Safety and Efficacy of Eculizumab in Refractory Generalized Myasthenia Gravis (REGAIN Study)
Public ClinicalTrials.gov record NCT01997229. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Safety and Efficacy of Eculizumab in Subjects With Refractory Generalized Myasthenia Gravis (gMG)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine if eculizumab is safe and effective for the treatment of refractory generalized Myasthenia Gravis.
Study identification
- NCT ID
- NCT01997229
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 125 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2013 (Type not available)
- Primary completion
- Feb 2016 (Actual)
- Completion
- Jun 2016 (Actual)
- Last update posted
- Jul 16, 2019
2013 – 2016
United States locations
- U.S. sites
- 41
- U.S. states
- 23
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama | Birmingham | Alabama | 35233 | — |
| University of California San Francisco-Fresno | Fresno | California | 93720 | — |
| University of Southern California | Los Angeles | California | 90033 | — |
| University of California-Irvine | Orange | California | 92868 | — |
| University of California Davis Health System | Sacramento | California | 95765 | — |
| California Pacific Medical Center | San Francisco | California | 94115 | — |
| Stanford University School of Medicine | Stanford | California | 94305 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 06510 | — |
| University of Florida Health Science Center | Jacksonville | Florida | 32209 | — |
| University of Miami School of Medicine | Miami | Florida | 33136 | — |
| University of South Florida | Tampa | Florida | 33612 | — |
| Georgia Regents University | Augusta | Georgia | 30912 | — |
| Medical Associates of North Georgia | Canton | Georgia | 30114 | — |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| University of Iowa College of Medicine | Iowa City | Iowa | 52242 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Johns Hopkins University School Of Medicine | Baltimore | Maryland | 21287-0876 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Lahey Clinic Inc. | Burlington | Massachusetts | 01805 | — |
| Wayne State University School of Medicine | Detroit | Michigan | 48201 | — |
| Las Vegas Clinic | Las Vegas | Nevada | 89145 | — |
| Buffalo General Hospital | Buffalo | New York | 14203 | — |
| Hospital For Special Surgery/New York Presbyterian Hospital Cornell Campus | New York | New York | 10021 | — |
| Mount Sinai School of Medicine | New York | New York | 10029 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Carolinas Healthcare System | Charlotte | North Carolina | 28207 | — |
| Duke University Health System | Durham | North Carolina | 27705 | — |
| Ohio State University Medical Center | Columbus | Ohio | 43210 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02905 | — |
| Wesley Neurology Clinic | Cordova | Tennessee | 38018 | — |
| Vanderbilt Medical Center | Nashville | Tennessee | 37232 | — |
| UT Southwestern | Dallas | Texas | 75390 | — |
| Methodist Neurological Institute | Houston | Texas | 77030 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| University of Vermont Medical Center | Burlington | Vermont | 05405 | — |
| University of Washington | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 73 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT01997229, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 16, 2019 · Synced Oct 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT01997229 live on ClinicalTrials.gov.