ClinicalTrials.gov record
Lenalidomide Plus Rituximab Followed by Lenalidomide Versus Rituximab Maintenance for Relapsed/Refractory Follicular, Marginal Zone or Mantle Cell Lymphoma.
ClinicalTrials.gov ID: NCT01996865
Public ClinicalTrials.gov record NCT01996865. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3B Randomized Study of Lenalidomide (CC-5013) Plus Rituximab Maintenance Therapy Followed by Lenalidomide Single-Agent Maintenance Versus Rituximab Maintenance in Subjects With Relapsed/Refractory Follicular, Marginal Zone, or Mantle Cell Lymphoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Follicular lymphoma (FL), marginal zone lymphoma (MZL), and mantle cell lymphoma (MCL) are distinct histologic types of B-cell NHL. Lenalidomide is an immunomodulatory agent with direct and immune-mediated mechanisms of action, as well as clinical activity in NHL. Recent studies in frontline and relapsed/refractory NHL show high activity for lenalidomide plus rituximab (R2), supporting further study of this combination.
Study identification
- NCT ID
- NCT01996865
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 503 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 1, 2014 (Actual)
- Primary completion
- May 11, 2024 (Actual)
- Completion
- Sep 17, 2024 (Actual)
- Last update posted
- Jul 10, 2025
2014 – 2024
United States locations
- U.S. sites
- 110
- U.S. states
- 35
- U.S. cities
- 103
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 055 | Tucson | Arizona | 85710 | — |
| Local Institution - 077 | Little Rock | Arkansas | 72205 | — |
| Local Institution - 079 | Berkeley | California | 94704 | — |
| Local Institution - 142 | Concord | California | 94520 | — |
| Bay Area Cancer Research Group, LLC | Pleasant Hill | California | 94523 | — |
| Sutter Hematology and Oncology | Sacramento | California | 95816 | — |
| Local Institution - 032 | San Diego | California | 92123 | — |
| Local Institution - 130 | Santa Barbara | California | 93105 | — |
| Local Institution - 052 | Boulder | Colorado | 80303 | — |
| Local Institution - 106 | Denver | Colorado | 80220 | — |
| Colorado Cancer Research Program | Denver | Colorado | 80222 | — |
| Local Institution - 062 | Glenwood Springs | Colorado | 81601 | — |
| Praxair Cancer Center Danbury | Danbury | Connecticut | 06810 | — |
| Medical Oncology and Blood Disorders, LLP | Manchester | Connecticut | 06040 | — |
| Local Institution - 041 | Norwalk | Connecticut | 06851 | — |
| Hematology Oncology Associates, PC | Stamford | Connecticut | 06902 | — |
| Local Institution - 149 | Trumbull | Connecticut | 06611 | — |
| Local Institution - 116 | Waterbury | Connecticut | 067014 | — |
| Local Institution - 068 | Fleming Island | Florida | 32003 | — |
| Mount Sinai Comprehensive Cancer Center | Miami Beach | Florida | 33140 | — |
| Local Institution - 054 | Ocala | Florida | 34474 | — |
| Local Institution - 114 | Pensacola | Florida | 32504 | — |
| Local Institution - 011 | Marietta | Georgia | 30060 | — |
| Local Institution - 083 | Newnan | Georgia | 30265 | — |
| Local Institution - 108 | Elk Grove Village | Illinois | 60007 | — |
| United States Department of Veterans Affairs - VA Great Lakes Health Care System - Edward Hines Jr | Hines | Illinois | 60141 | — |
| Local Institution - 159 | Hinsdale | Illinois | 60521 | — |
| Local Institution - 056 | Niles | Illinois | 60714 | — |
| Local Institution - 028 | Park Ridge | Illinois | 60068 | — |
| Orchard Healthcare Research Inc. | Skokie | Illinois | 60077 | — |
| American Health Network of Indiana, LLC | New Albany | Indiana | 47150 | — |
| McFarland Clinic | Ames | Iowa | 50010 | — |
| Siouxland Hematology-Oncology Associates, LLP | Sioux City | Iowa | 51101-1733 | — |
| Cedar Valley Medical Specialists | Waterloo | Iowa | 50701 | — |
| Local Institution - 019 | Fairway | Kansas | 66205 | — |
| Local Institution - 350 | Great Bend | Kansas | 67530 | — |
| Kentucky Cancer Clinic | Hazard | Kentucky | 41701 | — |
| Local Institution - 138 | Louisville | Kentucky | 40207 | — |
| Local Institution - 143 | Waterville | Maine | 04901 | — |
| Anne Arundel Medical Center | Annapolis | Maryland | 21401 | — |
| Local Institution - 030 | Baltimore | Maryland | 21204 | — |
| Associates Of Oncology/Hematology, P.C. | Rockville | Maryland | 20850 | — |
| Local Institution - 051 | Ann Arbor | Michigan | 48106 | — |
| Local Institution - 033 | Lansing | Michigan | 48912 | — |
| Local Institution - 164 | Rochester | Minnesota | 55905 | — |
| Local Institution - 050 | Bolivar | Missouri | 65613 | — |
| Local Institution - 103 | Columbia | Missouri | 65212 | — |
| Local Institution - 013 | Springfield | Missouri | 65804 | — |
| Local Institution - 042 | St Louis | Missouri | 63110 | — |
| Local Institution - 003 | Lincoln | Nebraska | 68510 | — |
| Local Institution - 098 | Lebanon | New Hampshire | 03756 | — |
| Summit Medical Group Overlook Oncology Center | Berkeley Heights | New Jersey | 07922 | — |
| Veterans Affairs New Jersey Health Care System | East Orange | New Jersey | 07018 | — |
| Local Institution - 080 | Englewood | New Jersey | 07631 | — |
| Local Institution - 025 | Mount Holly | New Jersey | 08060 | — |
| Saint Peter'S University Hospital | New Brunswick | New Jersey | 08901 | — |
| Brookdale University Hospital and Medical Center | Brooklyn | New York | 11212 | — |
| C.R. Wood Cancer Center at Glens Falls Hospital | Glens Falls | New York | 12801 | — |
| Broome Oncology, LLC | Johnson City | New York | 13790 | — |
| Local Institution - 152 | Lake Success | New York | 11042 | — |
| Local Institution - 023 | Kinston | North Carolina | 28501-1584 | — |
| Local Institution - 039 | Raleigh | North Carolina | 27607 | — |
| Summa Health System Akron City Hospital Laboratory | Akron | Ohio | 44202 | — |
| Aultman Hospital | Canton | Ohio | 44710 | — |
| Local Institution - 161 | Cincinnati | Ohio | 45242 | — |
| Local Institution - 047 | Cleveland | Ohio | 44109 | — |
| Local Institution - 045 | Columbus | Ohio | 43219 | — |
| Toledo Clinic Cancer Center | Toledo | Ohio | 43623 | — |
| Local Institution - 037 | Oklahoma City | Oklahoma | 73104 | — |
| Local Institution - 059 | Eugene | Oregon | 97401 | — |
| Hematology Oncology Associates, P.C. | Medford | Oregon | 97504 | — |
| Local Institution - 073 | Greenville | South Carolina | 29615 | — |
| Spartanburg Regional Healthcare System - Gibbs Cancer Center & Research Institute | Spartanburg | South Carolina | 29303 | — |
| Rapid City Regional Hospital | Rapid City | South Dakota | 57701 | — |
| Local Institution - 153 | Sioux Falls | South Dakota | 57105 | — |
| Baptist Cancer Center | Memphis | Tennessee | 38104 | — |
| Local Institution - 076 | Memphis | Tennessee | 38104 | — |
| Local Institution - 166 | Amarillo | Texas | 79106 | — |
| Arlington Cancer Center | Arlington | Texas | 76012 | — |
| Texas Oncology-Arlington South | Arlington | Texas | 76014 | — |
| Local Institution - 105 | Dallas | Texas | 75230 | — |
| Local Institution - 026 | Houston | Texas | 77030 | — |
| Local Institution - 067 | Houston | Texas | 77030 | — |
| Local Institution - 008 | Houston | Texas | 77090 | — |
| Local Institution - 021 | Plano | Texas | 75093 | — |
| Local Institution - 071 | Round Rock | Texas | 78681 | — |
| Local Institution - 070 | San Antonio | Texas | 78217 | — |
| Local Institution - 058 | San Antonio | Texas | 78240 | — |
| Local Institution - 111 | Temple | Texas | 66205 | — |
| Local Institution - 094 | Tyler | Texas | 75701 | — |
| Local Institution - 163 | Tyler | Texas | 75702 | — |
| Local Institution - 057 | Webster | Texas | 77598-4420 | — |
| Local Institution - 090 | Salt Lake City | Utah | 84106 | — |
| Rutland Regional Medical Center | Rutland | Vermont | 05701 | — |
| Local Institution - 053 | Christiansburg | Virginia | 24073 | — |
| Local Institution - 129 | Fort Belvoir | Virginia | 22060 | — |
| Local Institution - 081 | Norfolk | Virginia | 23502 | — |
| Cancer Treatment Center of America | Portsmouth | Virginia | 23704 | — |
| PeaceHealth St. Joseph Medical Center | Bellingham | Washington | 98225 | — |
| Local Institution - 049 | Gig Harbor | Washington | 98332 | — |
| Local Institution - 119 | Olympia | Washington | 98502 | — |
| Seattle Cancer Care Alliance | Seattle | Washington | 98109 | — |
| Local Institution - 104 | Vancouver | Washington | 98684 | — |
| Local Institution - 099 | Walla Walla | Washington | 99362 | — |
| Local Institution - 006 | Wenatchee | Washington | 98801 | — |
| Local Institution - 038 | Morgantown | West Virginia | 26506 | — |
| Aurora Health Care Aurora Research | Milwaukee | Wisconsin | 53233 | — |
| Local Institution - 301 | Mukwonago | Wisconsin | 53145 | — |
| Local Institution - 300 | Oconomowoc | Wisconsin | 53066 | — |
| Local Institution - 101 | Waukesha | Wisconsin | 53188-5099 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01996865, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 10, 2025 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01996865 live on ClinicalTrials.gov.