Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss
Public ClinicalTrials.gov record NCT02008357. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4 Study)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to test whether an investigational drug called solanezumab can slow the progression of memory problems associated with brain amyloid (protein that forms plaques in the brains of people with Alzheimer Disease \[AD\]).
Study identification
- NCT ID
- NCT02008357
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,169 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 65 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2014 (Actual)
- Primary completion
- Dec 27, 2022 (Actual)
- Completion
- Jun 8, 2023 (Actual)
- Last update posted
- Aug 21, 2026
2014 – 2023
United States locations
- U.S. sites
- 62
- U.S. states
- 31
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Banner Health Research Institute | Phoenix | Arizona | 85006 | — |
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Banner Sun Health Research Institute | Sun City | Arizona | 85351 | — |
| Institute for Memory Impairment & Neurological Disorders | Irvine | California | 92697 | — |
| University of California - San Diego | La Jolla | California | 92037 | — |
| University of Southern California School of Medicine | Los Angeles | California | 90033 | — |
| University of California - Los Angeles | Los Angeles | California | 90095 | — |
| Univ of California Irvine College of Medicine | Orange | California | 92868 | — |
| Veterans Affairs Medical Center Palo Alto | Palo Alto | California | 94304 | — |
| Sutter Medical Group | Sacramento | California | 95816 | — |
| Univ of California San Francisco | San Francisco | California | 94158 | — |
| Syrentis Clinical Research | Santa Ana | California | 92705 | — |
| University of California, Davis - Health Systems | Walnut Creek | California | 94598 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06510 | — |
| Georgetown University Hospital | Washington D.C. | District of Columbia | 20057 | — |
| Howard University Hospital | Washington D.C. | District of Columbia | 20060 | — |
| Brain Matters Research | Delray Beach | Florida | 33445 | — |
| Mayo Clinic-Jacksonville | Jacksonville | Florida | 32224 | — |
| Wien Center for Clinical Research | Miami Beach | Florida | 33140 | — |
| Compass Research - Orlando | Orlando | Florida | 32806 | — |
| University of South Florida | Tampa | Florida | 33613 | — |
| Compass Research -The Villages | The Villages | Florida | 32162 | — |
| Premiere Research Institute at Palm Beach Neurology | West Palm Beach | Florida | 33407 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Rush Alzheimer's Disease Center | Chicago | Illinois | 60612 | — |
| Great Lakes Clinical Trials | Chicago | Illinois | 60640 | — |
| Indiana University School of Medicine | Indianapolis | Indiana | 46202 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| University of Kansas Hospital | Fairway | Kansas | 66205 | — |
| University of Kentucky | Lexington | Kentucky | 40504 | — |
| Pennington Biomedical Research Center | Baton Rouge | Louisiana | 70808-4124 | — |
| Johns Hopkins University School of Medicine | Baltimore | Maryland | 21093 | — |
| Brigham and Womens Hospital | Boston | Massachusetts | 02115 | — |
| Boston University Medical Center | Boston | Massachusetts | 02118 | — |
| University of Michigan | Ann Arbor | Michigan | 48105 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Univ of Nebraska Med Center | Omaha | Nebraska | 68198 | — |
| Cleveland Clinic of Las Vegas | Las Vegas | Nevada | 89106 | — |
| Dent Neurological Institute | Amherst | New York | 14226 | — |
| New York University Medical Center | New York | New York | 10016 | — |
| Weill Cornell Medical College | New York | New York | 10021 | — |
| Mount Sinai School of Medicine | New York | New York | 10029 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| University of Rochester | Rochester | New York | 14620 | — |
| Wake Forest University School of Medicine | Winston-Salem | North Carolina | 27157 | — |
| Case Western Reserve University | Beachwood | Ohio | 44122 | — |
| Tulsa Clinical Research LLC | Tulsa | Oklahoma | 74104 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Drexel University College of Medicine at EPPI | Philadelphia | Pennsylvania | 19102 | — |
| University of Pennsylvania Hospital | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Butler Hospital | Providence | Rhode Island | 02906 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02906 | — |
| Roper Hospital | Charleston | South Carolina | 29401 | — |
| University of Texas Southwestern Medical Center at Dallas | Dallas | Texas | 75235 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Houston Methodist | Houston | Texas | 77030 | — |
| University of Washington School of Medicine | Seattle | Washington | 98108 | — |
| University of Wisconsin-Madison Hospital and Health Clinic | Madison | Wisconsin | 53705 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02008357, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 21, 2026 · Synced Oct 17, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02008357 live on ClinicalTrials.gov.