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Completed Phase 2 Interventional Results available

A Study to Evaluate the Efficacy and Safety of X0002 Spray in Subjects With Osteoarthritis

ClinicalTrials.gov ID: NCT02067611

Public ClinicalTrials.gov record NCT02067611. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 6, 2026, 3:29 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Multicenter, Randomized, Double Blind, Placebo Controlled, Parallel Group, Dose Range Finding Study to Evaluate the Efficacy and Safety of X0002 Spray Versus Placebo in Subjects With Osteoarthritis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a phase 2, multicenter, randomized, double blind (with dose), placebo controlled, parallel group, proof of concept, and dose range finding study to evaluate the efficacy, safety, and PK of X0002 spray in adult subjects with clinically symptomatic mild to moderate OA of the knee. Objectives of the study: 1. To evaluate the efficacy of X0002 spray compared to placebo for relief of knee pain in subjects with osteoarthritis (OA) of the knee; 2. To assess the safety and tolerability of multiple doses of X0002 when administered as a topical spray.

Study identification

NCT ID
NCT02067611
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Lina Xu
Industry
Enrollment
216 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
35 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 31, 2014
Primary completion
Jul 31, 2015
Completion
Mar 31, 2016
Last update posted
Feb 6, 2018

2014 – 2016

United States locations

U.S. sites
20
U.S. states
12
U.S. cities
20
Facility City State ZIP Site status
Fiel Family & Sports Medicine/Clinical Research Advantage Inc Tempe Arizona 85283-1528
Med Center Carmichael California 95608
Encompass Clinical Research Spring Valley California 91978
Diablo Clinical Research, Inc. Walnut Creek California 94598
New England Research Assoc. Trumbull Connecticut 06611
Clinical Research of South Florida Coral Gables Florida 32720
Avail Clinical Research, LLC DeLand Florida 32720
Health Awareness Inc. Jupiter Florida 33458
Suncoast Clinical Research, Inc New Port Richey Florida 34652
Columbus Regional Research Institute Columbus Georgia 31904
Clinical Trials Technology(CTT) Consultants, Inc. Prairie Village Kansas 66206-1362
Healthcare Research Network Hazelwood Missouri 63042-1755
Sundance Clinical Research, LLC St Louis Missouri 63141-7068
New Mexico Clinical Research & Osteoporosis Center, Inc. Albuquerque New Mexico 87106
Hightop Medical Research Cincinnati Ohio 45224
Prestige Clinical Research, LLC Franklin Ohio 45005
Heritage Valley Medical Group Beaver Pennsylvania 15009
Altoona Center for Clinical Research Duncansville Pennsylvania 16635
Quality Research Inc San Antonio Texas 78209
Health Research of Hampton Roads, Inc Newport News Virginia 23606

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02067611, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 6, 2018 · Synced Sep 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02067611 live on ClinicalTrials.gov.

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