Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Completed Phase 2 Interventional Results available

Nitrate's Effect on Activity Tolerance in Heart Failure With Preserved Ejection Fraction

ClinicalTrials.gov ID: NCT02053493

Public ClinicalTrials.gov record NCT02053493. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 26, 2026, 8:51 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

A randomized, double-blinded, placebo-controlled crossover study to assess effect of isosorbide mononitrate with dose up-titration on activity tolerance as assessed by (hip-worn, tri-axial) accelerometry.

Study identification

NCT ID
NCT02053493
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Adrian Hernandez
Other
Enrollment
110 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 2014 (Type not available)
Primary completion
Feb 2015 (Actual)
Completion
Mar 2015 (Actual)
Last update posted
Nov 28, 2016

2014 – 2015

United States locations

U.S. sites
22
U.S. states
13
U.S. cities
15
Facility City State ZIP Site status
Christiana Care Health Services Newark Delaware 19718 —
Emory University School of Medicine Atlanta Georgia 30322 —
Northwestern University Chicago Illinois 60611 —
Johns Hopkins Hospital Baltimore Maryland 21287 —
Tufts Medical Center Boston Massachusetts 02111 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Brigham and Women's Hospital Boston Massachusetts 02115 —
Boston V.A. Healthcare System West Roxbury Massachusetts 02132 —
Mayo Clinic Rochester Minnesota 55905 —
Washington University School of Medicine St Louis Missouri 63110 —
Duke University Medical Center Durham North Carolina 27705 —
University Hospitals Case Medical Center Cleveland Ohio 44106 —
Metro Health System Cleveland Ohio 44109 —
Cleveland Clinic Foundation Cleveland Ohio 44195 —
Lancaster General Hospital Lancaster Pennsylvania 17604 —
University of Pennsylvania Health System Philadelphia Pennsylvania 19104 —
Jefferson Medical College Philadelphia Pennsylvania 19107 —
Temple University Hospital Philadelphia Pennsylvania 19140 —
Michael E Debakey VA Medical Center Houston Texas 77030 —
University of Utah Hospitals and Clinics Salt Lake City Utah 84132 —
V.A. Medical Center Salt Lake City Utah 84148 —
The University of Vermont - Fletcher Allen Health Care Burlington Vermont 05401 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02053493, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 28, 2016 · Synced Oct 26, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02053493 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →