The TIME-2 Study: A Phase 2 Study of AKB-9778, a Novel Tie-2 Activator, in Patients With Diabetic Macular Edema
Public ClinicalTrials.gov record NCT02050828. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Active-Controlled, Double-Masked, Multi-Center Study to Assess the Safety and Efficacy of Daily Subcutaneous AKB-9778 Administered for 3 Months, as Monotherapy or Adjunctive to Ranibizumab, in Subjects With Diabetic Macular Edema
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the safety and efficacy of AKB-9778 administered as daily subcutaneous injections with and without monthly intravitreal injections of ranibizumab for 3 months in patients with diabetic macular edema.
Study identification
- NCT ID
- NCT02050828
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 144 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 2014 (Type not available)
- Primary completion
- Apr 2015 (Actual)
- Completion
- May 2015 (Actual)
- Last update posted
- Mar 16, 2017
2014 – 2015
United States locations
- U.S. sites
- 39
- U.S. states
- 19
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Pheonix | Arizona | 85014 | — |
| Not listed | Pheonix | Arizona | 85020 | — |
| Not listed | Tucson | Arizona | 85704 | — |
| Not listed | Arcadia | California | 91007 | — |
| Not listed | Bakersfield | California | 93309 | — |
| Not listed | Beverly Hills | California | 90211 | — |
| Not listed | Palm Desert | California | 92260 | — |
| Not listed | Sacramento | California | 95819 | — |
| Not listed | Santa Ana | California | 92705 | — |
| Not listed | Santa Barbara | California | 93103 | — |
| Not listed | Golden | Colorado | 80401 | — |
| Not listed | Boynton Beach | Florida | 33426 | — |
| Not listed | Fort Lauderdale | Florida | 33334 | — |
| Not listed | Fort Myers | Florida | 33912 | — |
| Not listed | Miami | Florida | 33126 | — |
| Not listed | Sarasota | Florida | 34239 | — |
| Not listed | Stuart | Florida | 34994 | — |
| Not listed | Winter Haven | Florida | 33880 | — |
| Not listed | Baltimore | Maryland | 21287 | — |
| Not listed | Jackson | Michigan | 49202 | — |
| Not listed | Omaha | Nebraska | 68198 | — |
| Not listed | Reno | Nevada | 89502 | — |
| Not listed | Rochester | New York | 14620 | — |
| Not listed | Charlotte | North Carolina | 28210 | — |
| Not listed | Cincinnati | Ohio | 45242 | — |
| Not listed | Cleveland | Ohio | 44195 | — |
| Not listed | Portland | Oregon | 97210 | — |
| Not listed | Florence | South Carolina | 29501 | — |
| Not listed | Rapid City | South Dakota | 57701 | — |
| Not listed | Nashville | Tennessee | 37203 | — |
| Not listed | Abilene | Texas | 79606 | — |
| Not listed | Austin | Texas | 78705 | — |
| Not listed | Fort Worth | Texas | 76102 | — |
| Not listed | Houston | Texas | 77030 | — |
| Not listed | McAllen | Texas | 78503 | — |
| Not listed | San Antonio | Texas | 78240 | — |
| Not listed | Salt Lake City | Utah | 84107 | — |
| Not listed | Warrenton | Virginia | 20186 | — |
| Not listed | Bellevue | Washington | 98004 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02050828, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 16, 2017 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02050828 live on ClinicalTrials.gov.