Research Site | High Point | North Carolina | 27265 | — |
| Research Site | Lenoir | North Carolina | 28645 | — |
| Research Site | Morganton | North Carolina | 28655 | — |
| Research Site | Pinehurst | North Carolina | 28374 | — |
| Research Site | Raleigh | North Carolina | 27610 | — |
| Research Site | Rocky Mount | North Carolina | 27804 | — |
| Research Site | Sanford | North Carolina | 27330 | — |
| Research Site | Smithfield | North Carolina | 27577 | — |
| Research Site | Tabor City | North Carolina | 28463 | — |
| Research Site | Winston-Salem | North Carolina | 27103 | — |
| Research Site | Fargo | North Dakota | 58103 | — |
| Research Site | Fargo | North Dakota | 58104 | — |
| Research Site | Akron | Ohio | 44302 | — |
| Research Site | Canton | Ohio | 44710 | — |
| Research Site | Cincinnati | Ohio | 45227 | — |
| Research Site | Cleveland | Ohio | 44122 | — |
| Research Site | Cleveland | Ohio | 44126 | — |
| Research Site | Dayton | Ohio | 45419 | — |
| Research Site | Kettering | Ohio | 45429 | — |
| Research Site | Lyndhurst | Ohio | 44124 | — |
| Research Site | Springfield | Ohio | 45504 | — |
| Research Site | Willoughby | Ohio | 44094 | — |
| Research Site | Youngstown | Ohio | 44501 | — |
| Research Site | Oklahoma City | Oklahoma | 73103 | — |
| Research Site | Oklahoma City | Oklahoma | 73104 | — |
| Research Site | Oklahoma City | Oklahoma | 73129 | — |
| Research Site | Hillsboro | Oregon | 97123-4117 | — |
| Research Site | Medford | Oregon | 97504 | — |
| Research Site | Butler | Pennsylvania | 16001 | — |
| Research Site | Camp Hill | Pennsylvania | 17011 | — |
| Research Site | Danville | Pennsylvania | 17822 | — |
| Research Site | Doylestown | Pennsylvania | 18901 | — |
| Research Site | Erie | Pennsylvania | 16502 | — |
| Research Site | Harleysville | Pennsylvania | 19438 | — |
| Research Site | Indiana | Pennsylvania | 15701 | — |
| Research Site | Newport | Pennsylvania | 17074 | — |
| Research Site | Philadelphia | Pennsylvania | 19141 | — |
| Research Site | Pittsburgh | Pennsylvania | 15240 | — |
| Research Site | Port Matilda | Pennsylvania | 16870 | — |
| Research Site | Scranton | Pennsylvania | 18510 | — |
| Research Site | Wyomissing | Pennsylvania | 19610 | — |
| Research Site | Yardley | Pennsylvania | 19067 | — |
| Research Site | Providence | Rhode Island | 02903 | — |
| Research Site | Providence | Rhode Island | 02906 | — |
| Research Site | Columbia | South Carolina | 29204 | — |
| Research Site | Columbia | South Carolina | 29205 | — |
| Research Site | Columbia | South Carolina | 29209-1639 | — |
| Research Site | Greenwood | South Carolina | 29646 | — |
| Research Site | North Myrtle Beach | South Carolina | 29582 | — |
| Research Site | Rock Hill | South Carolina | 29732 | — |
| Research Site | Simpsonville | South Carolina | 29681 | — |
| Research Site | Varnville | South Carolina | 29924 | — |
| Research Site | Rapid City | South Dakota | 57701 | — |
| Research Site | Sioux Falls | South Dakota | 57108 | — |
| Research Site | Bristol | Tennessee | 37620 | — |
| Research Site | Jackson | Tennessee | 38305 | — |
| Research Site | Knoxville | Tennessee | 37917 | — |
| Research Site | Knoxville | Tennessee | 37934 | — |
| Research Site | Nashville | Tennessee | 37204 | — |
| Research Site | Tullahoma | Tennessee | 37388 | — |
| Research Site | Amarillo | Texas | 79106 | — |
| Research Site | Arlington | Texas | 76012 | — |
| Research Site | Austin | Texas | 78705 | — |
| Research Site | Austin | Texas | 78709 | — |
| Research Site | Beaumont | Texas | 77702 | — |
| Research Site | Channelview | Texas | 77530 | — |
| Research Site | Dallas | Texas | 75216 | — |
| Research Site | Dallas | Texas | 75231 | — |
| Research Site | Dallas | Texas | 75390-9184 | — |
| Research Site | Fort Sam Houston | Texas | 78234 | — |
| Research Site | Fort Worth | Texas | 76107 | — |
| Research Site | Fort Worth | Texas | 76116 | — |
| Research Site | Georgetown | Texas | 78626 | — |
| Research Site | Houston | Texas | 77024 | — |
| Research Site | Houston | Texas | 77025 | — |
| Research Site | Houston | Texas | 77036 | — |
| Research Site | Houston | Texas | 77043 | — |
| Research Site | Houston | Texas | 77058 | — |
| Research Site | Houston | Texas | 77062 | — |
| Research Site | Houston | Texas | 77070 | — |
| Research Site | Houston | Texas | 77090 | — |
| Research Site | Huntsville | Texas | 77340 | — |
| Research Site | Katy | Texas | 77450 | — |
| Research Site | Kingwood | Texas | 77339 | — |
| Research Site | Lubbock | Texas | 79430 | — |
| Research Site | McAllen | Texas | 78503 | — |
| Research Site | Pharr | Texas | 78577 | — |
| Research Site | Plano | Texas | 75024 | — |
| Research Site | Plano | Texas | 75093 | — |
| Research Site | San Antonio | Texas | 78224 | — |
| Research Site | San Antonio | Texas | 78231 | — |
| Research Site | Shavano Park | Texas | 78231 | — |
| Research Site | Bountiful | Utah | 84010 | — |
| Research Site | Draper | Utah | 84020 | — |
| Research Site | Salt Lake City | Utah | 84124 | — |
| Research Site | Alexandria | Virginia | 22304 | — |
| Research Site | Arlington | Virginia | 22205 | — |
| Research Site | Danville | Virginia | 24541 | — |
| Research Site | Falls Church | Virginia | 22042 | — |
| Research Site | Manassas | Virginia | 20109 | — |
| Research Site | Manassas | Virginia | 20110 | — |
| Research Site | Roanoke | Virginia | 24014 | — |
| Research Site | Port Orchard | Washington | 98366 | — |
| Research Site | Seattle | Washington | 98104 | — |
| Research Site | Huntington | West Virginia | 25701 | — |
| Research Site | Kenosha | Wisconsin | 53144 | — |
| Research Site | Waukesha | Wisconsin | 53188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 942 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01991795, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 17, 2020 · Synced Jul 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01991795 live on ClinicalTrials.gov.