A Double-Blind Trial of Adjunctive Valacyclovir to Improve Cognition in Early Phase Schizophrenia
Public ClinicalTrials.gov record NCT02008773. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary aim of the study is to determine the efficacy of adjunctive valacyclovir, in comparison to placebo, to improve visual (Brief Visuospatial Memory Test) and working (composite score of the Spatial Span and Letter Number Span tests) memory in individuals who are HSV-1 positive and early in the course of schizophrenia. We hypothesize that individuals who are HSV-1 positive, but not those who are HSV-1 negative, will demonstrate significant valacyclovir efficacy for visual and working memory.
Study identification
- NCT ID
- NCT02008773
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 170 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 40 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 26, 2014 (Actual)
- Primary completion
- Jun 20, 2017 (Actual)
- Completion
- Jun 20, 2017 (Actual)
- Last update posted
- Jan 30, 2019
2014 – 2017
United States locations
- U.S. sites
- 13
- U.S. states
- 7
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| C.I. Trials, Inc.-Los Angeles County | Bellflower | California | 90706 | — |
| University of California, Los Angeles | Los Angeles | California | 90095 | — |
| University of California, Riverside at C.I. Trials, Inc.-Inland Empire | Riverside | California | 92506 | — |
| C.I. Trials, Inc.-Orange County | Santa Ana | California | 92705 | — |
| Yale University | New Haven | Connecticut | 06519 | — |
| Innovative Clinical Research, Inc. | Lauderhill | Florida | 33319 | — |
| Prevention and Recovery Center for Early Psychosis | Indianapolis | Indiana | 46202 | — |
| Indiana University Psychotic Disorders Clinic | Indianapolis | Indiana | 46222 | — |
| University of Kansas Medical Center-Witchita | Wichita | Kansas | 67214 | — |
| Maryland Psychiatric Research Center | Baltimore | Maryland | 21228 | — |
| Centers for Behavioral Health, LLC | Rockville | Maryland | 20850 | — |
| Sheppard Pratt Health System | Towson | Maryland | 21204 | — |
| Laureate Institute for Brain Research | Tulsa | Oklahoma | 74136 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02008773, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 30, 2019 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02008773 live on ClinicalTrials.gov.