Imaging Dopamine Release in Depression

ClinicalTrials.gov ID: NCT02033369

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Official title

Ventrostriatal Dopamine Release and Reward Motivation in MDD

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study aims to determine whether ventral striatal dopamine release is a mechanism of reward motivation in major depression, whether dopamine release is low in depression, and whether DA release and reward motivation predict response to dopamine-targeted treatment with pramipexole.

Study identification

NCT ID: NCT02033369
Recruitment status: Completed
Study type: Interventional
Phase: Phase 4
Lead sponsor: New York State Psychiatric Institute; Other
Enrollment: 52 participants

Conditions and interventions

Conditions

Major Depressive Disorder

Interventions

Pramipexole Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 50 Years
Sex: All
Healthy volunteers: Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Feb 2014 (Actual)
Primary completion: Dec 2016 (Actual)
Completion: Jul 2017 (Actual)
Last update posted: Nov 1, 2019

2014 – 2017

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
New York State Psychiatric Institute	New York	New York	10032	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT02033369, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Nov 1, 2019 · Synced Nov 12, 2026