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Completed Phase 2 Interventional Results available

Nitrate's Effect on Activity Tolerance in Heart Failure With Preserved Ejection Fraction

ClinicalTrials.gov ID: NCT02053493

Public ClinicalTrials.gov record NCT02053493. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 4:02 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Study identification

NCT ID
NCT02053493
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Adrian Hernandez
Other
Enrollment
110 participants

Conditions and interventions

Conditions

Interventions

  • Isosorbide Mononitrate Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2014
Primary completion
Jan 31, 2015
Completion
Feb 28, 2015
Last update posted
Nov 27, 2016

2014 – 2015

United States locations

U.S. sites
22
U.S. states
13
U.S. cities
15
Facility City State ZIP Site status
Christiana Care Health Services Newark Delaware 19718
Emory University School of Medicine Atlanta Georgia 30322
Northwestern University Chicago Illinois 60611
Johns Hopkins Hospital Baltimore Maryland 21287
Tufts Medical Center Boston Massachusetts 02111
Massachusetts General Hospital Boston Massachusetts 02114
Brigham and Women's Hospital Boston Massachusetts 02115
Boston V.A. Healthcare System West Roxbury Massachusetts 02132
Mayo Clinic Rochester Minnesota 55905
Washington University School of Medicine St Louis Missouri 63110
Duke University Medical Center Durham North Carolina 27705
University Hospitals Case Medical Center Cleveland Ohio 44106
Metro Health System Cleveland Ohio 44109
Cleveland Clinic Foundation Cleveland Ohio 44195
Lancaster General Hospital Lancaster Pennsylvania 17604
University of Pennsylvania Health System Philadelphia Pennsylvania 19104
Jefferson Medical College Philadelphia Pennsylvania 19107
Temple University Hospital Philadelphia Pennsylvania 19140
Michael E Debakey VA Medical Center Houston Texas 77030
University of Utah Hospitals and Clinics Salt Lake City Utah 84132
V.A. Medical Center Salt Lake City Utah 84148
The University of Vermont - Fletcher Allen Health Care Burlington Vermont 05401

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02053493, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 27, 2016 · Synced Jul 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02053493 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →