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Completed Phase 2 Interventional

A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS)

ClinicalTrials.gov ID: NCT02024789

Public ClinicalTrials.gov record NCT02024789. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 10:08 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A MULTI-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE 2 STUDY OF THE EFFICACY, SAFETY AND TOLERABILITY OF RG1662 IN ADULTS AND ADOLESCENTS WITH DOWN SYNDROME (CLEMATIS)

Study identification

NCT ID
NCT02024789
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
173 participants

Conditions and interventions

Conditions

Interventions

  • Placebo Drug
  • RG1662 Drug

Drug

Eligibility (public fields only)

Age range
12 Years to 30 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 4, 2014
Primary completion
May 3, 2016
Completion
May 3, 2016
Last update posted
Oct 24, 2017

2014 – 2016

United States locations

U.S. sites
9
U.S. states
8
U.S. cities
9
Facility City State ZIP Site status
Univ of CA San Diego; Neurosciences Comp.Alzheimer's La Jolla California 92037
University of California DAVIS Medical Center; M.I.N.D. Institute, Section of Developmental Behavior Sacramento California 95817
Emory University School of Medicine; Department of Human Genetics & Pediatrics Decatur Georgia 30033
Rush University Medical Center Chicago Illinois 60612
Johns Hopkins Hospital. Baltimore Maryland 21287
Massachusette General Hospital; Medical Genetics Boston Massachusetts 02114
Duke Clin Rsch Institute Durham North Carolina 27710
University of Utah School of Medicine; Department of Pediatrics Salt Lake City Utah 84112
University of Wisconsin Madison, Waisman Center Madison Wisconsin 53705

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 28 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02024789, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 24, 2017 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02024789 live on ClinicalTrials.gov.

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