Safety and Efficacy of Oral GKT137831 in Patient With Type 2 Diabetes and Albuminuria
Public ClinicalTrials.gov record NCT02010242. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Double-Blind, Randomized, Placebo-Controlled, Phase 2 Study Evaluating the Safety and Efficacy of Oral GKT137831 in Patients With Type 2 Diabetes and Albuminuria
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
NADPH oxidase enzymes (NOX) have been implicated in the development of several diabetic complications including diabetic nephropathy. GKT137831 is the first in class NOX1/4 inhibitor. The primary objective of this study is to evaluate the efficacy of oral GKT137831 in patients with residual albuminuria despite maximal inhibition of the renin angiotensin aldosterone system.
Study identification
- NCT ID
- NCT02010242
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 136 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2013 (Type not available)
- Primary completion
- Feb 2015 (Actual)
- Completion
- Mar 2015 (Actual)
- Last update posted
- Feb 28, 2025
2013 – 2015
United States locations
- U.S. sites
- 20
- U.S. states
- 12
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Advanced Arizona Clinical Research | Tucson | Arizona | 85712 | — |
| The Endocrine Medical Group, Inc | Orange | California | 92868 | — |
| Clinical Research of South Florida | Coral Gables | Florida | 33134 | — |
| The Center for Diabetes and Endocrine Care | Hollywood | Florida | 33021 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 33216 | — |
| Genoma Research Group, Inc. | Miami | Florida | 33165 | — |
| Coral Research Clinic | Miami | Florida | 33175 | — |
| Pines Clinical Research Inc. | Pembroke Pines | Florida | 33028 | — |
| Volunteer Medical Research | Port Charlotte | Florida | 33952 | — |
| John H. Stroger Jr. Hospital of Cook County | Chicago | Illinois | 60612 | — |
| Community Medical Research Partners | Indianapolis | Indiana | 46234 | — |
| Kansas City VA Medical Center | Kansas City | Missouri | 64128 | — |
| Creighton Diabetes Center | Omaha | Nebraska | 68114 | — |
| LLC DBA AccessMD Clinical Research | Dayton | Ohio | 45424 | — |
| Southeast Renal Research Institute | Chattanooga | Tennessee | 37408 | — |
| The University of Texas Southwestern Medical Center | Dallas | Texas | 75201 | — |
| 17070 Red Oak dr Ste 103 | Houston | Texas | 77090 | — |
| Dialysis West University Health System | San Antonio | Texas | 78229 | — |
| McGuire VA Medical Center | Richmond | Virginia | 23249 | — |
| Zablocki VAMC | Milwaukee | Wisconsin | 53095 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 28 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02010242, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 28, 2025 · Synced Oct 29, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02010242 live on ClinicalTrials.gov.