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Terminated Phase 3 Interventional Results available

Evaluation of the Efficacy and Safety of Azeliragon (TTP488) in Patients With Mild Alzheimer's Disease

ClinicalTrials.gov ID: NCT02080364

Public ClinicalTrials.gov record NCT02080364. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 2:38 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Randomized, Double-blind, Placebo Controlled, Multi-center Registration Trial to Evaluate the Efficacy and Safety of Azeliragon (TTP488) in Patients With Mild Alzheimer's Disease Receiving Acetylcholinesterase Inhibitors and/or Memantine

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a study to evaluate the efficacy and safety of azeliragon in patients with mild Alzheimer's disease. Patients will receive either azeliragon or placebo with a patient's participation lasting approximately 18 months.

Study identification

NCT ID
NCT02080364
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
vTv Therapeutics
Industry
Enrollment
880 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 2015 (Actual)
Primary completion
Jun 1, 2018 (Actual)
Completion
Jun 1, 2018 (Actual)
Last update posted
May 7, 2021

2015 – 2018

United States locations

U.S. sites
80
U.S. states
25
U.S. cities
70
Facility City State ZIP Site status
Not listed Phoenix Arizona 85004 —
Not listed Phoenix Arizona 85013 —
Not listed Phoenix Arizona 85018 —
Not listed Tucson Arizona 85724 —
Not listed Tucson Arizona 85741 —
Not listed Bellflower California 90706 —
Not listed Costa Mesa California 92626 —
Not listed Fullerton California 92835 —
Not listed Glendale California 91206 —
Not listed Imperial California 92251 —
Not listed Irvine California 92614 —
Not listed Laguna Hills California 92653 —
Not listed Long Beach California 90806 —
Not listed Long Beach California 90807 —
Not listed Orange California 92868 —
Not listed Riverside California 92506 —
Not listed San Bernardino California 92408 —
Not listed San Francisco California 94114 —
Not listed Santa Ana California 92705 —
Not listed Atlantis Florida 33462 —
Not listed Brooksville Florida 34601 —
Not listed Delray Beach Florida 33445 —
Not listed Hallandale Florida 33009 —
Not listed Hialeah Florida 33016 —
Not listed Jacksonville Florida 32216 —
Not listed Lake Worth Florida 33449 —
Not listed Leesburg Florida 34748 —
Not listed Miami Florida 33122 —
Not listed Miami Florida 33137 —
Not listed Miami Beach Florida 33140 —
Not listed Miami Lakes Florida 33014 —
Not listed Miami Lakes Florida 33016 —
Not listed Orlando Florida 32806 —
Not listed Pensacola Florida 32503 —
Not listed Sarasota Florida 34243 —
Not listed Sunrise Florida 33351 —
Not listed Atlanta Georgia 30331 —
Not listed Columbus Georgia 31909 —
Not listed Chicago Illinois 60640 —
Not listed Fairway Kansas 66205 —
Not listed Prairie Village Kansas 66201 —
Not listed Lexington Kentucky 40504 —
Not listed Baltimore Maryland 21208 —
Not listed Newton Massachusetts 02459 —
Not listed Plymouth Massachusetts 02360 —
Not listed Quincy Massachusetts 01269 —
Not listed Hattiesburg Mississippi 39401 —
Not listed Creve Coeur Missouri 63141 —
Not listed Princeton New Jersey 08540 —
Not listed Albuquerque New Mexico 87109 —
Not listed Albany New York 12208 —
Not listed Lake Success New York 11042 —
Not listed New York New York 10032 —
Not listed Staten Island New York 10312 —
Not listed Charlotte North Carolina 28270 —
Not listed Raleigh North Carolina 27607 —
Not listed Wilmington North Carolina 28401 —
Not listed Winston-Salem North Carolina 27157 —
Not listed Canton Ohio 44718 —
Not listed Shaker Heights Ohio 44122 —
Not listed Oklahoma City Oklahoma 73103 —
Not listed Oklahoma City Oklahoma 73118 —
Not listed Portland Oregon 97210 —
Not listed Portland Oregon 97225 —
Not listed Media Pennsylvania 19063 —
Not listed Norristown Pennsylvania 19403 —
Not listed Plains Pennsylvania 18705 —
Not listed East Providence Rhode Island 02914 —
Not listed East Providence Rhode Island 02916 —
Not listed Charleston South Carolina 24901 —
Not listed Mt. Pleasant South Carolina 29464 —
Not listed Cordova Tennessee 38018 —
Not listed Nashville Tennessee 37203 —
Not listed Dallas Texas 75231 —
Not listed San Antonio Texas 78229 —
Not listed San Antonio Texas 78232 —
Not listed Wichita Falls Texas 76309 —
Not listed Murray Utah 84123 —
Not listed Kirkland Washington 98201 —
Not listed Richland Washington 99352 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 35 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02080364, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 7, 2021 · Synced Oct 17, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT02080364 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →