A Study Evaluating Safety and Efficacy of the Addition of ABT-888 Plus Carboplatin Versus the Addition of Carboplatin to Standard Chemotherapy Versus Standard Chemotherapy in Subjects With Early Stage Triple Negative Breast Cancer
Public ClinicalTrials.gov record NCT02032277. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Placebo-Controlled, Double-Blind, Phase 3 Study Evaluating Safety and Efficacy of the Addition of Veliparib Plus Carboplatin Versus the Addition of Carboplatin to Standard Neoadjuvant Chemotherapy Versus Standard Neoadjuvant Chemotherapy in Subjects With Early Stage Triple Negative Breast Cancer (TNBC)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a 3 arm Phase 3 study to evaluate the safety and efficacy of the addition of veliparib plus carboplatin versus the addition of carboplatin to standard neoadjuvant chemotherapy versus standard neoadjuvant chemotherapy in subjects with early stage TNBC.
Study identification
- NCT ID
- NCT02032277
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 634 participants
Conditions and interventions
Conditions
Interventions
- Cyclophosphamide Drug
- Placebo Drug
- Doxorubicin Drug
- Paclitaxel Drug
- Carboplatin Drug
- Veliparib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 99 Years
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 2, 2014 (Actual)
- Primary completion
- Mar 18, 2016 (Actual)
- Completion
- Nov 12, 2020 (Actual)
- Last update posted
- Jan 20, 2021
2014 – 2020
United States locations
- U.S. sites
- 61
- U.S. states
- 26
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Scottsdale Healthcare /ID# 120473 | Scottsdale | Arizona | 85258-4566 | — |
| Mayo Clinic - Scottsdale /ID# 139932 | Scottsdale | Arizona | 85259 | — |
| Arizona Oncology Associates, PC-HOPE /ID# 126137 | Tucson | Arizona | 85711-2701 | — |
| Usc /Id# 123310 | Los Angeles | California | 90033 | — |
| Pacific Cancer Care /ID# 120476 | Salinas | California | 93901 | — |
| Sharp Memorial Hospital /ID# 119861 | San Diego | California | 92123 | — |
| Stanford University School of Med /ID# 130316 | Stanford | California | 94305-2200 | — |
| Cedars-Sinai Medical Center - West Hollywood /ID# 137275 | West Hollywood | California | 90048 | — |
| Christiana Care Health Service /ID# 137823 | Newark | Delaware | 19713 | — |
| Florida Cancer Specialists - Fort Myers /ID# 121835 | Fort Myers | Florida | 33916 | — |
| Florida Cancer Specialists - Fort Myers /ID# 126379 | Fort Myers | Florida | 33916 | — |
| Mayo Clinic /ID# 132349 | Jacksonville | Florida | 32224 | — |
| Mount Sinai Comp Cancer Ctr /ID# 133008 | Miami | Florida | 33140 | — |
| Miami Cancer Institute - Baptist Health South Florida /ID# 126145 | Miami | Florida | 33176 | — |
| UF Health Cancer Center /ID# 141589 | Orlando | Florida | 32806 | — |
| Moffitt Cancer Center /ID# 124063 | Tampa | Florida | 33612-9416 | — |
| University of Illinois - Chicago /ID# 134329 | Chicago | Illinois | 60607 | — |
| Northwestern University Feinberg School of Medicine /ID# 133848 | Chicago | Illinois | 60611-2927 | — |
| University of Chicago DCAM /ID# 120467 | Chicago | Illinois | 60637-1443 | — |
| Loyola University Medical Ctr /ID# 120455 | Maywood | Illinois | 60153 | — |
| OSF St. Anthony Medical Center /ID# 139424 | Rockford | Illinois | 61108 | — |
| Indiana Univ School Medicine /ID# 118215 | Indianapolis | Indiana | 46202 | — |
| Community Rgnal Cancer Care N /ID# 120456 | Indianapolis | Indiana | 46256 | — |
| Horizon Oncology Research Center /ID# 116815 | Lafayette | Indiana | 47905 | — |
| Cancer Center of Kansas /ID# 134720 | Wichita | Kansas | 67214 | — |
| Univ Maryland School Medicine /ID# 119235 | Baltimore | Maryland | 21201 | — |
| St. Joseph Mercy Hospital /ID# 135875 | Ypsilanti | Michigan | 48106 | — |
| Minnesota Oncology Hematology, PA /ID# 126144 | Minneapolis | Minnesota | 55404 | — |
| St. Lukes Cancer Institute /ID# 118775 | Kansas City | Missouri | 64111-5905 | — |
| Comprehensive Cancer Ctrs Neva /ID# 126136 | Las Vegas | Nevada | 89169 | — |
| Solinksy Center for Cancer Care /ID# 131970 | Manchester | New Hampshire | 03103 | — |
| Rutgers Cancer Institute of NJ /ID# 120477 | New Brunswick | New Jersey | 08903 | — |
| Columbia Univ Medical Center /ID# 141588 | New York | New York | 10032-3725 | — |
| Hope Womens Cancer Centers /ID# 119179 | Asheville | North Carolina | 28816 | — |
| Univ NC Chapel Hill /ID# 132893 | Chapel Hill | North Carolina | 27514-4220 | — |
| Univ NC Chapel Hill /ID# 147695 | Chapel Hill | North Carolina | 27514-4220 | — |
| Novant Health Oncology Special /ID# 139890 | Winston-Salem | North Carolina | 27103 | — |
| Sanford Roger Maris Cancer Cen /ID# 132394 | Fargo | North Dakota | 58102 | — |
| Oncology Hematology Care, Inc - Blue Ash /ID# 120478 | Cincinnati | Ohio | 45252 | — |
| University Hospitals Case Medical Center /ID# 141691 | Cleveland | Ohio | 44106 | — |
| Fairview Hospital /ID# 141626 | Cleveland | Ohio | 44111 | — |
| Cleveland Clinic Main Campus /ID# 126378 | Cleveland | Ohio | 44195 | — |
| The Ohio State University /ID# 141587 | Columbus | Ohio | 43210 | — |
| Lehigh Valley Health Network /ID# 133372 | Allentown | Pennsylvania | 18103 | — |
| Guthrie Medical Group, PC /ID# 124397 | Sayre | Pennsylvania | 18840 | — |
| Women and Infants Hospital /ID# 123476 | Providence | Rhode Island | 02905 | — |
| Avera Cancer Institute /ID# 120466 | Sioux Falls | South Dakota | 57105 | — |
| Tennessee Oncology, PLLC /ID# 124566 | Nashville | Tennessee | 37203 | — |
| Texas Oncology - Bedford /ID# 126135 | Bedford | Texas | 76022 | — |
| Texas Oncology - Medical City Dallas /ID# 126140 | Dallas | Texas | 75230 | — |
| Texas Oncology - Medical City Dallas /ID# 126141 | Dallas | Texas | 75230 | — |
| UT Southwestern Medical Center /ID# 133849 | Dallas | Texas | 75390-7208 | — |
| The Ctr for Cancer and Blood D /ID# 120479 | Fort Worth | Texas | 76104 | — |
| Texas Oncology - Memorial City /ID# 126139 | Houston | Texas | 77024 | — |
| Texas Oncology - Plano East /ID# 126143 | Plano | Texas | 75075 | — |
| Texas Oncology - Tyler /ID# 126142 | Tyler | Texas | 75702 | — |
| University of Utah /ID# 118677 | Salt Lake City | Utah | 84112-5500 | — |
| University of Virginia /ID# 122975 | Charlottesville | Virginia | 22908 | — |
| Virginia Commonwealth Univ /ID# 141586 | Richmond | Virginia | 23219 | — |
| Virginia Oncology Associates /ID# 127260 | Virginia Beach | Virginia | 23456 | — |
| Univ of Wisconsin Hosp/Clinics /ID# 120457 | Madison | Wisconsin | 53792-0001 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 97 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02032277, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 20, 2021 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02032277 live on ClinicalTrials.gov.