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Completed Phase 1Phase 2 Interventional Results available

A Study of Polatuzumab Vedotin in Combination With Rituximab or Obinutuzumab, Cyclophosphamide, Doxorubicin, and Prednisone in Participants With B-Cell Non-Hodgkin's Lymphoma

ClinicalTrials.gov ID: NCT01992653

Public ClinicalTrials.gov record NCT01992653. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 11, 2026, 12:43 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase Ib/II Study Evaluating the Safety, Tolerability and Anti-Tumor Activity of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab, Cyclophosphamide, Doxorubicin, and Prednisone in Patients With B-Cell Non-Hodgkin's Lymphoma

Study identification

NCT ID
NCT01992653
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Genentech, Inc.
Industry
Enrollment
85 participants

Conditions and interventions

Interventions

  • Cyclophosphamide Drug
  • Doxorubicin Drug
  • Obinutuzumab Drug
  • Polatuzumab Vedotin Drug
  • Prednisolone Drug
  • Prednisone Drug
  • Rituximab Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 28, 2013
Primary completion
Dec 18, 2018
Completion
Dec 18, 2018
Last update posted
Mar 13, 2023

2013 – 2018

United States locations

U.S. sites
7
U.S. states
5
U.S. cities
6
Facility City State ZIP Site status
The University of Alabama at Birmingham Birmingham Alabama 35233
Banner MD Anderson Cancer Center Greeley Colorado 85234
Washington University; Pediatrics St Louis Missouri 63110
Northwest Cancer Specialists Portland Oregon 97210
Oregon Health and Science University Portland Oregon 97239
Willamette Valley Clinical Studies; Cancer Institute Springfield Oregon 97477
Blue Ridge Cancer Care Roanoke Virginia 24014

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT01992653, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 13, 2023 · Synced May 11, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT01992653 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →