Safety & Efficacy of Zirconium Silicate Dosed for 28 Days in Hyperkalemia.
Public ClinicalTrials.gov record NCT02088073. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Multicenter, Multi-phase, Multi-dose, Prospective, Double-blind, Placebo-controlled, Maintenance Study of Safety and Efficacy of ZS (Microporous, Fractionated, Protonated Zirconium Silicate) in Hyperkalemia.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
It is hypothesized that ZS is more effective than placebo control (alternative hypothesis) in maintaining mean double-blind randomized maintenance phase (DBRMP) Day 8-29 serum potassium levels (3.5 - 5.0 mmol/l, inclusive) among hyperkalemic subjects in whom normokalemia was established during the open-label acute phase versus no difference between each ZS dose (highest to lowest) versus placebo control (null hypothesis).
Study identification
- NCT ID
- NCT02088073
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 258 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 31, 2014 (Actual)
- Primary completion
- Aug 31, 2014 (Actual)
- Completion
- Jan 31, 2015 (Actual)
- Last update posted
- Dec 7, 2018
2014 – 2015
United States locations
- U.S. sites
- 38
- U.S. states
- 17
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Not listed | Anniston | Alabama | — | — |
| Not listed | Huntsville | Alabama | — | — |
| Not listed | Scottsboro | Alabama | — | — |
| Not listed | Phoenix | Arizona | — | — |
| Not listed | Tempe | Arizona | — | — |
| Not listed | Hawaiian Gardens | California | — | — |
| Not listed | Los Angeles | California | — | — |
| Not listed | Paramount | California | — | — |
| Not listed | Riverside | California | — | — |
| Not listed | Atlantis | Florida | — | — |
| Not listed | Bradenton | Florida | — | — |
| Not listed | Brandon | Florida | — | — |
| Not listed | Brooksville | Florida | — | — |
| Not listed | DeLand | Florida | — | — |
| Not listed | Edgewater | Florida | — | — |
| Not listed | Miami | Florida | — | — |
| Not listed | Miami Lakes | Florida | — | — |
| Not listed | New Smyrna Beach | Florida | — | — |
| Not listed | Ocala | Florida | — | — |
| Not listed | Summerfield | Florida | — | — |
| Not listed | Tampa | Florida | — | — |
| Not listed | Winter Park | Florida | — | — |
| Not listed | Columbus | Georgia | — | — |
| Not listed | Decatur | Georgia | — | — |
| Not listed | Evergreen Park | Illinois | — | — |
| Not listed | Joliet | Illinois | — | — |
| Not listed | Shreveport | Louisiana | — | — |
| Not listed | Auburn | Maine | — | — |
| Not listed | Chesterfield | Michigan | — | — |
| Not listed | Kansas City | Missouri | — | — |
| Not listed | Las Vegas | Nevada | — | — |
| Not listed | Flushing | New York | — | — |
| Not listed | Altoona | Pennsylvania | — | — |
| Not listed | Providence | Rhode Island | — | — |
| Not listed | Orangeburg | South Carolina | — | — |
| Not listed | Sumter | South Carolina | — | — |
| Not listed | Chattanooga | Tennessee | — | — |
| Not listed | San Antonio | Texas | — | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT02088073, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 7, 2018 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT02088073 live on ClinicalTrials.gov.