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Completed Phase 1 Interventional

Study of the Glutaminase Inhibitor CB-839 in Hematological Tumors

ClinicalTrials.gov ID: NCT02071888

Public ClinicalTrials.gov record NCT02071888. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 1:22 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Escalating Oral Doses of the Glutaminase Inhibitor CB-839 in Patients With Advanced and/or Treatment-Refractory Hematological Malignancies

Study identification

NCT ID
NCT02071888
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Calithera Biosciences, Inc
Industry
Enrollment
25 participants

Conditions and interventions

Interventions

  • CB-839 Drug
  • CB-839 and low dose dexamethasone Drug
  • CB-839, pomalidomide, and low dose dexamethasone Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 31, 2014
Primary completion
Mar 31, 2016
Completion
Mar 31, 2016
Last update posted
Jul 17, 2018

2014 – 2016

United States locations

U.S. sites
7
U.S. states
7
U.S. cities
7
Facility City State ZIP Site status
Mayo Clinic Scottsdale Arizona 85259-5499
Colorado Blood Cancer Institute Denver Colorado 80218
Winship Cancer Institute of Emory School of Medicine Atlanta Georgia 30322
John Theruer Cancer Center at Hackensack University Medical Center Hackensack New Jersey 07601
Weill Cornell Medical College New York New York 10065
University of Pennsylvania, Abramson Cancer Center Philadelphia Pennsylvania 19104
Tennessee Oncology, PLLC Nashville Tennessee 37203

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02071888, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 17, 2018 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02071888 live on ClinicalTrials.gov.

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