A Phase 2, Multi-Center Study To Compare The Efficacy And Safety Of A Chemokine CCR2/5 Receptor Antagonist With Ranibizumab In Adults With Diabetic Macular Edema
Public ClinicalTrials.gov record NCT01994291. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Masked, Placebo-Controlled, Parallel Group, Multi-Center Study To Compare The Efficacy And Safety Of A Chemokine CCR2/5 Receptor Antagonist (PF-04634817) With That Of Ranibizumab In Adult Subjects With Diabetic Macular Edema
Study identification
- NCT ID
- NCT01994291
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Pfizer
- Industry
- Enrollment
- 199 participants
Conditions and interventions
Conditions
Interventions
- Masked Sham Therapy Drug
- PF-04634817 Drug
- Placebo Drug
- Ranibizumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 31, 2013
- Primary completion
- Jul 31, 2015
- Completion
- Jul 31, 2015
- Last update posted
- Oct 16, 2016
2013 – 2015
United States locations
- U.S. sites
- 33
- U.S. states
- 15
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retina Research Institute, LLC | Phoenix | Arizona | 85014 | — |
| Retinal Consultants of Arizona | Phoenix | Arizona | 85014 | — |
| Sunny View Medical Center | Phoenix | Arizona | 85018 | — |
| Premier Research Group Limited | Phoenix | Arizona | 85027 | — |
| Retina Centers, P.C. | Tucson | Arizona | 85704 | — |
| Retina Institute of California | Arcadia | California | 91007 | — |
| Retina Vitreous Associates Medical Group | Beverly Hills | California | 90211 | — |
| Retinal Diagnostic Center | Campbell | California | 95008 | — |
| Retina Associates of Orange County | Laguna Hills | California | 92653 | — |
| Southern California Desert Retina Consultants | Palm Desert | California | 92211 | — |
| American Institute of Research (Administrative Only) | Whittier | California | 90603 | — |
| New England Retina Associates | New London | Connecticut | 06320 | — |
| Bascom Palmer Eye Institute | Miami | Florida | 33136 | — |
| Fort Lauderdale Eye Institute | Plantation | Florida | 33324 | — |
| Center for Retina and Macular Disease | Winter Haven | Florida | 33880 | — |
| Southeast Retina Center, PC | Augusta | Georgia | 30909 | — |
| Midwest Eye Institute | Indianapolis | Indiana | 46290 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| TLC Eyecare & Laser Center | Jackson | Michigan | 49202 | — |
| Wm Beaumont Medical Office Building | Royal Oak | Michigan | 48073 | — |
| Charlotte Eye Ear Nose and Throat Associates PA | Charlotte | North Carolina | 28210 | — |
| Retina Associates of Cleveland, Inc. | Cleveland | Ohio | 44122 | — |
| Retina Associates of Cleveland | Youngstown | Ohio | 44505 | — |
| Dean McGee Eye Institute | Oklahoma City | Oklahoma | 73104 | — |
| University of Oklahoma -OU Physicians | Oklahoma City | Oklahoma | 73104 | — |
| Retina Vitreous Consultants | Pittsburgh | Pennsylvania | 15213 | — |
| Associates in Ophthalmology Ltd | West Mifflin | Pennsylvania | 15122 | — |
| Black Hills Regional Eye Institute | Rapid City | South Dakota | 57701 | — |
| Brain B.Berger,MD,PA | Austin | Texas | 78705 | — |
| Retina Research Center | Austin | Texas | 78705 | — |
| Retina Consultants of Houston, PA | Houston | Texas | 77030 | — |
| Medical Center Ophthalmology Associates | San Antonio | Texas | 78240 | — |
| Rocky Mountain Retina Consultants | Salt Lake City | Utah | 84107 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 30 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01994291, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 16, 2016 · Synced May 11, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT01994291 live on ClinicalTrials.gov.