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Completed Phase 2 Interventional Results available

A Study of Atezolizumab in Participants With Programmed Death - Ligand 1 (PD-L1) Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer

ClinicalTrials.gov ID: NCT02031458

Public ClinicalTrials.gov record NCT02031458. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 25, 2026, 2:31 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II, Multicenter, Single-Arm Study OF Atezolizumab In Patients With PD-L1-Positive Locally Advanced Or Metastatic Non-Small Cell Lung Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This multicenter, single-arm study will evaluate the efficacy and safety of Atezolizumab in participants with PD-L1-positive locally advanced or metastatic non-small cell lung cancer (NSCLC). Participants will receive Atezolizumab 1200 milligrams (mg) intravenously every 3 weeks as long as participants are experiencing clinical benefit as assessed by the investigator, that is , in the absence of unacceptable toxicity or symptomatic deterioration attributed to disease progression.

Study identification

NCT ID
NCT02031458
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
667 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 21, 2014
Primary completion
May 27, 2015
Completion
Jan 10, 2019
Last update posted
Jan 5, 2020

2014 – 2019

United States locations

U.S. sites
37
U.S. states
22
U.S. cities
34
Facility City State ZIP Site status
Banner MD Anderson Cancer Center Gilbert Arizona 85234 —
HonorHealth Research Institute - Bisgrove Scottsdale Arizona 85258 —
City of Hope Comprehensive Cancer Center Duarte California 91010 —
Angeles Clinic & Rsch Inst Los Angeles California 90025 —
City of Hope National Medical Group South Pasadena California 91030 —
Stanford Cancer Center Stanford California 94305-5820 —
University of Colorado Health Science Center; Biomedical Research Bldg. Room 511 Aurora Colorado 80045 —
Yale Cancer Center; Medical Oncology New Haven Connecticut 06520 —
Georgetown University Medical Center Lombardi Cancer Center Washington D.C. District of Columbia 20007 —
Florida Cancer Specialists; SCRI Fort Myers Florida 33901 —
Florida Hospital Cancer Inst Orlando Florida 32804 —
Hematology Oncology Associates of the Treasure Coast Port Saint Lucie Florida 34952 —
Florida Cancer Specialists. St. Petersburg Florida 33705 —
Emory Uni - Winship Cancer Center; Hematology/Oncology Atlanta Georgia 30322 —
Northwest Georgia Oncology Centers PC - Marietta Marietta Georgia 30060 —
Northwestern University; Robert H. Lurie Comp Can Ctr Chicago Illinois 60611 —
University Of Chicago Medical Center; Section Of Hematology/Oncology Chicago Illinois 60637 —
Uni of Maryland; Greenebaum Cancer Center Baltimore Maryland 21201 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Beth Israel Deaconess Med Ctr; Hem/Onc Boston Massachusetts 02215 —
Dana Farber Cancer Institute Boston Massachusetts 02215 —
Washington University School of Medicine St Louis Missouri 63110 —
Dartmouth Hitchcock Medical Center Lebanon New Hampshire 03756 —
Monter Cancer Center Lake Success New York 11042 —
Memorial Sloan Kettering Cancer Center New York New York 10065 —
Carolina BioOncology Institute, PLCC Huntersville North Carolina 28078 —
Oncology Hematology Care Inc Cincinnati Ohio 45242 —
The Cleveland Clinic Foundation Cleveland Ohio 44195 —
Ohio State University; B406 Starling-Loving Hall Columbus Ohio 43210 —
Penn State Milton S. Hershey Medical Center Hershey Pennsylvania 17033 —
Fox Chase Cancer Center; Hematology/Oncology Philadelphia Pennsylvania 19111 —
Tennessee Oncology PLLC - Nashville (20th Ave) Nashville Tennessee 37203 —
MD Anderson Cancer Center Houston Texas 77030 —
Huntsman Cancer Institute; University of Utah Salt Lake City Utah 84112 —
University of Virginia; Office of Sponsored Programs Charlottesville Virginia 22902 —
University of Washington Seattle Cancer Care Alliance Seattle Washington 98195 —
University of Wisconsin Madison Wisconsin 53792 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 73 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02031458, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 5, 2020 · Synced Sep 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02031458 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →