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Terminated Phase 3 Interventional Results available

Evaluation of the Efficacy and Safety of Azeliragon (TTP488) in Patients With Mild Alzheimer's Disease

ClinicalTrials.gov ID: NCT02080364

Public ClinicalTrials.gov record NCT02080364. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 10:42 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Randomized, Double-blind, Placebo Controlled, Multi-center Registration Trial to Evaluate the Efficacy and Safety of Azeliragon (TTP488) in Patients With Mild Alzheimer's Disease Receiving Acetylcholinesterase Inhibitors and/or Memantine

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a study to evaluate the efficacy and safety of azeliragon in patients with mild Alzheimer's disease. Patients will receive either azeliragon or placebo with a patient's participation lasting approximately 18 months.

Study identification

NCT ID
NCT02080364
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
vTv Therapeutics
Industry
Enrollment
880 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2015
Primary completion
May 31, 2018
Completion
May 31, 2018
Last update posted
May 6, 2021

2015 – 2018

United States locations

U.S. sites
80
U.S. states
25
U.S. cities
70
Facility City State ZIP Site status
Not listed Phoenix Arizona 85004
Not listed Phoenix Arizona 85013
Not listed Phoenix Arizona 85018
Not listed Tucson Arizona 85724
Not listed Tucson Arizona 85741
Not listed Bellflower California 90706
Not listed Costa Mesa California 92626
Not listed Fullerton California 92835
Not listed Glendale California 91206
Not listed Imperial California 92251
Not listed Irvine California 92614
Not listed Laguna Hills California 92653
Not listed Long Beach California 90806
Not listed Long Beach California 90807
Not listed Orange California 92868
Not listed Riverside California 92506
Not listed San Bernardino California 92408
Not listed San Francisco California 94114
Not listed Santa Ana California 92705
Not listed Atlantis Florida 33462
Not listed Brooksville Florida 34601
Not listed Delray Beach Florida 33445
Not listed Hallandale Florida 33009
Not listed Hialeah Florida 33016
Not listed Jacksonville Florida 32216
Not listed Lake Worth Florida 33449
Not listed Leesburg Florida 34748
Not listed Miami Florida 33122
Not listed Miami Florida 33137
Not listed Miami Beach Florida 33140
Not listed Miami Lakes Florida 33014
Not listed Miami Lakes Florida 33016
Not listed Orlando Florida 32806
Not listed Pensacola Florida 32503
Not listed Sarasota Florida 34243
Not listed Sunrise Florida 33351
Not listed Atlanta Georgia 30331
Not listed Columbus Georgia 31909
Not listed Chicago Illinois 60640
Not listed Fairway Kansas 66205
Not listed Prairie Village Kansas 66201
Not listed Lexington Kentucky 40504
Not listed Baltimore Maryland 21208
Not listed Newton Massachusetts 02459
Not listed Plymouth Massachusetts 02360
Not listed Quincy Massachusetts 01269
Not listed Hattiesburg Mississippi 39401
Not listed Creve Coeur Missouri 63141
Not listed Princeton New Jersey 08540
Not listed Albuquerque New Mexico 87109
Not listed Albany New York 12208
Not listed Lake Success New York 11042
Not listed New York New York 10032
Not listed Staten Island New York 10312
Not listed Charlotte North Carolina 28270
Not listed Raleigh North Carolina 27607
Not listed Wilmington North Carolina 28401
Not listed Winston-Salem North Carolina 27157
Not listed Canton Ohio 44718
Not listed Shaker Heights Ohio 44122
Not listed Oklahoma City Oklahoma 73103
Not listed Oklahoma City Oklahoma 73118
Not listed Portland Oregon 97210
Not listed Portland Oregon 97225
Not listed Media Pennsylvania 19063
Not listed Norristown Pennsylvania 19403
Not listed Plains Pennsylvania 18705
Not listed East Providence Rhode Island 02914
Not listed East Providence Rhode Island 02916
Not listed Charleston South Carolina 24901
Not listed Mt. Pleasant South Carolina 29464
Not listed Cordova Tennessee 38018
Not listed Nashville Tennessee 37203
Not listed Dallas Texas 75231
Not listed San Antonio Texas 78229
Not listed San Antonio Texas 78232
Not listed Wichita Falls Texas 76309
Not listed Murray Utah 84123
Not listed Kirkland Washington 98201
Not listed Richland Washington 99352

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 35 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT02080364, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 6, 2021 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT02080364 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →